Human Virology / Edition 3

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Overview


Viruses are the ultimate parasites: they infect cells and hijack their molecular machinery in order to survive, often destroying the host cell in the process. In so doing, they present a major challenge to human health and well-being, with the continual emergence of new viral strains placing huge demands on healthcare systems internationally.

Human Virology is the perfect introduction to the subject for anyone who needs to understand how viruses impact on human health, and how they can be managed in a clinical context. It does not seek to turn its readers into virologists, but to provide them with enough knowledge of the nature of viruses and viral infections to serve as an essential foundation for anyone encountering viruses in a clinical or biomedical context.

Capturing this complex and rapidly-evolving subject with remarkable clarity, Human Virology describes the general principles of viral biology - the properties of viruses, their replication and genetics - along with disease and resistance, before introducing the infections caused by key groups of viruses. It concludes with an overview of the management of viral disease, including diagnosis and immunization.

Reflecting our latest understanding of the molecular basis of viral diseases, Human Virology is the ideal resource for all students of medicine, dentistry, and the biological and biomedical sciences, who need a clear and focused introduction to the subject.

The Online Resource Centre to accompany Human Virology features figures from the book in electronic format (for registered adopters of the text).

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Editorial Reviews

From the Publisher

"Overall, this is a good solid textbook for use in teaching medical virology. The quality of the figures is excellent and the cost is reasonable for a student. It is always helpful to have an up-to-date virology textbook, since the emergence of new human viruses is occurring constantly. In addition, the techniques used to detect viruses in humans are also rapidly evolving."--Doody's

From The Critics
Reviewer: Rebecca T. Horvat, PhD, D(ABMM)(University of Kansas Medical Center)
Description: This book is intended primarily to provide students with general information about human viral infections. The previous editions were published in 2000 and 1993.
Purpose: It covers the general principles of virus structure and infection mechanisms as well as the epidemiology of viral infections.
Audience: The principal audience includes undergraduate students studying human virology and second year medical students. The book is written in a simple, well organized and straightforward fashion. The authors have used their experiences in the previous editions to enhance and improve the presentation of this material.
Features: The book is arranged into four major sections that cover general principles, specific viral infections, special syndromes, and practical aspects of diagnosing and managing viral infections. At the beginning of each chapter is a detailed outline for easy reference. Many of the chapters contain interesting tidbits, such as the origin of the disease name or the history of the viral discovery. Several chapters discuss special topics such as viral infections that occur in immunocompromised patients, sexual transmission of viruses, and emerging viral infections. The figures are informative and add value to the information presented in the text.
Assessment: Overall, this is a good solid textbook for use in teaching medical virology. The quality of the figures is excellent and the cost is reasonable for a student. It is always helpful to have an up-to-date virology textbook, since the emergence of new human viruses is occurring constantly. In addition, the techniques used to detect viruses in humans are also rapidly evolving.
Doody's Review Service
Reviewer: Rebecca T. Horvat, PhD, D (ABMM)(University of Kansas Medical Center)
Description: This is the fourth edition of a clinical virology book that was last published 18 years ago.
Purpose: It is intended to teach many types of students about the basics of viral diseases in humans. This is a needed update, since many new viruses have been discovered in the last 10 years.
Audience: This would be a good textbook for undergraduate virology students as well as nursing and medical students. The authors display a great deal of expertise in this update.
Features: The book is organized into four sections, beginning with an overview and definition of virology that includes the basic properties of viruses and how they manipulate the host to cause disease. The second section, and the major portion of the book, presents each viral infection in detail. Each of these chapters starts with a diagram illustrating where the specific virus is classified in relation to all viral pathogens and with a clinical case. This includes the type of genome the virus carries and the material that makes up the viral particle. These chapters contain very well-designed charts that summarize the symptoms of each viral syndrome and when virus and antibodies can be detected. At the end of these chapters, a short review recaps the important points. The book continues with chapters on specific clinical syndromes caused by viruses, such as prenatal infections, the effects on the central nervous system, and resurgent or new viral diseases, to name a few. This is followed by the laboratory tests available for the diagnosis of viral infections, immunization, and therapy for viral disease.
Assessment: This is a very good teaching textbook that covers the area of clinical virology in a way that makes it easy to learn. It contains very good graphic descriptions and details that are useful in detecting disease in humans. The authors have interspersed interesting information in each chapter that helps keep readers' interest.
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Product Details

  • ISBN-13: 9780198566601
  • Publisher: Oxford University Press, USA
  • Publication date: 6/28/2006
  • Edition description: Revised Edition
  • Edition number: 3
  • Pages: 328
  • Product dimensions: 10.80 (w) x 8.60 (h) x 0.60 (d)

Meet the Author

Leslie Collier was from 1978 to 1986 Professor of Virology at the London Hospital Medical College, being succeeded in this post by John Oxford. John Oxford is Professor of Virology at St. Bartholomew's and The Royal London School of Medicine and Dentistry at the University of London. He is the co-author of two standard texts on Influenza and Virology and has published 250 scientific papers throughout the world. Professor Oxford serves as the Scientific Director of Retroscreen, Ltd., the College's research virology company.

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Table of Contents

1. Virology: How it all began
2. General properties of viruses
3. Viral replication and genetics
4. How viruses cause disease
5. Resistance to virus infections
6. Viruses and cancer in humans
7. Viruses and the community
8. Upper respiratory tract and eye infections due to adenoviruses, coronaviruses (including SARS CoV), and rhinoviruses
9. Childhood infections caused by paramyxoviruses
10. Orthomyxoviruses and influenza
11. Gastroenteritis viruses
12. Rubella: postnatal infections
13. Parvoviruses
14. Poxviruses
15. Papovaviruses
16. Poliomyelitis and other picornavirus infections
17. The herpesviruses: general properties
18. The alphaherpesviruses: herpes simplex and varicella-zoster
19. The betaherpesviruses: cytomegalovirus and human herpesviruses 6 and 7
20. The gammaherpesviruses: epstein-barr virus and kaposi's sarcoma-assocociated herpesvirus
21. Introduction to the hepatitis viruses
22. The blood-borne hepatitis viruses B and delta
23. The enteric hepatitis viruses A and E
24. The bloodborne hepatitis flaviviruses
25. Retroviruses and AIDS
26. Lyssavirus and rabies
27. Arthropod-borne viruses
28. Exotic and dangerous infections: filoviruses, arenaviruses and hantaviruses
29. Prions and the spongiform encephalopathies
30. Viral diseases of the central nervous system
31. Intrauterine and perinatal infections
32. Viral infections in patients with defective immunity
33. Respiratory Infections
34. Sexually transmitted viral infections
35. Resurgent and emergent viral infections
36. The laboratory diagnosis of viral infections
37. Control of viral diseases by immunization
38. Antiviral chemotherapy

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