High Dose Cancer Therapy: Pharmacology, Hematopoietins, Stem Cells / Edition 3

High Dose Cancer Therapy: Pharmacology, Hematopoietins, Stem Cells / Edition 3

by James O. Armitage

ISBN-10: 0683306545

ISBN-13: 9780683306545

Pub. Date: 01/28/2000

Publisher: Lippincott Williams & Wilkins

Product Details

Lippincott Williams & Wilkins
Publication date:
Edition description:
Product dimensions:
7.09(w) x 9.84(h) x (d)

Table of Contents

Sect. IStrategies for the Use of Agents at High Dose
1Pharmacologic Strategies for High-Dose Chemotherapy3
2Preclinical Models for High-Dose Therapy14
4Strategies for the Use of Total Body Irradiation as Systemic Therapy in Leukemia and Lymphoma61
5Radioimmunoglobulin Therapy84
6What Is the Best Strategy for Bone Marrow Transplantation Cancer?124
7Analysis of Economic Issues127
Sect. IIReestablishing Hematopoiesis after Dose-Intensive Therapy
8The Hematopoietic Microenvironment143
9Reconstitution of Hematopoiesis Following Allogeneic Bone Marrow Transplantation151
10Autologous Bone Marrow Transplantation162
11Reestablishing Hematopoiesis After Dose-Intensive Therapy with Peripheral Stem Cells182
12High-Dose Cancer Therapy Without Stem Cell Support - Human Solid Tumors195
13Immunologic Reconstitution After High-Dose Chemoradiotherapy and Allogeneic or Autologous Bone Marrow or Peripheral Blood Hematopoietic Stem Cell Transplantation211
Marrow Contamination
14Marrow Contamination: Detection and Significance226
15Bone Marrow Purging249
16Marrow Contamination: Positive Selection276
Growth Factors
17Hematopoietic Growth Factors289
18Granulocyte-Monocyte Colony-Stimulating Factor314
19Delivery of High-Dose Chemotherapy with Recombinant Human Granulocyte Colony-Stimulating Factor Support333
20Macrophage Colony-Stimulating Factor: Biology and Clinical Applications344
21Interleukin 3: General Biology, Preclinical and Clinical Studies362
22Erythropoietin in High-Dose Chemotherapy385
Sect. IIILaboratory and Clinical Support for Dose-Intensive Therapy
23Nursing for Patients Receiving High-Dose Chemotherapy with Hematopoietic Rescue405
24Hickman Line Management419
25Blood Bank Support in Patients Undergoing High-Dose Cancer Therapy437
26Infectious Diseases456
27Pulmonary Complications of Bone Marrow Transplantation473
28Hepatic Complications of Bone Marrow Transplantation487
29The Cardiovascular System and Anticancer Therapy505
31Genitourinary, Gastrointestinal, and Other Complications547
32Gonadal Complications555
Sect. IVClinical Applications of High-Dose Therapy
33High-Dose Therapy for Acute Myelocytic Leukemia569
34High-Dose Therapy in Acute Lymphoblastic Leukemia607
35Intensive Therapy of Chronic Myelogenous Leukemia619
36High-Dose Therapy and Allogeneic Bone Marrow Transplantation in Chronic Lymphocytic Leukemia626
37High-Dose Therapy, Autologous Stem Cells, and Hematopoietic Growth Factors for the Management of Multiple Myeloma638
38Autologous Bone Marrow Transplantation for Hodgkin's Disease651
39High-Dose Therapy for the Treatment of Non-Hodgkin's Lymphoma662
40High-Dose Therapy in Burkitt's Lymphoma677
41High-Dose Chemotherapy in the Management of Malignant Germ Cell Tumors690
42Dose-Intensive Therapy in Breast Cancer701
43High-Dose Chemotherapy with Autologous Bone Marrow Support for Lung Cancer719
44High-Dose Chemotherapy and Autologous Marrow Transplantation for Common Epithelial Ovarian Cancer729
45Myeloablative Treatment Supported by Marrow Infusions for Children with Neuroblastoma735
46Dose-Intensive Therapy for Advanced Melanoma750
47High-Dose Therapy for Brain Tumors: Rationale, Results, and Revelations755
48Autologous Bone Marrow Transplantation for Miscellaneous Tumors763

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