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Doody's Review ServiceReviewer: Luis F. Escobar, MD, MS (St. Vincent Hospital and Health Care Center)
Description: Masterfully planned with a well-thought-out design, this fourth edition of an extensive compilation of current molecular genetics knowledge is not limited to recent technological advances, but also provides a basic review of concepts in preparation for the introduction of complex information derived from the new molecular genetics science. This is an exhaustive and well done update of the 2004 edition.
Purpose: Recognizing the new era of bioinformatics triggered by the completion of the Human Genome Project, the authors aim to provide an extensive review of human molecular genetics. Their book compiles in an exquisite manner the vast amount of current information on molecular genetics that enables understanding of medical genetic disorders. The authors meet their goals with this wonderful masterpiece.
Audience: Although the authors do not target a specific audience, the information they provide is of use to all genetics professionals, from early clinical students to experienced practitioners, from graduate students to experienced scientists. Teachers in undergraduate education may find this an excellent guide for updating their curriculum.
Features: Logically planned, the book provides basic traditional genetic concepts such as nucleic acid structure and gene expression and transitions slowly to more complex information such as the influence of molecular mechanisms on cell therapy. Chapters begin with key concepts and are filled with wonderful and well-designed illustrations that are both helpful and inviting. Images can be downloaded in different formats from the book's website. The index is complete and it allows easy scanning of the chapters. This book is designed not only to provoke the curiosity of the reader, but also to invite review of the content.
Assessment: This book stands alone as a must have for any genetics professional. The degree of detail and depth of the information is unique. Future editions will be necessary.