Immune Infertility: The Impact of Immune Reactions on Human Infertility / Edition 1

Immune Infertility: The Impact of Immune Reactions on Human Infertility / Edition 1

by Walter K.H. Krause
     
 

ISBN-10: 3642013783

ISBN-13: 9783642013782

Pub. Date: 09/09/2009

Publisher: Springer Berlin Heidelberg

* Written by experienced and acknowledged experts
• Provides a comprehensive overview of immune reactions inducing fertility disorders in both sexes
• Features a reader-friendly structure This comprehensive overview of immune reactions inducing fertility disorders in both sexes first describes the nature and the function of sperm antigens which

Overview

* Written by experienced and acknowledged experts
• Provides a comprehensive overview of immune reactions inducing fertility disorders in both sexes
• Features a reader-friendly structure This comprehensive overview of immune reactions inducing fertility disorders in both sexes first describes the nature and the function of sperm antigens which are capable to induce immune infertility as well as the methods to analyse and characterize these antigens. Secondly, the nature, the origin and induction of antisperm antibodies (ASA) in both sexes and the role of reproductive organs and their interaction with the immune system will be discussed. A large section of the book, which is most important for clinicians working in reproductive medicine, deals with the clinical impact of the immune reaction in reproductive medicine, including the methods of determination and the treatment in immune infertility. Closely related to immune infertility is the development of immune contraceptives which is also discussed.

Product Details

ISBN-13:
9783642013782
Publisher:
Springer Berlin Heidelberg
Publication date:
09/09/2009
Edition description:
2009
Pages:
236
Product dimensions:
6.30(w) x 9.40(h) x 0.60(d)

Table of Contents

Sperm Antigens.- Proteomics of Human Spermatozoa.- Methods of Analysis of Sperm Antigens Related to Fertility.- Sperm Surface Proteomics.- Sperm Functions Influenced by Immune Reactions.- Antisperm Antibodies (ASA).- The Immune Privilege of the Testis.- Immune Chemistry of ASA.- Sperm-Specific T Lymphocytes.- Site and Risk Factors of Antisperm Antibodies Production in the Male Population.- Biologic Substrates Containing ASA.- ASA in the Female.- Sperm-Immobilizing Antibody and Its Target Antigen (CD52).- The Clinical Impact of Sperm Antibodies.- Male Autoimmune Infertility.- Tests for Sperm Antibodies.- Impact on Fertility Outcome.- Sperm Antibodies and Assisted Reproduction.- Treatment of Immune Infertility.- Immune Contraception.- Immunization with Sperm Antigens to Induce Contraception.- Immunocontraception in Wildlife Animals.- Experience from Clinical Trials with Fertility Control Vaccines.

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