HIV Neurology / Edition 1

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This text provides a clinical framework for the diagnosis and management of more than seventy potential neurological complications that may occur in the HIV infected patient. The clinical framework is designed to be "user friendly" so that even the most inexperienced clinician should be able to arrive at the correct diagnosis. The neurological complications of HIV disease have considerably changed in the last decade. Not only have more opportunistic conditions been described but other complications arising from antiretroviral drugs such as lipodystrophy and accelerated atherosclerosis have become problematic. Moreover, the pattern of complications has altered. Diseases such as cerebral toxoplasmosis, AIDS dementia complex and primary central nervous system lymphoma are now becoming uncommon to rare while peripheral neuropathy is becoming increasingly common. In line with these changes, there have been very significant advances in the therapy of HIV disease in general and in neurological complications in particular. Patients with AIDS dementia complex now have a variety of antiretroviral and adjuvant drugs available to them in contrast to the situation only five years ago where therapy was confined to two antiretroviral drugs at best.
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Product Details

  • ISBN-13: 9780195133639
  • Publisher: Oxford University Press, USA
  • Publication date: 3/28/2001
  • Series: Contemporary Neurology Series
  • Edition number: 1
  • Pages: 276
  • Product dimensions: 9.80 (w) x 6.80 (h) x 0.70 (d)

Table of Contents

Pt. I Overview
1 Importance of HIV Neurologic Complications to the Neurologist and Physician 3
2 Introduction to HIV Disease 8
3 Principles of HIV Neurology 32
4 Approach to Diagnosis 36
Pt. II Predominantly Nonfocal Complications Relating to the Brain
5 Sequelae of Primary HIV Infection and Nonfocal Complications of Moderately Advanced HIV Disease 45
6 AIDS Dementia Complex 53
7 Cryptococcal Meningitis 91
8 Tuberculous Meningitis 97
9 Uncommon Causes of Nonfocal Brain Disorders in Advanced HIV Disease 101
Pt. III Predominantly Focal Complications Relating to the Brain
10 Focal Brain Disorders in Moderately Advanced HIV Disease: Tuberculosis and Multiple Sclerosis-Like Illness 111
11 Toxoplasmosis 117
12 Primary Central Nervous System Lymphoma and Metastatic Lymphoma 124
13 Progressive Multifocal Leukoencephalopathy 132
14 Seizures 142
15 Cerebrovascular Complications and Transient Neurologic Deficits 146
16 Uncommon Causes of Predominantly Focal Cerebral Complications in Advanced HIV Disease 152
Pt. IV Complications Relating to the Spinal Cord
17 Common Spinal Cord Diseases 165
18 Less Common Complications Causing Spinal Cord Disease in Advanced HIV Infection 174
Pt. V Complications Relating to the Peripheral Nerve
19 Peripheral Nerve Involvement in Early and Moderately Advanced HIV Disease 183
20 Peripheral Neuropathy in Advanced HIV Disease Directly Related to HIV 194
21 Infective Causes of Peripheral Neuropathy in Advanced HIV Disease 202
22 Medication-Related and Nutrition-Related Peripheral Neuropathy 209
Pt. VI Complications Relating to Muscle
23 Myopathy Related to HIV and Opportunistic Conditions 221
24 Medications-Related Myopathy 232
Index 241
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