Human Gene Mapping, 1995: A Compendium

Human Gene Mapping, 1995: A Compendium

by A. Jamie Cuticchia, Michael A. Chipperfield, Patricia A. Foster
     
 

The current status of the human genome map with information through 8 January 1996 A comprehensive listing of mapped human genes, anonymous DNA segments, and polymorphic markers

In the years since the first Human Gene Mapping Conference in 1973, the number of genes included in the Genome Data Base has reached 5,902. In the past several years, there has been

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Overview

The current status of the human genome map with information through 8 January 1996 A comprehensive listing of mapped human genes, anonymous DNA segments, and polymorphic markers

In the years since the first Human Gene Mapping Conference in 1973, the number of genes included in the Genome Data Base has reached 5,902. In the past several years, there has been enormous growth not only in the numbers of markers localized to the map but also in the speed of the process of placement of such markers. This compendium provides a convenient summary list of markers and abbreviated literature citations to indicate which mapping reagents are available.

While the most current information on the human genome can be obtained via on-line GDB, the annual published reports on the status of the human gene map are a valuable resource for the extensive research community engaged in genetic and physical mapping of the human genome. Starting with the 1993 compendium, this publication has supplanted the previous Chromosome Coordinating Meeting report and the Human Gene Mapping volumes.

Reflecting the editing of the Genome Data Base through 8 January 1996, Human Gene Mapping, 1995 includes (as have the prior publications) the most recent reports of the chromosome mapping committees as well as reports from the nomenclature, comparative mapping, linkage, neoplasia, and clinical disorders committees.

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Editorial Reviews

Doody's Review Service
Reviewer: Roger W. Melvold, PhD (Northwestern University Feinberg School of Medicine)
Description: This is the latest in a series, based on the Genome Data Base (GDB), presenting the status of the human genome map up through 1995. The volume includes a discussion of impending changes in the organization of the GBD, information about electronic access, and contact information for the various commitees responsible for each chromosome, etc.
Purpose: As a measure of the rapid growth in the data resulting from the emphasis on human gene mapping, the edition is 25 percent larger than the 1994 listing. More than 6,200 gene loci/markers are included.
Audience: The volume is directed at geneticists, primarily those involved in human gene mapping.
Features: The data is well organized first in a comprehensive alphabetical listing, then in separate tables for each autosomal chromosome plus the X and Y chromosomes. Additional tables are included for mitochondrial genes, DNA polymorphisms detected by various probes, loci associated with specific human diseases, and chromosomal changes associated with tumor cells. Tables are included to provide information on homology of chromosomal regions between human and mouse, nonhuman primates, and other vertebrates. Each table includes references. There a few black-and-white illustrations.
Assessment: The volume, now being reviewed in late 1996, is already out of date, as is true for all such compendia of rapidly proliferating data, but nevertheless is useful as a reference source for the majority of mapped loci and markers. It should be available in libraries. Individual copies will be useful probably only to those most heavily involved in human gene mapping.
Roger W. Melvold
This is the latest in a series, based on the Genome Data Base (GDB), presenting the status of the human genome map up through 1995. The volume includes a discussion of impending changes in the organization of the GBD, information about electronic access, and contact information for the various commitees responsible for each chromosome, etc. As a measure of the rapid growth in the data resulting from the emphasis on human gene mapping, the edition is 25 percent larger than the 1994 listing. More than 6,200 gene loci/markers are included. The volume is directed at geneticists, primarily those involved in human gene mapping. The data is well organized first in a comprehensive alphabetical listing, then in separate tables for each autosomal chromosome plus the X and Y chromosomes. Additional tables are included for mitochondrial genes, DNA polymorphisms detected by various probes, loci associated with specific human diseases, and chromosomal changes associated with tumor cells. Tables are included to provide information on homology of chromosomal regions between human and mouse, nonhuman primates, and other vertebrates. Each table includes references. There a few black-and-white illustrations. The volume, now being reviewed in late 1996, is already out of date, as is true for all such compendia of rapidly proliferating data, but nevertheless is useful as a reference source for the majority of mapped loci and markers. It should be available in libraries. Individual copies will be useful probably only to those most heavily involved in human gene mapping.
Booknews
The goal of these annual volumes has been to provide a snapshot of the state of the human gene mapping effort up to the time of publication. But the task of compiling and selecting relevant material has become increasingly cumbersome with each year, and the editors suggest that the publication of data in this form should end with this volume and be replaced with a more workable format. The data presented here was current at the end of December 1995 and was extracted from the Genome Data Base version 5.6; now GDB 6.0 makes the database accessible, and editable, via the World Wide Web. Like prior publications, this volume includes the most recent reports of the chromosome mapping committees as well as reports from the nomenclature, comparative mapping, linkage, neoplasia, and clinical disorders committees. Annotation c. Book News, Inc., Portland, OR (booknews.com)

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Product Details

ISBN-13:
9780801853432
Publisher:
Johns Hopkins University Press
Publication date:
01/28/1996
Pages:
1768
Product dimensions:
8.50(w) x 11.00(h) x (d)

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