Immunology / Edition 5

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The Sixth Edition of Roitt's IMMUNOLOGY brings this classic textbook up to date. 250 top quality photographs and over 400 color illustrations bring immunology to life. Case Studies have been added placing immunology in a clinical context. Expanded Critical Thinking with detailed feedback test understanding and provide a useful revision tool. Part of an unsurpassed coordinated learning package.

The book contains predominantly color illustrations, with some black-and-white illustrations.

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Editorial Reviews

From The Critics
Reviewer: Leslie C. Grammer, MD (Northwestern University Medical School)
Description: This is the fourth edition of a well recognized, classic textbook of immunology. It is authored and edited by recognized authorities in the field, primarily from the U.K. The text covers basic, mechanistic aspects of immunology.
Purpose: The purpose is to make the fascinating subject of immunology understandable to readers at the undergraduate, graduate, and clinical stages of their careers. Because immunology is a rapidly advancing field, this sort of text is essential to provide basic, background information. The book does indeed fulfill the stated objectives.
Audience: The audience for this text would include both graduate and undergraduate students as well as trainees and clinicians in specialties such as allergy, immunology, hematology, and infectious diseases who require extensive knowledge of basic immunologic mechanisms.
Features: This book is an exceptional immunology text because its illustrations are appropriate, colorful, and lucid depictions of the main textual concepts. The references are current and pertinent. The index and table of contents are appropriate. A unique feature of this book is the colorful illustrations of basic immunologic mechanisms and concepts; they result in the attractive overall appearance of the book.
Assessment: Because immunology is a field in which knowledge is expanding exponentially, this new edition is clearly needed. The authors and editors have added two unique features to this edition. At the beginning of each chapter, there is a listing of the key concepts in thechapter, and at the end of each chapter there is a shaded box entitled "critical thinking" that poses questions that could be the basis for in-depth discussion. This is an excellent immunology text with outstanding illustrations. Anyone studying immunology or related fields should have this book available.
A text on immunologic mechanisms for students in science and medicine, featuring color photos and diagrams on every page. Coverage includes the lymphoid system, antigen recognition, regulation of the immune response, the evolution of immunity, and immunological techniques. Contains a glossary, and tables of HLA specificities, CD markers, and cytokines. This fourth edition contains expanded material on T-cell receptors, and MHC molecules, plus chapter objectives and critical thinking boxes. Distributed in the US by Mosby. Annotation c. Book News, Inc., Portland, OR (
An intermediate-level text for students in medicine and science, covering basic science as well as immunology in relation to histology and pathology. Features include color explanatory diagrams, key concepts, frequent paragraph headings, chapter summaries, critical thinking questions, and a glossary. This fifth edition contains revised material throughout to stay abreast of changes in the field over the past two years, with new sections on cytokines, natural killer cells, and intracellular signaling in B and T cells. Coverage of immunodeficiency has been split into two chapters. Supplements include an interactive CD-ROM, case studies, and illustrated outlines. Annotation c. by Book News, Inc., Portland, Or.
From the Publisher
This book is in a relatively easy to read format, colour diagrams help illustrate the concepts in the text and one of the most useful features are the comprehensive summary tables throughout the book. Roitts is a good buy if you are particularly interested in Immunology.
Edinburgh Medics, a Res Medica supplement courtesy of the Royal Medical Society, July 2005
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Product Details

  • ISBN-13: 9780723429180
  • Publisher: Elsevier Health Sciences
  • Publication date: 1/28/1998
  • Edition description: Older Edition
  • Edition number: 5
  • Pages: 423
  • Product dimensions: 8.56 (w) x 11.03 (h) x 0.98 (d)

Meet the Author

Ivan Roitt, MA, DSc, (Oxon) Hon FRCP, (Lond) FRCPath, FRS, Emeritus Professor of Immunology, Director of Institute of Biomedical Science, University College London Medical School, London, UK

Jonathan Brostoff, MA, DM (Oxon), DSc, FRCP (Lond), FRCPath, Professor of Allergy and Environmental Health, Centre for Allergy Research, Department of Immunology, University College London Medical School, London, UK

David Male, MA,PhD, Senior Lecturer in Neuroimmunology, Department of Immunology, Institute of Psychiatry, London, UK

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Table of Contents

1 Introduction to the immune system
2 Cells, tissues and organs of the immune system
3 Cell migration and inflammation
4 Antibodies
5 T-cell receptors and major histocompatibility complex molecules
6 Antigen presentation
7 Cytokines and cytokine receptors
8 Cell cooperation in the antibody response
9 Mononuclear phagocytes in immune defence
10 Cell-mediated cytotoxicity
11 Regulation of the immune response
12 Immunological tolerance
13 Evolution of immunity
14 Immunity to viruses
15 Immunity to bacteria and fungi
16 Immunity to protozoa and worms
17 Vaccination
18 Tumour immunology
19 Primary immunodeficiency
20 Secondary immunodeficiency
21 Hypersensitivity - Type I
22 Hypersensitivity - Type II
23 Hypersensitivity - Type III
24 Hypersensitivity - Type IV
25 Transplantation and rejection
26 Autoimmunity and autoimmune disease
27 Immunological techniques
App. 1 Major histocompatibility complex
App. 2 CD markers
App. 3 The major cytokines
App. 4 Chemokine receptors and chemokines
Explanations for critical thinking and case studies
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