Heterocyclic Chemistry / Edition 5

Heterocyclic Chemistry / Edition 5

by John A. Joule, Keith Mills
     
 

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ISBN-10: 1405193654

ISBN-13: 9781405193658

Pub. Date: 06/08/2010

Publisher: Wiley

This book has so closely matched the requirements of its readership over the years that it has become the first choice for chemists worldwide.

Heterocyclic chemistry comprises at least half of all organic chemistry research worldwide. In particular, the vast majority of organic work done in the pharmaceutical and agrochemical industries is heterocyclic

Overview

This book has so closely matched the requirements of its readership over the years that it has become the first choice for chemists worldwide.

Heterocyclic chemistry comprises at least half of all organic chemistry research worldwide. In particular, the vast majority of organic work done in the pharmaceutical and agrochemical industries is heterocyclic chemistry.

The fifth edition of Heterocyclic Chemistry maintains the principal objective of earlier editions – to teach the fundamentals of heterocyclic reactivity and synthesis in a way that is understandable to second- and third-year undergraduate chemistry students. The inclusion of more advanced and current material also makes the book a valuable reference text for postgraduate taught courses, postgraduate researchers, and chemists at all levels working with heterocyclic compounds in industry.

Fully updated and expanded to reflect important 21st century advances, the fifth edition of this classic text includes the following innovations:

  • Extensive use of colour to highlight changes in structure and bonding during reactions
  • Entirely new chapters on organometallic heterocyclic chemistry, heterocyclic natural products, especially in biochemical processes, and heterocycles in medicine
  • New sections focusing on heterocyclic fluorine compounds, isotopically labeled heterocycles, and solid-phase chemistry, microwave heating and flow reactors in the heterocyclic context

Essential teaching material in the early chapters is followed by short chapters throughout the text which capture the essence of heterocyclic reactivity in concise resumés suitable as introductions or summaries, for example for examination preparation. Detailed, systematic discussions cover the reactivity and synthesis of all the important heterocyclic systems. Original references and references to reviews are given throughout the text, vital for postgraduate teaching and for research scientists. Problems, divided into straightforward revision exercises, and more challenging questions (with solutions available online), help the reader to understand and apply the principles of heterocyclic reactivity and synthesis.

Product Details

ISBN-13:
9781405193658
Publisher:
Wiley
Publication date:
06/08/2010
Pages:
718
Sales rank:
1,027,587
Product dimensions:
7.60(w) x 9.90(h) x 1.60(d)

Table of Contents

Preface.

Introduction to the fourth edition.

Definitions and abbreviations.

1. Structures and spectroscopic properties of aromatic heterocycles,.

2. Reactivity of aromatic heterocycles.

3. Synthesis of aromatic heterocycles.

4. Typical reactivity of pyridines, quinolines and isoquinolines.

5. Pyridines: reactions and synthesis.

6. Quinolines and isoquinolines: reactions and synthesis.

7. Typical reactivity of pyrylium and benzopyrylium ions, pyrones and.

benzopyrones.

8. Pyryliums, 2- and 4-pyrones: reactions and synthesis.

9. Benzopyryliums, benzopyrones: reactions and synthesis.

10. Typical reactivity of the diazines: pyridazine, pyrimidine and pyrazine.

11. The diazines: pyridazine, pyrimidine, and pyrazine: reactions and synthesis.

12. Typical reactivity of pyrroles, thiophenes, and furans.

13. Pyrroles: reactions and synthesis.

14. Thiophenes: reactions and synthesis.

15. Furans: reactions and synthesis.

16. Typical reactivity of indoles, benzo[b]thiophenes, benzo[b]furans,.

isoindoles, benzo[c]thiophenes and isobenzofurans.

17. Indoles: reactionsand synthesis.

18. Benzo[b]thiophenes and benzo[b]furans: reactions and synthesis.

19. Isoindoles, benzo[c]thiophenes and isobenzofurans: reactions and synthesis.

21. 1,3-Azoles:imidazoles, thiazoles, and oxazoles: reactions and synthesis.

22. 1,2Azoles: pyrazoles, isothiazoles, isoxazoles: reactions and synthesis.

23. Benzanellated azoles: reactions and synthesis.

24. Purines: reactions and synthesis.

25. Heterocycles containing a ring-junction nitrogen.

26. Heterocycles containing more than two hetero atoms.

27. Saturated and partially unsaturated heterocyclic compounds:.

28. Heterocycles at work.

Appendix: answers to exercises.

Index.

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