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Human Molecular Genetics / Edition 4
     

Human Molecular Genetics / Edition 4

by Tom Strachan, Andrew Read
 

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ISBN-10: 0815341490

ISBN-13: 9780815341499

Pub. Date: 03/31/2010

Publisher: Taylor & Francis

Human Molecular Genetics is an established and class-proven textbook for upper-level undergraduates and graduate students which provides an authoritative and integrated approach to the molecular aspects of human genetics. While maintaining the hallmark features of previous editions, the Fourth Edition has been completely updated. It includes new Key Concepts

Overview

Human Molecular Genetics is an established and class-proven textbook for upper-level undergraduates and graduate students which provides an authoritative and integrated approach to the molecular aspects of human genetics. While maintaining the hallmark features of previous editions, the Fourth Edition has been completely updated. It includes new Key Concepts at the beginning of each chapter and annotated further reading at the conclusion of each chapter, to help readers navigate the wealth of information in this subject.

The text has been restructured so genomic technologies are integrated throughout, and next generation sequencing is included. Genetic testing, screening, approaches to therapy, personalized medicine, and disease models have been brought together in one section. Coverage of cell biology including stem cells and cell therapy, studying gene function and structure, comparative genomics, model organisms, noncoding RNAs and their functions, and epigenetics have all been expanded.

Product Details

ISBN-13:
9780815341499
Publisher:
Taylor & Francis
Publication date:
03/31/2010
Edition description:
New Edition
Pages:
808
Sales rank:
575,298
Product dimensions:
8.30(w) x 10.80(h) x 1.40(d)

Table of Contents

DNA Structure and Gene Expression.
Chromosomes in Cells.
Genes in Pedigrees.
Cell-based DNA Cloning.
Nucleic Acid Hybridization Assays.
PCR, DNA Sequencing and in vitro Mutagenesis.
Organization of the Human Genome.
Human Gene Expression.
Instability of the Human Genome: Mutation and DNA Repair.
Physical and Transcript Mapping.
Genetic Mapping of Mendelian Characters.
Genetic Mapping: Complex Characters.
Genome Projects.
Our Place in the Tree of Life.
Identifying Human Disease Genes.
Molecular Pathology.
Genetic Testing in Individuals and Populations.
Cancer Genetics.
Complex Diseases: Theory and Results.
Studying Human Gene Structure, Expression and Function Using Cultured Cells and Cell Extracts.
Genetic Manipulation of Animals.
Gene Therapy and Other Molecular Genetic-Based Therapeutic Approaches.
Index.

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