Hughes Syndrome: Antiphospholipid Syndrome / Edition 2

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Overview

Eponymous volume – edited by the investigator on the team which defined this syndrome

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Editorial Reviews

Doody's Review Service
Reviewer: Cory B Pittman, MD (Washington University Medical Center)
Description: This is a comprehensive review of the Hughes (anti-phospholipid antibody) syndrome, written and edited by experts in the fields of rheumatology, obstetrics, hematology, and pathology. The book provides a thorough discussion of the basic science, clinical, diagnostic, and therapeutic aspects of the syndrome. The first edition was published in 2000.
Purpose: The purpose was to address the complete range of conditions associated with Hughes syndrome and to provide a reference text for medical professionals in the fields of rheumatology, immunology, hematology, obstetrics, neurology, and dermatology who diagnose and treat the manifestations of this syndrome. Also, to update the 1st edition. Yes, these are worthy objectives. Yes, the book meets the author's objectives.
Audience: According to the author: Trainees and practitioners in the fields of rheumatology, immunology, hematology, obstetrics, neurology, and dermatology. According to my judgment: It is written more for those in the fields of rheumatology, immunology, and hematology. However, practitioners in other fields may also find the book useful. Yes, the authors are credible authorities in the field.
Features: The book covers the basic science, clinical, diagnostic, and therapeutic aspects of Hughes syndrome. The order in which the topics are arranged is very practical. The high quality photographic figures with captions are informative and visually appealing. I like artwork on the hardbound cover. The graphs and tables could be of better quality. They lack visual appeal, and therefore the reader is less likely to spend sufficient time studying them.
Assessment: This book appears to be well-written and well-organized. It is a useful addition to my library, both for its content and as a thorough database of references on the topic of Hughes syndrome. Given the ongoing research and development of new knowledge in this field, the second edition is a welcome update.
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Product Details

  • ISBN-13: 9781852338732
  • Publisher: Springer London
  • Publication date: 12/28/2005
  • Edition description: 2nd ed. 2006
  • Edition number: 2
  • Pages: 598
  • Product dimensions: 5.90 (w) x 9.30 (h) x 1.60 (d)

Table of Contents

1 Hughes syndrome : history 3
2 Antiphospholipid (Hughes) syndrome : an overview 9
3 Epidemiology of antiphospholipid syndrome 22
4 Hemocytopenias in antiphospholipid syndrome 29
5 Cardiac manifestations in antiphospholipid syndrome 41
6 Cerebral ischemia in antiphospholipid syndrome 53
7 Cerebral disease other than stroke and transient ischemic attack in antiphospholipid syndrome 68
8 Skin manifestations of antiphospholipid syndrome 86
9 Kidney disease in antiphosopholipid syndrome 99
10 Systemic hypertension in antiphospholipid syndrome 112
11 Pulmonary hypertension and antiphospholipid antibodies 117
12 Osteoarticular manifestations of antiphospholipid syndrome 127
13 The ear and antiphospholipid syndrome 140
14 The eye in primary antiphospholipid syndrome 147
15 Primary antiphospholipid syndrome 155
16 Catastrophic antiphospholipid syndrome 171
17 Obstetric antiphospholipid syndrome 181
18 Infertility and antiphospholipid antibodies 196
19 Transplantation of solid organs, tissues, and prosthetic devices in patients with antiphospholipid antibodies 209
20 Antiphospholipid syndrome in children 241
21 Ethnic and geographic variation in antiphospholipid syndrome 258
22 Antiphospholipid syndrome : differential diagnosis 264
23 Anticardiolipin testing 275
24 Lupus anticoagulants : mechanistic and diagnostic considerations 291
25 [beta][subscript 2]-glycoprotein I and anti-[beta][subscript 2]-glycoprotein I antibodies 307
26 Antiprothrombin antibodies 319
27 Antiphospholipid syndrome in the absence of standard antiphospholipid antibodies : associations with other autoantibodies 329
28 Vascular pathology of antiphospholipid antibody syndrome 341
29 Placental pathology in antiphospholipid syndrome 362
30 Antiphospholipid syndrome - experimental models : insight into etiology, pathogenesis, and treatments 375
31 Antiphospholipid antibody-induced pregnancy loss and thrombosis 395
32 Mechanism of thrombosis in antiphospholipid syndrome : binding to platelets 403
33 Interaction of antiphospholipid antibodies with endothelial cells 415
34 The influence of antiphospholipid antibodies on the protein C pathway 427
35 Contribution of tissue factor to the pathogenesis of thrombosis in patients with antiphospholipid syndrome 439
36 Annexins in antiphospholipid syndrome 446
37 Plasminogen activation, fibrinolysis, and cell proteolytic activity in antiphospholipid syndrome 457
38 Lessons from sequence analysis of monoclonal antiphospholipid antibodies 470
39 Apoptosis and antiphospholipid antibodies 492
40 Accelerated atherogenesis and antiphosopholipid antibodies 501
41 Genetics of antiphospholipid syndrome 521
42 Infection and drug-induced antiphospholipid antibodies 532
43 Management of thrombosis in antiphospholipid syndrome 547
44 Management of antiphospholipid syndrome in pregnancy 555
45 Management of thrombocytopenia in Hughes syndrome 568
46 The future of Hughes syndrome 579
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