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Doody's Review ServiceReviewer: Hector Lopez, MD (Thomas Jefferson University)
Description: Histology as a field is currently integrating discoveries in cellular and developmental biology with human form and function. It provides an essential foundation for clinical medicine. Students learn how tissues and organs are constructed at cellular and subcellular levels of organization. This body of knowledge enables students to evaluate normal tissue differentiation and begin to interpret pathologic aspects of disease. This beautiful softcover textbook provides a complete overview of human microscopic anatomy. It includes illuminating text, outstanding color plates, and a wonderful correlation of traditional topics with modern research findings in cellular and molecular biology. This updated fifth edition includes 25 chapters that cover basic concepts in cell biology, core principles of tissue structure and function, and concise overviews of microanatomy using an organ-system approach. The photomicrographs clearly identify structures viewed under the microscope.
Purpose: According to the authors, the aim of this book is to lead the student to "understand the microanatomy of cells, tissues, and organs and to correlate structure with function."
Audience: The book is written for students of medicine, dentistry, and the allied health professions (e.g., cytotechnology and physical therapy).
Features: This full-color book is student friendly and easy to read. It is color coded throughout to help students with navigation. The chapters contain color boxes that highlight "clinical correlations" and "functional considerations." The full-color illustrations and photomicrographs are outstanding and educational. Most chapters contain large-format labeled atlas plates with detailed legends. You only need one book to really get to the point. The authors provide details regarding common laboratory methods used to obtain histopathologic information (e.g., immunolabeling and autoradiography). The clinical correlations and functional considerations are incredibly useful for both teaching faculty and students. I was impressed with the seamless way in which the authors address functions of tissues (e.g., epithelial tissues) by considering their unique cellular and subcellular biology. Examples of new topics in cell biology include lipid rafts and docking of intracellular transport vesicles. The care taken by the authors to teach students is clearly illustrated in a side-by-side comparison of sections through a renal corpuscle and a common orange. The book is packed with details. For example, one table provides a complete list of proteins that partner with specific adhesion molecules.
Assessment: This is a wonderful microscopic anatomy book. The authors combine traditional topics in histology with modern research findings in cellular and molecular biology. It is written by leading experts for a wide audience of students in the biomedical and life sciences. It is comprehensive, visually attractive, and well written. This is the body of information that students of microanatomy need to know to understand pathology and succeed on licensing examinations (USMLE). It will provide an excellent educational resource for years to come. In addition to core concepts, students are presented with a vision of biological design that underlies the beauty of human morphology at the microscopic level.