Immunology and Aging

Paperback (Softcover reprint of the original 1st ed. 1977)
$82.48
BN.com price
(Save 16%)$99.00 List Price
Other sellers (Paperback)
  • All (2) from $91.93   
  • New (2) from $91.93   
Sending request ...

Product Details

  • ISBN-13: 9781468425437
  • Publisher: Springer US
  • Publication date: 3/22/2012
  • Series: Comprehensive Immunology Series , #1
  • Edition description: Softcover reprint of the original 1st ed. 1977
  • Pages: 228
  • Product dimensions: 7.00 (w) x 10.00 (h) x 0.48 (d)

Table of Contents

1 Biology of Aging: Retrospect and Prospect.- 1. Introduction.- 2. Past Research Activities.- 3. Theories on Mechanisms of Aging.- 4. Present Research Activities.- 5. The Immune System, a Cellular and Molecular Aging Model par Excellence.- 6. Conclusion 6 References.- 2 Cellular Basis of Immunosenescence.- 1. Introduction.- 2. Cellular Environmental Changes.- 3. Cellular Changes.- 4. Concluding Remarks.- References.- 3 The Pathogenic Role of Age-Related Immune Dysfunctions.- 1. The Normal Immune System.- 2. Age-Dependent Immune Dysfunctions.- 3. Age-Related Pathology Due to Immune Dysfunctions.- 4. Summary and Conclusions.- References.- 4 The Immunoepidemiology of Aging.- 1. Summary.- 2. Introduction.- 3. Age-Associated Changes in Primary Lymphoid Organs.- 4. Age-Associated Changes in Indices of Immunity.- 5. Autoantibodies.- 6. Conclusions.- References.- 5 The Thymus and Aging.- 1. Introduction.- 2. Thymus and Endocrine Organs.- 3. Morphology of the Aging Thymus.- 4. The Differentiation Potential of Thymus of Aging Individuals.- 5. The Thymus, Bone Marrow, and Humoral Factors in Aging.- 6. Summary.- References.- 6 Hormones and Aging.- 1. Life Expectancy and Hormonal Environment.- 2. Hormones and the Lymphoid System.- 3. The Impact of Hormones on Aging of the Immune System.- 4. The Impact of Hormone-Lymphocyte Relationship on the Aging Processes.- 5. Conclusions.- References.- 7 Genetic, Developmental, and Evolutionary Aspects of Life Span.- 1. Introduction.- 2. Evolutionary Aspects of Longevity.- 3. Morphogenesis, Cell Program, and Life Span.- 4. Life Shortening Disease States.- 5. Immunogenetic Aspects of Aging.- 6. Summary.- References.- 8 Suppressor Cells in Aging.- 1. Immunological Tolerance.- 2. Antigen Competition.- 3. Effects of Mitogens.- 4. Response to “Thymus Independent Antigens”.- 5. Delayed Type Hypersensitivity.- 6. Esoteria.- 7. Immunoregulation.- 8. The NZB Paradox.- 9. Defining T Cell Subsets Using Antisera Directed Against Ly Differentiation Antigens.- 10. Conclusion.- References.- 9 Attempts to Correct Age-Related Immunodeficiency and Autoimmunity by Cellular and Dietary Manipulation in Inbred Mice.- 1. Introduction.- 2. Histopathology of Autoimmunity Susceptible Mice and Neonatally Thymectomized Mice and Rabbits.- 3. Cellular Engineering to Correct Immunodeficiency, Wasting Disease, and Autoimmunity in Neonatally Thymectomized Mice.- 4. Prevention of Immunodeficiency by Thymus Transplants.- 5. Reversal of Autoimmunity Disease by Cellular Engineering.- 6. Prevention or Delay of Age-Associated Autoimmunity by Genetic Manipulation.- 7. The Decline of Immunologic Vigor with Aging in NZB Mice.- 8. Analysis of Age-Related Immunodeficiencies by Cell Transfer to Irradiated Hosts.- 9. Host Environmental Factors and Aging.- 10. Ecotaxopathy with Aging.- 11. Influence of Nutrition on Decline of Immunity with Aging in NZB Mice.- 12. Increased Longevity of (NZB x NZW)F1 Mice with Calorie Restriction 128 References.- 10 High-Resolution Scanning Electron Microscopy and Its Application to Research on Immunity and Aging.- 1. Introduction.- 2. Sem Techniques.- 3. Cell-Cell Interactions.- 4. Distribution of Specific Receptors on the Surfaces of Young and Senescent Cells.- 5. Membrane Events Following Ligand-Receptor Interaction.- 6. Concluding Remarks.- References.- 11 Immunological Responsiveness and Aging Phenomena in Germfree Mice.- 1. Introduction.- 2. Immune Response in Germfree Mice.- 3. Aging in Germfree Mice.- 4. Aging in Immune Deficient Germfree Mice.- 5. Summary and Conclusions.- References.- 12 Congenitally Athymic (Nude) Mice and Their Application to the Study of Immunity and Aging.- 1. Introduction.- 2. Nature of the Primary Defect.- 3. Natural History of the Nude Mouse.- 4. Immunology of the Nude Mouse.- 5. Diseases Associated with Aging.- 6. Application of the Knowledge of the Nude Mouse to the Aging Problem.- References.- 13 Immunoengineering: Prospects for Correction of Age-Related Immunodeficiency States.- 1. Introduction.- 2. Nutritional Manipulation, Life Span, and Immune Function.- 3. Internal Body Temperature, Aging, and Immune Function.- 4. Reconstitution Experiments with Injected or Grafted Lymphoid Cells.- 5. Thymic Humoral Factors.- 6. Polynucleotides.- References.- Abbreviations.

Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star

(0)

4 Star

(0)

3 Star

(0)

2 Star

(0)

1 Star

(0)

Your Rating:

Your Name: Create a Pen Name or

Barnes & Noble.com Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & Noble.com that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & Noble.com does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at BN.com or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation

Reminder:

  • - By submitting a review, you grant to Barnes & Noble.com and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Noble.com Terms of Use.
  • - Barnes & Noble.com reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & Noble.com also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on BN.com. It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

 
Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)