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Doody's Review ServiceReviewer: Michael M. Abecassis, MD (Northwestern University Feinberg School of Medicine)
Description: This book reviews various aspects of the immune system, known immune mechanisms in both allograft and xenograft rejection in several animal and human models of liver transplantation and finally, the clinical aspects of both immunosuppression and rejection in the setting of liver transplantation.
Purpose: The purpose is to bridge the gap between clinical transplanters and immunologists with respect to liver allograft rejection. These are worthy objectives, especially in view of the fact that publications of this nature with particular emphasis on one organ (liver) are not common, thus the book is relevant and needed. The book meets the author's objectives. In addition, it can serve as a valuable reference to the surgeon, the hepatologist, and the pathologist.
Audience: The book is directed at those clinicians involved in the care of liver transplant recipients, both in the short and long terms. The author is a fairly credible authority on this subject matter.
Features: There are sufficient illustrations, especially in the basic immunology review and relating to liver histology. The references are both current and pertinent. Appendixes, indexes, and the table of contents are both user-friendly and helpful. This is an elegant, hardcover book with a good mix of diagrammatic representations for the immunology section and of practical histology for the clinically relevant sections.
Assessment: This book is a timely, relevant synopsis of both theoretical and clinical aspects of the immunology of liver transplantation and represents a good reading source for the clinicians involved in the care of liver transplant recipients. It could be of benefit for individuals, libraries, and bookstores as a resource to those involved in the care of these patients.