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Cystic Fibrosis 4E provides everything that the respiratory clinician, pulmonologist or health professional treating patients with cystic fibrosis will need in a single manageable volume. This international and authoritative work brings together current knowledge, and has become established in previous editions as a leading reference in the field.The basic science that underlies the disease and its progression is outlined in detail and put into a clinical context. Diagnostic and clinical aspects are covered in ...
Cystic Fibrosis 4E provides everything that the respiratory clinician, pulmonologist or health professional treating patients with cystic fibrosis will need in a single manageable volume. This international and authoritative work brings together current knowledge, and has become established in previous editions as a leading reference in the field.The basic science that underlies the disease and its progression is outlined in detail and put into a clinical context. Diagnostic and clinical aspects are covered in depth and future developments, including gene therapies and novel therapies, are covered in the concluding section.
Drawing on the expertise of a team of international specialists from a variety of backgrounds,the fourth edition of Cystic Fibrosis is an invaluable reference for respiratory physicians, pediatricians, specialist nurses and other health professionals working with patients with cystic fibrosis.
* Divided into accessible sections reflecting the multi-disciplinary nature ofthe cystic fibrosis care team
* Expanded coverage of clinical areas, including chapters covering sleep, lung mechanics and the work of breathing, upper airway disease, insulin deficiency and diabetes, bone disease, and sexual and reproductive issues
* Covers management in the hospital and at home
* New section on monitoring discusses the use of databases to improve patient care, and covers monitoring in different age groups, exercise testing and the outcomes of clinical trials in these areas.
* Chapters devoted to paramedical issues, including nursing, physiotherapy,psychology, and palliative and spiritual care
New for the fourth edition
Many new chapters including: Living with Cystic Fibrosis, Growing Old with Cystic Fibrosis, Quality Improvement and Outcome of Clinical Trials
Much more information on: Animal models, Infecttion and Inflammation of the airway affected by cystic fibrosis, Management of the screened patient and Pulmonary exacerbations
A new expert and authoritative editorial team with many new international contributors provide a trusted source of information
E book containing many more references, links to pub med, rapid search function, more illustrations and clinical photographs and extra video clips
Newly designed for rapid access to information at a glance.
Introduction - What is CF? Overview (history of CF post discovery of the gene). Epidemiology of Cystic Fibrosis. Living with Cystic Fibrosis: The Voices of Patients and Families. CF Patient with Severe Clinical Course. Parental View. Well CF Adult. Teenager. Screened CF Baby's Parents. Basic Science for the Clinician. Molecular biology of CF, Including CFTR Processing and Functions, and Classes of Mutations. Pathophysiology – Epithelial Cell Biology, ASL, Channel Functions Including Sweat Gland and Pancreas. What Have We Learned from Animal Models? Interactions between Infection and Inflammation in the CF Airway. CFTR and Interactions with Modifier Genes and the Environment: Genotype: Phenotype Correlations and Modifier Genes. CFTR and Interactions with Modifier Genes and the Environment: Environment. Diagnostic Aspects of CF. Diagnosis of the Symptomatic Patient (Excludes Screening) – What Tests, Age Related Presentations, ‘Pre-CF’, CFTR Related Disease. The Screened Patient. Screening: What Tests? Management of the Screened Patient. Microbiology: Laboratory Aspects, Synergy Testing, Infection Control. Microbiology of CF. New Methods for Detecting and Identifying Bacteria. Infection Control. Clinical Aspects of CF. Respiratory Disease – Infection, Clinical Aspects, Include Anti-Inflammatory Therapies, Pulmozyme, Physiotherapy. Pulmonary Exacerbations. Non Infective Respiratory Complications. Sleep, Lung Mechanics and Work of Breathing, Including NIPPV. Delivering Therapy to the CF Lung; Including Intelligent Nebulizers and Dry Powder Devices, Oxygen and Portacaths. Upper Airway Disease. GI Manifestations. Pancreas and GI Excluding Liver. Liver. Insulin Deficiency and Diabetes. Growth and Puberty. Bone Disease. Other CF-Related Disease: Electrolyte Disorders, Skin, Vasculitis, Arthropathy, Teeth, Renal, Eyes, CNS. Sexual and Reproductive Issues. Transplantation. Growing Old with CF. Monitoring. Quality Improvement: Using Databases to Improve Care. Monitoring Tools. Infant and Preschool Lung Function. Role of Bronchoscopy. Clinical Aspects of Imaging the Lungs. Monitoring the Older Child and Adult – Use of Lung Function, Bronchial Challenge, Fitness to Fly, Rates of Growth and Decline of PFTs. Exercise: Testing, and How to Do It. Use in Therapy, Including Role in Bone Management. Outcomes of Clinical Trials. Outcomes of Clinical Trials – Breath, Induced Sputum, Electricity. Imaging the Lungs. LCI. What We Learned over Last. Multi-Disciplinary Care. CF Centre Care (Adults, Paeds, Adolescents, Transition, Home Care and Assessment for Discharge), Including Annual Assessments, OT and Social Work. Nursing. Physiotherapy. Nutritional aspects. Psychology. Palliative and Spiritual Care. CF - the Future. Basic Science – What Will It Deliver: Gene and Stem Cell Therapy. Basic science – What Will It Deliver: Non-Gene Therapy Treatments. The Future - How Will Management Change? Appendices. Appendix A: History of cystic fibrosis. Appendix B: How to manage the screened patient.