Hormone Therapy in Breast and Prostate Cancer / Edition 1

Paperback (Print)
Buy New
Buy New from BN.com
Used and New from Other Sellers
Used and New from Other Sellers
from $54.45
Usually ships in 1-2 business days
(Save 39%)
Other sellers (Paperback)
  • All (9) from $54.45   
  • New (7) from $54.45   
  • Used (2) from $79.73   


In Hormone Therapy in Breast and Prostate Cancer, many of today's leading researchers and clinicians describe the principles underlying targeted hormonal treatments, assess the actions of new and established agents, and illustrate the new applications of hormonal chemoprevention for breast cancer. Topics range from preclinical and clinical antiestrogens to the inhibition of estrogen synthesis and the effects of androgen withdrawal. A wide variety of proven and new agents are discussed-antiestrogens, including aromatase inhibitors (anastrozole, letrozole, and others), SERMs (tamoxifen, raloxifene, and others), and such antiandrogenic strategies as goserelin and bicalutamide.

Read More Show Less

Editorial Reviews

From the Publisher

From the reviews:

"...takes the reader on a fascinating scientific journey that illustrates how the combination of clinical and basic investigations has realized the first two objectives for both of these prevalent malignancies and, with breast cancer, the promise of being close to prevention." -Foreword by Prof. Elwood Jensen, Professor Emeritus, University of Chicago

"This was a well-written and well-thought-out book on extensive and changing subject matter...the chapter on nonsteroidal antiandrogens is one of the best chapters I've read on the subject. It was very well written and covered the subject thoroughly." -The Annals of Pharmacotherapy

"Hormone Therapy in Breast and Prostate Cancer offers an authoritative state-of-the-art account of the role of hormones in prostate and breast cancer...all of the chapters are extremely useful to both researchers and clinicians. " -Trends in Endocrinology & Metabolism

"I highly recommend this volume for all oncologists who treat these patients and for the laboratory investigators who would like to see how their work is translated to the clinic." -Oncology

"...this is an excellent contemporary review of this field. It will be of interest, in particular, to obviously breast surgeons or urologists with an interest in malignancy and, in particular, those involved in clinical trials." -ANZ J. Surg

“This book, a paperback version of a book originally published in 2002, does a good job of chronicling the history of the major developments in hormone therapy for both breast and prostate cancer. … I would have recommended it then to any medicinal chemist or pharmacologist that was just starting breast or prostate cancer research … . can be useful for people looking for a good introduction to hormone therapy … .” (Ross V. Weatherman, ChemMedChem, Vol. 5, 2010)

“The aim of this book is to trace the origin of endocrine therapy in breast and prostate cancer … . Overall the book is more detailed than would be expected and is all the better for it. … This was an interesting book which was much more than the title suggests. It was detailed and the coverage broad giving the reader a wealth of information. The reference lists are very comprehensive … . Overall this is a very useful text.” (Heather M. Wallace, BTS Newsletter, Issue 37, Winter, 2010)

Read More Show Less

Product Details

  • ISBN-13: 9781607614715
  • Publisher: Springer-Verlag New York, LLC
  • Publication date: 9/28/2009
  • Series: Cancer Drug Discovery and Development Series
  • Edition description: Softcover reprint of the original 1st ed. 2002
  • Edition number: 1
  • Pages: 420
  • Product dimensions: 6.10 (w) x 9.10 (h) x 1.10 (d)

Table of Contents

An Introduction to the Regulation of Sex Steroids for the Treatment of Cancer
V. Craig Jordan and Barrington J. A. Furr

Part I. Preclinical Antiestrogens

Antiestrogens and the Cell Cycle
Colin K. W. Watts, Owen W. J. Prall, Jason S. Carroll, Nicholas R. C. Wilcken, Eileen M. Rogan, Elizabeth A. Musgrove, and Robert L. Sutherland

Drug Resistance to Antiestrogens
Ruth M. O'Regan, Anait S. Levenson, Gale M. England, Kathy A. Yao, Henry D. Muenzner, Hiroyuki Takei, and V. Craig Jordan

Mechanisms of Liver Carcinogenesis by Antiestrogens
David H. Phillips

The Effects of Triphenylethylene Antiestrogens on Parameters of Multistage Hepaarcinogenesis in the Rat
Yvonne P. Dragan and Henry C. Pitot

Preclinical Studies of Raloxifene and Related Compounds
Robin Fuchs-Young. Pure Antiestrogens, Alan E. Wakeling

Part II. Antiestrogens: Clinical

Tamoxifen for the Treatment of Breast Cancer
V. Craig Jordan

Clinical Utility of New Antiestrogens
Ruth M. O'Regan and William J. Gradishar

Breast Cancer Prevention with Antiestrogens
Monica Morrow and V. Craig Jordan

Part III. Inhibition of Estrogen Synthesis

Aromatase Inhibitors
Paul E. Goss and Caroline C. Reid

Clinical Utility of Aromatase Inhibitors
K. Shenton, Mitchell Dowsett, and Michael Dukes

LH-RH Agonists for the Treatment of Breast Cancer: Development and Current Status
Roger W. Blamey

Part IV. Androgen and Androgen Withdrawal

Molecular Action of Androgens
Shutsung Liao, Junichi Fukuchi, and Yung-Hsi Kao

Steroidal Antiandrogens
Fritz H. Schröder and Albert Radlmaier

Nonsteroidal Antiandrogens
Geert J. C. M. Kolvenbag and Barrington J. A. Furr

LH-RH Agonist Role in Prostate Cancer Management
Amir V. Kaisary

Part V. Perspective on Progress

Recent Progress in Breast Cancer Research
V. Craig Jordan and Barrington J. A. Furr

Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star


4 Star


3 Star


2 Star


1 Star


Your Rating:

Your Name: Create a Pen Name or

Barnes & Noble.com Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & Noble.com that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & Noble.com does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at BN.com or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation


  • - By submitting a review, you grant to Barnes & Noble.com and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Noble.com Terms of Use.
  • - Barnes & Noble.com reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & Noble.com also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on BN.com. It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)