High-Resolution Electrophoresis and Immunofixation: Techniques and Interpretation

Overview


The second edition of this well-known explication of the techniques and interpretations of electrophoresis and immunofixation has been thoroughly updated. Incorporating the changes in technology since the first edition was published, the author has made extensive revisions, entirely replacing the section on immunoelectrophoresis with a discussion of the current technique of immunofixation. The majority of the original illustrations have been revised, and a new section on the interpretation of oligoclonal bans in...
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Stoneham, MA 1987 Hard Cover Good, Not Marked 8veo-over 7?"-9?" Tall.

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Overview


The second edition of this well-known explication of the techniques and interpretations of electrophoresis and immunofixation has been thoroughly updated. Incorporating the changes in technology since the first edition was published, the author has made extensive revisions, entirely replacing the section on immunoelectrophoresis with a discussion of the current technique of immunofixation. The majority of the original illustrations have been revised, and a new section on the interpretation of oligoclonal bans in cerebrospinal fluid has been included.

The book contains black-and-white illustrations.

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Editorial Reviews

Earle W. Holmes
This practically oriented text covers the theory, technique, and interpretation of electrophoresis, immunofixation, and immunoelectrophoresis. The book is devoted to the application of these techniques to the clinical laboratory analysis of serum protein abnormalities. The book is designed to acquaint the reader with the latest methodologies and instrumentation available and to facilitate the use of electrophoretic techniques in clinical diagnosis and management. This book is aimed at clinical laboratory personnel, including clinical chemists, pathologists, medical technologists as well as pathology residents and other trainees in laboratory medicine. The text contains more than 170 photographs of electrophoresis, immunofixation, and immunoelectrophoresis gels that represent the whole spectrum of abnormalities that would be encountered clinically. The last chapter comprises illustrated examples presented in a case study format. This is an essential resource for anyone responsible for signing out cases involving electrophoresis studies. In addition to his own substantial experience in this area, the author has incorporated case material contributed by other authorities in the field. The book presents a wealth of practical knowledge that could otherwise be obtained only through years of experience. The book is a valuable teaching tool that should be in the personal libraries of instructors in clinical pathology and in the libraries of institutions with programs in medical technology, medicine, or pathology.
Booknews
A text that acquaints readers with the available methodologies and instrumentation for performing high-resolution electrophoresis and immunofixation; presents a strategy for using these procedures to facilitate the diagnosis of a variety of serum protein abnormalities; and presents a large number of cases to illustrate the uses of these new procedures. This edition (1st ed., 1987) has been largely rewritten to reflect the significant advances that have been made both in the technology of serum protein electrophoresis and in the knowledge about the electrophoretic patterns encountered when using high-resolution electrophoresis and immunofixation. Annotation c. Book News, Inc., Portland, OR (booknews.com)
From The Critics
Reviewer: Earle W. Holmes, PhD(Loyola University Medical Center)
Description: This practically oriented text covers the theory, technique, and interpretation of electrophoresis, immunofixation, and immunoelectrophoresis. The book is devoted to the application of these techniques to the clinical laboratory analysis of serum protein abnormalities.
Purpose: The book is designed to acquaint the reader with the latest methodologies and instrumentation available and to facilitate the use of electrophoretic techniques in clinical diagnosis and management.
Audience: This book is aimed at clinical laboratory personnel, including clinical chemists, pathologists, medical technologists as well as pathology residents and other trainees in laboratory medicine.
Features: The text contains more than 170 photographs of electrophoresis, immunofixation, and immunoelectrophoresis gels that represent the whole spectrum of abnormalities that would be encountered clinically. The last chapter comprises illustrated examples presented in a case study format.
Assessment: This is an essential resource for anyone responsible for signing out cases involving electrophoresis studies. In addition to his own substantial experience in this area, the author has incorporated case material contributed by other authorities in the field. The book presents a wealth of practical knowledge that could otherwise be obtained only through years of experience. The book is a valuable teaching tool that should be in the personal libraries of instructors in clinical pathology and in the libraries of institutions with programs in medical technology, medicine, or pathology.

4 Stars! from Doody
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Product Details

  • ISBN-13: 9780409900217
  • Publisher: Elsevier Science & Technology Books
  • Publication date: 1/1/1987
  • Pages: 248

Meet the Author

Keren, David MD, Warde Medical Laboratory, Ann Arbor, Michigan, USA

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Table of Contents

Preface to the First Edition
Preface to the Second Edition
1 Methods and Rationale for High-Resolution Electrophoresis 1
2 Techniques for High-Resolution Electrophoresis 17
3 Proteins in Serum Identified by High-Resolution Electrophoresis 41
4 Approaches to Pattern Interpretation in Serum 97
5 Approaches to Pattern Interpretation in Cerebrospinal Fluid and Urine 131
6 Immunofixation Technique 171
7 Conditions Associated With Monoclonal Gammopathies 211
8 Laboratory Diagnosis of Monoclonal Gammopathies 283
9 Case Studies for Interpretation 313
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