A History of Molecular Biology / Edition 1

A History of Molecular Biology / Edition 1

by Michel Morange
     
 

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ISBN-10: 0674398556

ISBN-13: 9780674398559

Pub. Date: 07/15/1998

Publisher: Harvard University Press

Every day it seems the media focus on yet another new development in biology—gene therapy, the human genome project, the creation of new varieties of animals and plants through genetic engineering. These possibilities have all emanated from molecular biology.

A History of Molecular Biology is a complete but compact account for a general readership of

Overview

Every day it seems the media focus on yet another new development in biology—gene therapy, the human genome project, the creation of new varieties of animals and plants through genetic engineering. These possibilities have all emanated from molecular biology.

A History of Molecular Biology is a complete but compact account for a general readership of the history of this revolution. Michel Morange, himself a molecular biologist, takes us from the turn-of-the-century convergence of molecular biology's two progenitors, genetics and biochemistry, to the perfection of gene splicing and cloning techniques in the 1980s. Drawing on the important work of American, English, and French historians of science, Morange describes the major discoveries—the double helix, messenger RNA, oncogenes, DNA polymerase—but also explains how and why these breakthroughs took place. The book is enlivened by mini-biographies of the founders of molecular biology: Delbrück, Watson and Crick, Monod and Jacob, Nirenberg.

This ambitious history covers the story of the transformation of biology over the last one hundred years; the transformation of disciplines: biochemistry, genetics, embryology, and evolutionary biology; and, finally, the emergence of the biotechnology industry.

An important contribution to the history of science, A History of Molecular Biology will also be valued by general readers for its clear explanations of the theory and practice of molecular biology today. Molecular biologists themselves will find Morange's historical perspective critical to an understanding of what is at stake in current biological research.

Product Details

ISBN-13:
9780674398559
Publisher:
Harvard University Press
Publication date:
07/15/1998
Pages:
336
Product dimensions:
6.48(w) x 9.56(h) x 1.07(d)

Table of Contents

Introduction

Part I: The Birth of Molecular Biology

1. The Roots of the New Science

2. The One Gene One Enzyme Hypothesis

3. The Chemical Nature of the Gene

4. The Phage Group

5. The Birth of Bacterial Genetics

6. The Crystallization of the Tobacco Mosaic Virus

7. The Role of the Physicists

8. The Influence of the Rockefeller Foundation

9. The Introduction of Physical Techniques

10. The Role of Physics

Part II: The Development of Molecular Biology

11. The Discovery of the Double Helix

12. Deciphering the Genetic Code

13. The Discovery of Messenger RNA

14. The French School

Part III: The Expansion of Molecular Biology

15. Normal Science

16. Genetic Engineering

17. Split Genes and Splicing

18. A New Molecular Biology

19. The Discovery of Oncogenes

20. From DNA Polymerase to the Amplification of DNA

21. Molecular Biology in the Life Sciences

Appendix: Definition of Terms

Notes

Acknowledgments

Index

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