Human Embryology and Developmental Biology: With STUDENT CONSULT Online Access / Edition 4

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This revised fourth edition offers both clear descriptions and explanations of human embryonic development, introducing the reader to major families of important developmental molecules. Clinical aspects of development are covered throughout in boxed sections of text.

This book contains predominantly color illustrations, with some black-and-white illustrations.

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Editorial Reviews

Larry R. Cochard
This new softcover book on embryology is aptly named. It covers normal human development and clinical embryology, with emphasis throughout on relevant molecular and experimental studies. The purpose is to introduce the structural changes in the embryo and fetus in the context of the rapid and revolutionary scientific developments in the field. The stated goal is to do this in a manner that is understandable to the beginning student and streamlined enough for the reduced emphasis on embryology in medical curricula. The book is intended for first-year medical and allied health students. The excellent coverage of clinical topics such as congenital defects, treatment of infertility, prenatal imaging, and the genetic manipulation of embryos will make this appealing to medical students. The detailed coverage of the cellular and molecular basis of development, however, points to a different audience, perhaps graduate students, advanced medical students, or more specialized health professionals. The chapters in the first half of the book emphasize early development, the body plan, mother and fetus, molecular and cellular concepts, and related clinical topics. The second half covers the body systems. The book's unique feature is its focus on the biology of development. No other book in its class has its detail at the molecular and genetic level and its scope. It includes some histology and cell biology, and the descriptive figures on the body systems tend to emphasize more realistic changes in structures instead of schematics. The author does an admirable job on the science of development and the current state of medical embryology, but the detail works against the beginner, at least for a shortembryology course. Although the book may not stand alone for any particular course, it would be an excellent reference for advanced students in a variety of areas in biology and medicine. There is much of value in this unique book.
Combines an introduction to the molecular and mechanistic basis of human development with classic descriptive embryology. Presents the latest findings in the fields of genetics, cell biology, endocrinology, reproduction, pathology, and anatomy, discussing their effect on human developmental biology. Includes review question with answers. Annotation c. Book News, Inc., Portland, OR (
Doody's Review Service
Reviewer: Erin Rae Leslie, PhD (Midwestern University)
Description: The fifth edition of this classic human embryology book includes extensive revisions incorporating updates on human embryology and early development, clinical correlations, review questions, and excellent illustrations. The fourth edition was published in 2008.
Purpose: The goal is to provide up-to-date information on the structures and mechanisms of early human development to medical students and medical professionals. This new edition is justified by the proliferation of new information on many aspects of embryonic development and the molecular regulation of these processes.
Audience: It is most appropriate for medical and graduate students learning embryology and for professionals as a reference.
Features: This book covers in depth the structures and mechanisms of early human embryonic development from the prefertilization period through organogenesis and provides access to the Student Consult website, which includes downloadable full-color illustrations and animated videos showing select developmental processes. The book includes numerous boxed clinical correlations, case vignettes, and review questions with answers. The illustrations are excellent and include several new scanning electron micrographs and clinical case photographs. The revision of chapter 12, on the neural crest, is especially valuable as it effectively consolidates the latest information regarding the complex role of this tissue in development. Grouping the integumentary, skeletal, and muscular systems together in chapter 9 may confuse readers, as these tissues primarily arise from different primordia. The extensive passages on molecular processes and signaling pathways may be daunting to readers lacking a foundation in molecular biology or genetics, and the book would benefit from placing these sections under separate subheadings. In addition, it would be helpful to include chapter information in the page headers, as well as a glossary.
Assessment: This offers well-written, in-depth coverage of early human development that is appropriate for medical and graduate students. A comparable book, Langman's Medical Embryology, 12th edition, Sadler (Lippincott Williams & Wilkins, 2012), covers a similar scope of topics, but is more concise, includes a glossary, and restricts its coverage of molecular-level processes.
From the Publisher
"This is an excellent introduction to classical human embryology from a mechanistic and molecular viewpoint. It fills an important niche at a time when medical educators are faced with a conundrum. The genetic basis of disease and development are becoming more stressed in medicine at the same time that there is decreased coverage of classical embryology in the undergraduate medical curriculum, where it has been subjugated to a few lectures in most anatomy courses. The speed of change in the growing field of molecular and developmental biology warrants this revised and updated version. Overall, it improves upon the third edition it replaces, with improved artwork and the new approach to the development of the head that dental students will find very useful." - Mark Jaffe, DPM, MHSA (Nova Southeastern University), from Doody’s Reviews

"This is an excellent content bridge between anatomy and clinical practice: the vignettes are great and the images from the book are available online and downloadable as slides. It could become a best seller as its content and presentation are excellent, and the web-based support is very good." BMA Book Awards 2009- judges comments

3 Stars from Doody
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Product Details

  • ISBN-13: 9780323053853
  • Publisher: Elsevier Health Sciences
  • Publication date: 11/25/2008
  • Edition description: Older Edition
  • Edition number: 4
  • Pages: 560
  • Product dimensions: 8.50 (w) x 10.80 (h) x 0.70 (d)

Meet the Author

Table of Contents

Developmental Tables

Pt. I Early Development and the Fetal-Maternal Relationship 1

Ch. 1 Getting Ready for Pregnancy 3

Ch. 2 Transport of Gametes and Fertilization 27

Ch. 3 Cleavage and Implantation 43

Ch. 4 Molecular Basis for Embryonic Development 65

Ch. 5 Formation of Germ Layers and Early Derivatives 85

Ch. 6 Establishment of the Basic Embryonic Body Plan 103

Ch. 7 Placenta and Extraembryonic Membranes 131

Ch. 8 Developmental Disorders: Causes, Mechanisms, and Patterns 153

Pt. II Development of the Body Systems 173

Ch. 9 Integumentary, Skeletal, and Muscular Systems 175

Ch. 10 Limb Development 213

Ch. 11 Nervous System 239

Ch. 12 Neural Crest 283

Ch. 13 Sense Organs 299

Ch. 14 Head and Neck 325

Ch. 15 Digestive and Respiratory Systems and Body Cavities 361

Ch. 16 Urogenital System 403

Ch. 17 Cardiovascular System 437

Ch. 18 Fetal Period and Birth 485

Answers to Clinical Vignettes and Review Questions 507

Index 515

Developmentally Important Molecules Mentioned in Text 542

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