Immunology & Serology in Laboratory Medicine / Edition 4

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The 5th edition of this classictext sets the standard for comprehensive coverage of immunology. Building from a solid foundation of knowledge and skills, trusted author Mary Louise Turgeon takes you from basic immunologic mechanisms and serologic concepts to the theory behind the procedures you’ll perform in the lab. Immunology & Serology in Laboratory Medicine, Fifth Editionisthe go-to resource for everything from mastering automated techniques to understanding immunoassay instrumentation and disorders of infectious and immunologic origin. Packed with learning objectives, review questions, step-by-step procedures, and case studies, this text is your key to succeeding in today’s modern laboratory environment.

• Full-color, six-page insert of photomicrographs
provide a better picture of what you’ll see in the laboratory.
Learning objectives at the beginning of each chapter offer a measurable outcome you can achieve by completing the material.
Chapter highlights at the end of each chapter provide a summary of the most important information covered in each chapter.
Review questions at the end of each chapter are tied to learning objectives further enhance your understanding.
Case studies challenge you to apply your knowledge and help strengthen your critical thinking skills.
Glossary at the end of the book provides quick access to key terms and definitions.

• NEW! Expanded chapter on Vaccines
as the importance of vaccines continues to become more evident.
NEW! Updated chapter on Molecular Techniques incorporates the newest technology specific to immunology.
NEW! Key terms at the beginning of each chapter help you learn the important vocabulary in immunology.
NEW! Case studies with added multiple-choice questions in addition to critical thinking questions will help you apply your knowledge and develop critical-thinking skills.

Appropriate for: Medical Laboratory Assistant Students, Medical Technology Students.

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Editorial Reviews

Doody's Review Service
Reviewer: Valerie L. Ng, PhD MD(Alameda County Medical Center/Highland Hospital)
Description: This is the fourth edition of a book encompassing theory, practice, and clinical applications of immunology and serology for clinical laboratory technician (CLT) or scientist (CLS) students and instructors. The previous edition was published in 2003.
Purpose: The author intends this book for CLT or CLS training programs, and as a reference for practicing CLSs or other allied health practitioners interested in this field. These worthy objectives, unfortunately, are not well met by this book.
Audience: Although aimed at CLT or CLS students or practicing CLSs or allied health professionals, the book would also be of interest to anyone curious about these clinical laboratory techniques and applications to diagnosis and disease management. The author is widely recognized for her educational expertise in clinical laboratory science.
Features: This 500-page full size book covers the two immense subjects of immunology and serology. Although the focus is on aspects of these disciplines applicable to the clinical laboratory, the book cannot possibly (and therefore does not) cover all relevant areas. First, the positives — the usual we've come to expect (and thus are spoiled by) from books by this author: clear concise text, clear expectations (learning objectives), standardized and logical chapter layouts, excellent content, great case studies to emphasize teaching points, and appropriate references. All in all, great features for a student textbook. However, here's what I don't like about this book. First, to reiterate, these two subjects are aboslutely immense. Although the author is trying to provide an all-encompassing book for immunology and serology, the reality is that this book skims the surface of these fields. There is inadequate discussion of the medical aspects, and the laboratory assays represent only a subset of those typically ascribed to immunology or serology labs. As an example, there is only one five-page chapter devoted to flow immunocytometry, yet entire textbooks have been devoted to this subject alone. Similarly, entire textbooks have been devoted to each of the clinical laboratory methdologies addressed in this book (e.g., Manual of Molecular and Clinical Laboratory Immunology, 7th edition, Detrick et al. (ASM Press, 2006); Manual of Clinical Microbiology, 9th edition, Murray et al. (ASM Press, 2007), for serological testing; Practical Flow Cytometry, 4th edition, Shapiro (John Wiley, 2003); Modern Blood Banking and Transfusion Practices, 5th edition, Harmening (F. A. Davis, 2005); the Lange series on medical immunology (McGraw-Hill), etc.). The lack of color photographs or photomicrographs for depicting peripheral blood smear findings or physical exam findings of various diseases is disappointing. The black-and-white photos don't have the same impact or teaching effect. The author clearly gave this book idea a good try, but it's not enough to do these burgeoning fields justice.
Assessment: This is a reasonable book to have available for reference and teaching, but unfortunately inadequate to cover laboratory and clinical science theory and technologies in these rapidly evolving areas.
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Product Details

  • ISBN-13: 9780323043823
  • Publisher: Elsevier Health Sciences
  • Publication date: 9/11/2008
  • Edition description: Older Edition
  • Edition number: 4
  • Pages: 544
  • Product dimensions: 8.70 (w) x 11.10 (h) x 1.00 (d)

Table of Contents

1 An Overview of Immunology 3
2 Antigens and Antibodies 15
3 The Cells and Cellular Activities of the Imnune System Granulocytes and mononuclear cells 35
4 The Cells and Cellular Activities of the Immune System Lymphocytes and plasma cells 59
5 Soluble Mediators of the Immune System 89
6 Safety and Basic Techniques in the Immunology-Serology Laboratory 111
7 Agglutination Methods 123
8 Precipitation Methods 131
9 Electrophoresis Techniques 141
10 Labeling Techniques in Immunoassay 151
11 Automated Procedures 159
12 Miscellaneous Techniques 165
13 The Immune Response in Infectious Diseases 173
14 Febrile Diseases 177
15 Streptococcal Infections 185
16 Syphilis 197
17 Lyme Disease 215
18 Cytomegalovirus 227
19 Infectious Mononucleosis 241
20 Hepatitis 253
21 Rubella Infection 275
22 Toxoplasmosis 287
23 Acquired Immunodeficiency Syndrome AIDS 295
24 Hypersensitivity Reactions 317
25 Immunoproliferative Disorders 327
26 Autoimmune Disorders 341
27 Systemic Lupus Erythematosus 367
28 Rheumatoid Arthritis 387
29 Transplantation and Tumor Immunology 399
App. A Chronic Fatigue Syndrome 431
App. B Ehrlichiosis 435
App. C Diagnostic Tests in Medical Laboratory Immunology 437
App. D Immunologic Assays 445
Glossary 461
Index 479
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