Immunomicroscopy: A Diagnostic Tool for the Surgical Pathologist

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Practical, and intended for day-to-day use, this state-of-the-art New Edition presents the elements of immunohistochemistry in the context of the "total test". It deals logically with issues of test selection
  • Offers timely coverage on all diagnostically useful tests and their application and ...
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Overview

Practical, and intended for day-to-day use, this state-of-the-art New Edition presents the elements of immunohistochemistry in the context of the "total test". It deals logically with issues of test selection
  • Offers timely coverage on all diagnostically useful tests and their application and interpretation.
  • Integrates infectious diseases and prognostic markers into each chapter, offering complete diagnostic coverage of any given organ system.
  • Incorporates aspects of molecular morphology throughout.
  • Presents an organ system approach to diagnostic surgical pathology.
  • Includes appendices that address quality assurance and standardization protocols reflecting National Committee for Clinical Laboratory standards guidelines and laser microscopy and digital immunomicroscopy, including image analysis, spectral imaging, and quantitation.
  • Uses full-color illustrations throughout.

With 32 expert contributors.

This book contains predominantly black-and-white illustrations, with some color illustrations.

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Editorial Reviews

Anthony G. Montag
This is a comprehensive review of immunohistochemical methods, available reagents, and their use in diagnostic pathology. The book is intended to serve as a reference work, with copious citations of recent and seminal publications. It provides explanations and clear illustrations of basic techniques in immunomicroscopy. Although primarily directed at the practicing surgical pathologist, the text is also a valuable resource for researchers who need to apply immunoenzyme techniques. The number of useful tables and illustrations is enormous, including a comprehensive listing of the leukocyte antigens as clustered by the last international workshop, illustrations of their expression in leukocyte maturation, and their use in the diagnosis of lymphomas. Comprehensive reviews of intermediate filaments and many other tumor markers are included. Common differential diagnoses are discussed in terms of immunoreactivities. When the first edition appeared in 1986, it was the most comprehensive text on the topic of immunohistochemistry. The second edition has been updated with current references, coverage of new antigens, and reviews of new techniques, yet it retains the clear prose and philosophical style of the original. This second edition remains the most comprehensive reference work on the topic of immunohistochemistry and its application to diagnostic pathology.
From The Critics
Reviewer: Anthony G. Montag, MD (University of Chicago Pritzker School of Medicine)
Description: This is a comprehensive review of immunohistochemical methods, available reagents, and their use in diagnostic pathology.
Purpose: The book is intended to serve as a reference work, with copious citations of recent and seminal publications. It provides explanations and clear illustrations of basic techniques in immunomicroscopy.
Audience: Although primarily directed at the practicing surgical pathologist, the text is also a valuable resource for researchers who need to apply immunoenzyme techniques.
Features: The number of useful tables and illustrations is enormous, including a comprehensive listing of the leukocyte antigens as clustered by the last international workshop, illustrations of their expression in leukocyte maturation, and their use in the diagnosis of lymphomas. Comprehensive reviews of intermediate filaments and many other tumor markers are included. Common differential diagnoses are discussed in terms of immunoreactivities.
Assessment: When the first edition appeared in 1986, it was the most comprehensive text on the topic of immunohistochemistry. The second edition has been updated with current references, coverage of new antigens, and reviews of new techniques, yet it retains the clear prose and philosophical style of the original. This second edition remains the most comprehensive reference work on the topic of immunohistochemistry and its application to diagnostic pathology.

5 Stars! from Doody
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Product Details

Table of Contents

Ch. 1 Principles of Immunomicroscopy 1
Ch. 2 Theoretical and Practical Aspects of the Different Immunoperoxidase Techniques 21
Ch. 3 Fixation, Processing, Special Applications 42
Ch. 4 Lymphoma/Hematopathology: The Antibodies 71
Ch. 5 Lymphoma/Hematopathology: The Diseases 107
Ch. 6 Neuroendocrine and Endocrine Systems 163
Ch. 7 Tumors of the Breast 200
Ch. 8 Gynecologic and Testicular Neoplasms 236
Ch. 9 Prostate, Bladder, and Kidney 256
Ch. 10 Immunohistochemical Detection of Steroid Hormone Receptors 277
Ch. 11 Lung, Pancreas, Colon and Rectum, Stomach, Liver 292
Ch. 12 Immunohistology of the Skin: Melanoma, Intermediate Filament 318
Ch. 13 Diagnostic Immunohistochemistry of the Nervous System 342
Ch. 14 Approach to the "Unknown Primary" - Anaplastic Tumors 368
Ch. 15 Infectious Disease 401
Appendix 1: Staining Protocols and Practical Procedures 417
Appendix 2: Standardization and Quality Control in Immunohistochemistry 425
Appendix 3: Commercial Sources for Antibodies 428
Appendix 4: Commonly Employed Antileukocyte Antibodies by CD Terminology 432
References 435
Index 509
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