HIV/AIDS and the Nervous System: Handbook of Clinical Neurology (Series Editors: Aminoff, Boller and Swaab)

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This volume provides a comprehensive understanding of HIV/AIDS and neuro-AIDS, including a history of the disease, and an explanation of many of the conditions that can arise in afflicted patients, including opportunistic infections, central nervous system tumors, spinal cord disorders, myopathies and progressive encephalopathy, amongst others.

Clinicians will gain a greater understanding of the complex mechanisms of the disease. Beginning with a basic introduction to HIV infections and Neuro-AIDS, practitioners will find useful data on advances in molecular biology, neuroepidemiology, neuroimaging, neuropathology, neuropharmacology, as well as information on the development of therapeutic strategies appropriate for the disorder, including groundbreaking retroviral therapies.

In addition, the socioeconomic and political constraints that hinder treatment and disease management in developing parts of the world are presented.

• A comprehensive understanding of HIV/AIDS and neuro-AIDS, and the progression of the scientific community’s understanding of the disease
• Detailed information on fields such as neuroepidemiology, neuropathology, neuropharmacology, and neuroimaging and their contributions to HIV/AIDS research
• Subject specific chapters on conditions associated with HIV/AIDS, including opportunistic infections, central nervous system tumors, and myopathies, amongst others

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Product Details

  • ISBN-13: 9780444520104
  • Publisher: Elsevier Science
  • Publication date: 8/31/2007
  • Series: Handbook of Clinical Neurology Series, #85
  • Pages: 384
  • Product dimensions: 7.60 (w) x 10.40 (h) x 1.00 (d)

Meet the Author

Table of Contents

Foreword     vii
List of contributors     ix
Introduction to HIV infection and neuro-AIDS   Peter Portegies   Joseph R. Berger     1
Neuroepidemiology of HIV/AIDS   Robert J. Baumann   Patricio S. Espinosa     3
HIV neurology in the developing world   Gretchen L. Birbeck     33
The neuropathogenesis of HIV-1 infection   James L. Buescher   Sara Gross   Howard E. Gendelman   Tsuneya Ikezu     45
Neurological sequelae of primary HIV infection   Bruce J. Brew     69
AIDS dementia complex   Bruce J. Brew     79
Neurocognitive assessment of persons with HIV disease   Sharron Dawes   Igor Grant     93
HIV myelopathy   Alessandro Di Rocco     123
Peripheral neuropathy in HIV infection   Susama Verma   David M. Simpson     129
Myopathy in HIV infection   Adrian Tien-Auh Chan   Carl Kirton   Lydia Estanislao   David M. Simpson     139
Cerebral toxoplasmosis in AIDS   Lisa M. Chirch   Benjamin J. Luft     147
Cryptococcal infection   Arthur Jackson   William G. Powderly     159
Progressive multifocal leukoencephalopathy   Joseph R. Berger     169
Other opportunistic infections of the central nervous system in AIDS   Bruce A. Cohen   Joseph R. Berger     185
Primary central nervous system lymphoma   Edo Richard   Matthijs C. Brouwer   Peter Portegies     221
Neuroimaging of the HIV/AIDS patient   Curtis A. Given II     229
Cerebrospinal fluid markers in central nervous system HIV infection and AIDS dementia complex   Paola Cinque   Bruce J. Brew   Magnus Gisslen   Lars Hagberg   Richard W. Price     261
The neuropathology of HIV   Benjamin B. Gelman     301
Neuropharmacology of HIV/AIDS   Sidney A. Houff   Eugene O. Major     319
Subject index     369
Color plate section     373
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