How Fat Works

How Fat Works

by Philip A. Wood
     
 

ISBN-10: 0674034996

ISBN-13: 9780674034990

Pub. Date: 09/01/2009

Publisher: Harvard University Press


An experimental pathologist and molecular geneticist, Philip Wood uses gene-knockout technology to study the way mouse genes regulate the metabolism of fat—research that provides insights into the workings of fatty-acid metabolism in humans and what can happen when that metabolic balance goes awry. Based on the classes he regularly teaches to first- and

Overview


An experimental pathologist and molecular geneticist, Philip Wood uses gene-knockout technology to study the way mouse genes regulate the metabolism of fat—research that provides insights into the workings of fatty-acid metabolism in humans and what can happen when that metabolic balance goes awry. Based on the classes he regularly teaches to first- and second-year medical students, Wood's book reviews the individual and public health burden of obesity and clarifies often-used, but often inadequately explained, terms employed in the continuing cultural and scientific debate about excess fat. He explains the role of fat in the healthy body, how fat is made, stored, and burned, and demonstrates how excess fat can lead to an array of metabolic disorders and diseases, from hypercholesterolemia and insulin resistance to diabetes. He reviews what recent research can tell us about specific genes or groups of genes that can lead to specific metabolic disorders. He explains the science behind common weight-loss regimens and why those regimens might succeed or fail, and reviews the complex interplay of hormones, genes, and stress in the way our bodies deal with fat through the life cycle. How Fat Works is a concise, clear, and up-to-date primer on the workings of fat, and essential reading for professionals entering careers in medicine and public health administration or anyone wanting a better understanding of one of our most urgent health crises.

Product Details

ISBN-13:
9780674034990
Publisher:
Harvard University Press
Publication date:
09/01/2009
Edition description:
New Edition
Pages:
272
Sales rank:
1,005,295
Product dimensions:
5.60(w) x 8.80(h) x 0.80(d)

Table of Contents

Acknowledgements

Abbreviations

Introduction: Lessons from a mouse

I. The Problem

1. The Burden of Obesity

2. Diseases of Excess Fat

3. Understanding Terms

4. Disorders of Excess Cholesterol and Triglycerides

5. Insulin Resistance and Metabolic Syndrome

6. Type 1 and Type 2 Diabetes

II. How Fat Works

7. The Energy Equation

8. Making and Storing Fat

9. Burning Fat in the Cell

10. Single Gene Disorders of Lipid Metabolism

11. Multifactorial Genetic Disorders of Lipid Metabolism

III. Knowledge into Practice

12. Overcoming Genetics and Aging

13. Breaking the Insulin Cycle

14. Exercise to Burn Fat

15. Lipid-Lowering Drugs

16. Lessons

IV. The Environment

17. Nutrient Labeling

18. Alternative Medicine and Fad Diets

19. Media Coverage of Health Research

Glossary

References

Index

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