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Immunology: A Short Course / Edition 4

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New York, NY 2000 Softcover 4th Edition New Condition Brand new Multiple copies available this title. Quantity Available: 4. ISBN: 0471348902. ISBN/EAN: 9780471348900. Inventory ... No: 1560795907. Read more Show Less

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Overview

The field of immunology continues to evolved at a rapid pace, posing significant challenges to medical and graduate students who require a basic knowledge of the fundamentals of the field. Immunology: A Short Course, Third Edition from its initial publication in 1988, has established itself as the single most effective text available for a concise yet comprehensive introduction to immunology and immunologic medicine. Following the dictum of "less is more," the book's tightly organized, reader-friendly presentation has garnered praise from student and practitioner alike. The superbly focused format efficiently synthesizes the field without overwhelming the reader with excessive data or theoretical discussions.

The book contains predominantly color illustrations, with some black-and-white illustrations.

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Editorial Reviews

John A. Robinson
This is the third edition of a simplified monograph on immunology. It has several helpful and somewhat unique features: an extensive glossary of immunologic terms, beautiful color plates of the various types of hypersensitivity reactions, concise summaries, and review questions at the end of each chapter that will be helpful to students. It also contains a less than enthusiastic attempt at a current listing of CD molecules. The purpose of the book, as stated in the initial preface and reiterated in the preface of this third edition, is to ""simplify"" immunology for the medical student. The book is targeted at medical students, but it is probably better suited for advanced undergraduate biology students. Although I believe the authors' hearts were in the right place, I hope that medical school curricula are not going to succumb to the unfortunate trend of dumbing-down of curricula occurring throughout the country. The stated purpose of ""simplification"" predisposed me not to like the book. To my surprise, I came away from it with only mild protestations. The illustrations are of above-average pedagogic value and the concepts are sound. There is, however, much lacking in the areas of mucosal immunology, NK cell physiology, immunologic regulatory mechanisms, and other somewhat revolutionary concepts that will require physician understanding for the care of patients in many specialties in the next few years. Choosing to venture into ""simplified"" autoimmunity and immunodeficiencies is also a mistake. In short, I believe they may have simplified immunology a bit too much. This book will, however, be an outstanding book for an advanced undergraduate biology course.
Booknews
An introduction to immunology, featuring chapter summaries, review questions and explained answers, and a glossary. This fourth edition contains extensive revisions to reflect recent advances in understanding. Special emphasis is placed in this edition on T-and B- cell responses to antigen, antigen processing and presentation, vaccination technology, immunotherapy, and mechanisms of immune disorders. There are also updated case scenarios and review questions, plus new color figures illustrating immune processes. Benjamini is professor emeritus in the department of medical microbiology and immunology at the University of California School of Medicine. Annotation c. Book News, Inc., Portland, OR (booknews.com)
Doody's Review Service
Reviewer: John A. Robinson, MD (Loyola University Stritch School of Medicine)
Description: This is the third edition of a simplified monograph on immunology. It has several helpful and somewhat unique features: an extensive glossary of immunologic terms, beautiful color plates of the various types of hypersensitivity reactions, concise summaries, and review questions at the end of each chapter that will be helpful to students. It also contains a less than enthusiastic attempt at a current listing of CD molecules.
Purpose: The purpose of the book, as stated in the initial preface and reiterated in the preface of this third edition, is to "simplify" immunology for the medical student.
Audience: The book is targeted at medical students, but it is probably better suited for advanced undergraduate biology students.
Features: Although I believe the authors' hearts were in the right place, I hope that medical school curricula are not going to succumb to the unfortunate trend of dumbing-down of curricula occurring throughout the country. The stated purpose of "simplification" predisposed me not to like the book. To my surprise, I came away from it with only mild protestations. The illustrations are of above-average pedagogic value and the concepts are sound. There is, however, much lacking in the areas of mucosal immunology, NK cell physiology, immunologic regulatory mechanisms, and other somewhat revolutionary concepts that will require physician understanding for the care of patients in many specialties in the next few years. Choosing to venture into "simplified" autoimmunity and immunodeficiencies is also a mistake.
Assessment: In short, I believe they may have simplified immunology a bit too much. This book will, however, be an outstanding book for an advanced undergraduate biology course.

2 Stars from Doody
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Product Details

  • ISBN-13: 9780471348900
  • Publisher: Wiley, John & Sons, Incorporated
  • Publication date: 2/28/2000
  • Edition description: Older Edition
  • Edition number: 4
  • Pages: 528
  • Product dimensions: 7.03 (w) x 9.98 (h) x 0.74 (d)

Read an Excerpt

Preface

Since the last edition, significant developments in biomedical research have helped to refine and, in some cases, redefine our understanding of many aspects of the immune system. As a result, every chapter published in the fourth edition has been either updated or rewritten to incorporate new findings and to delete information that no longer reflects current thinking. In addition, several new chapters have been added to the book, including one on cytokines and another on resistance and immunization to infectious diseases. Finally, a new section on experimental systems has been added to Chapter 5. Describing how and why biomedical scientists utilize various experimental tools to investigate the complexities of the immune system is essential to a student's understanding of the subject of immunology.

As in the first three editions, we remain committed to the motto "less is more." Therefore, our objective in creating this edition has been to present what we consider to be the most pertinent material in a concise, palatable, and easily digestible fashion to the introductory student of immunology. Additional supportive material for students and course instructors can also now be found on a Web site (see below).

We are deeply indebted to Dr. Susan Gottesman, who contributed the chapter entitled, "Immunodeficiency and Other Disorders of the Immune System." We also thank Dr. Karen Yamaga, who updated the autoimmunity chapter. The important contributions of Dr. Patricia Giclas, who updated the complement chapter, and Dr. Arturo Casedeval, who added the new final chapter on resistance and immunization to infectious diseases, are also gratefully acknowledged.

Richard Coico would like to acknowledge the loving support of his family during the writing of this book. Their fortitude, inspiration, and enduring patience helped make the job an enjoyable adventure. Special thanks is extended to the following list of colleagues who generously provided their insightful scientific expertise and many helpful suggestions for the Fourth Edition: Drs. Ethan Shevach (NIH), David Margulies (NIH), Lloyd Mayer (Mount Sinai School of Medicine), Lakshmi Tamma (CUNY Medical School), Linda Spatz (CUNY Medical School), Laurel Eckhardt (Hunter College), Kathleen Barnes (Johns Hopkins School of Medicine), Soldano Ferrone (Roswell Park Memorial Institute), and Harriet Robinson (Emory University). Finally, he would like to thank his mentors, Drs. Ronald Curley, Susan Krown, Robert A. Good, and G. Jeanette Thorbecke, each of whom has greatly influenced his commitment and passion to the road taken.

Geoffrey Sunshine would like to thank Peter Brodeur (Tufts University Medical School) and Cindy Theodos (Tufts University Veterinary School) for their unstinting help during the preparation of his section of the current edition; they reviewed chapters in both the Third and Fourth Editions, and offered suggestions for making the material relevant and accessible to introductory readers. He is also grateful to the many friends and colleagues who answered questions about their areas of expertise, especially Mark Exley, Susan Kalled, and Paula Hochman. In addition, he would like to thank his family for their continued support and understanding during the writing.

The authors wish to express their appreciation to the staff members of John Wiley and Sons, Inc., who helped to bring the Fourth Edition to publication and did so with skill, patience, and good humor. Special thanks to our co-workers, including secretaries, office assistants, and other staff members, who helped with the preparation of the manuscript.

Finally, we wish to acknowledge the important contributions made by Dr. Sidney Leskowitz to the earlier editions of this book. The Hypersensitivity chapters are dedicated to his memory.

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Table of Contents

Preface and Acknowledgments to the Third Edition
Preface to the Second Edition
Preface to the First edition
Acknowledgments to the First and Second Editions
Ch. 1 Introduction and Overview
Ch. 2 Elements of Innate and Acquired Immunity
Ch. 3 Immunogens and Antigens
Ch. 4 Antibody Structure
Ch. 5 Biological Properties of Immunoglobulins
Ch. 6 The Genetic Basis of Antibody Structure
Ch. 7 Antigen-Antibody Interactions
Ch. 8 Biology of the B Lymphocyte
Ch. 9 Biology of the T Lymphocyte
Ch. 10 The Role of the Major Histocompatibility Complex in the Immune Response
Ch. 11 Activation of T and B Cells by Antigen
Ch. 12 Control Mechanisms in the Immune Response
Ch. 13 Complement
Ch. 14 Hypersensitivity Reactions: Antibody-Mediated, Type I - Anaphylactic Reactions
Ch. 15 Hypersensitivity Reactions: Antibody-Mediated, Type II - Cytotoxic Reactions and Type III - Immune Complex Reactions
Ch. 16 Hypersensitivity Reactions: T-Cell-Mediated, Type IV - Delayed-Type Hypersensitivity
Ch. 17 Autoimmunity
Ch. 18 Immunodeficiency and Other Disorders of the Immune Response
Ch. 19 Transfusion Immunology
Ch. 20 Transplantation Immunology
Ch. 21 Tumor Immunology
Ch. 22 Immunoprophylaxis and Immunotherapy
Appendix: Partial List of CD Molecules
Glossary
Index
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