HIV and Dementia: Proceedings of the NIMH-Sponsored Conference ''Pathogenesis of HIV Infection of the Brain: Impact on Function and Behavior''by Michael Oldstone (Editor), Ljubisa Vitkovic (Editor)
The principal objective of the book is to inform scientists and educated lay audience of now well-documented involvement of the nervous system in AIDS and the tremendous opportunities for basic neuroscience research in this evolving area. Recent evidence indicates that HIV infection results in the perturbation of the blood-brain barrier potentially facilitating the entry of HIV into the brain parenchyma and directly causing neuronal dysfunction and ultimate death. In addition, recently established models of AIDS in monkeys, cats, and mice faithfully recapitulate aspects of neuropathophysiology of HIV infection in humans thereby providing new opportunities for research in NeuroAIDS.
Description: This book summarizes a 1994 symposium on HIV infection and dementia.
Purpose: The book seeks to be a state-of-the- art review of knowledge of how HIV infection produces dementia.
Audience: This book will appeal primarily to researchers actively investigating dementia in HIV patients.
Features: This book features 17 contributions by researchers in three major areas: HIV dementia in humans, animal models of HIV infection, and in vitro studies of HIV infection.
Assessment: Although up-to-date, this book is limited by a lack of editing or any editorial commentary or oversight. It will be useful to a narrow audience of researchers in the field.
- Springer Berlin Heidelberg
- Publication date:
- Current Topics in Microbiology and Immunology Series , #202
- Edition description:
- Softcover reprint of the original 1st ed. 1995
- Product dimensions:
- 6.10(w) x 9.25(h) x 0.02(d)
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