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Doody's Review ServiceReviewer: Bruce A. Fenderson, PhD (Thomas Jefferson University)
Description: Basic knowledge of cell and molecular biology is of increasing importance for sound medical practice. Future physicians need to understand the molecular language of life in order to interpret laboratory data and provide effective personalized medicine. This concise paperback reviews key concepts in this area and identifies high-yield facts that are useful for board review. Its 16 chapters cover traditional topics from the nuclear genome to the immune system and principles of gene therapy. The focus is on cellular and molecular biology.
Purpose: According to the author, the aim is to help readers understand molecular biology from a clinical perspective. With this purpose in mind, the author has consolidated high-yield information from various preclinical courses for the benefit of students preparing for national licensing examinations.
Audience: The book is intended primarily for students of medicine, dentistry, cytotechnology, nursing, and laboratory medicine. It is written by an expert scientist and medical educator, who assumes that readers will have taken, or are taking, advanced courses in biochemistry as well as cell and molecular biology.
Features: This compact, user-friendly review is filled with innumerable details on genes, mutations, and regulatory pathways. The illustrations and line drawings are informative and well done. Each chapter includes a clinical consideration section that provides medically-relevant examples. Photomicrographs illustrating pathologic findings help communicate clinical relevance. Chromosomal locations for known human genetic diseases are included in an appendix.
Assessment: This revised third edition provides a wonderful compendium of need-to-know facts for students of medicine. It is well organized, informative, and well written. My only concern is that the book contains too much information (technical jargon). Students will want to read critically — absorbing content that is appropriate for their medical education. This book succeeds in pulling together recent findings in cell and molecular biology to help students learn the foundations of clinical medicine and succeed on licensing examinations.