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Immunomicroscopy: Volume 19 in the Major Problems in Pathology Series / Edition 3

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Overview

Practical, and intended for day-to-day use, this state-of-the-art New Edition presents the elements of immunohistochemistry in the context of the "total test". It deals logically with issues of test selection · reagent selection and quantification · protocols and methods · controls · results · interpretation · in situ hybridization · reporting · and significance. In each chapter, readers will find infectious diseases and prognostic markers and a molecular morphology perspective, focusing on DNA, RNA, and protein, thus offering the surgical pathologist a genuine ability to see with molecular eyes. Immunomicroscopy, 3rd Edition is Volume 19 in the Major Problems in Pathology Series.
  • Features an expanded authorship of internationally renowned experts.
  • Offers timely coverage on all diagnostically useful tests and their application and interpretation.
  • Integrates infectious diseases and prognostic markers into each chapter, offering complete diagnostic coverage of any given organ system.
  • Incorporates aspects of molecular morphology throughout.
  • Presents an organ system approach to diagnostic surgical pathology.
  • Includes appendices that address quality assurance and standardization protocols reflecting National Committee for Clinical Laboratory Standards guidelines · tissue microarrays · and laser microscopy and digital immunomicroscopy, including image analysis, spectral imaging, and quantitation.
  • Uses full-color illustrations throughout.

With 32 expert contributors.

This book contains predominantly black-and-white illustrations, with some color illustrations.

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Editorial Reviews

From the Publisher
"Intended for daily use, this guide presents the elements of immunohistochemistry in the context of the total test. It deals logically with topics such as test selection, reagent selection and quantification, protocols and methods, controls, results, interpretation, reporting, and significance. Each chapter describes infectious disease and prognostic markers and offers a molecular morphology perspective, focusing on DNA, RNA and protein. This third edition features an expanded authorship of internationally renowned experts and an organ system approach to diagnostic surgical pathology. The appendices address quality assurance and standardization protocols reflecting National Committee for Clinical Laboratory Standards guidelines; tissue microarrays; and laser microscopy and digital immunomicroscopy. Full-color illustrations are used throughout." -- Sci Tech Book News, March 2006
Anthony G. Montag
This is a comprehensive review of immunohistochemical methods, available reagents, and their use in diagnostic pathology. The book is intended to serve as a reference work, with copious citations of recent and seminal publications. It provides explanations and clear illustrations of basic techniques in immunomicroscopy. Although primarily directed at the practicing surgical pathologist, the text is also a valuable resource for researchers who need to apply immunoenzyme techniques. The number of useful tables and illustrations is enormous, including a comprehensive listing of the leukocyte antigens as clustered by the last international workshop, illustrations of their expression in leukocyte maturation, and their use in the diagnosis of lymphomas. Comprehensive reviews of intermediate filaments and many other tumor markers are included. Common differential diagnoses are discussed in terms of immunoreactivities. When the first edition appeared in 1986, it was the most comprehensive text on the topic of immunohistochemistry. The second edition has been updated with current references, coverage of new antigens, and reviews of new techniques, yet it retains the clear prose and philosophical style of the original. This second edition remains the most comprehensive reference work on the topic of immunohistochemistry and its application to diagnostic pathology.
From The Critics
Reviewer: Anthony G. Montag, MD (University of Chicago Pritzker School of Medicine)
Description: This is a comprehensive review of immunohistochemical methods, available reagents, and their use in diagnostic pathology.
Purpose: The book is intended to serve as a reference work, with copious citations of recent and seminal publications. It provides explanations and clear illustrations of basic techniques in immunomicroscopy.
Audience: Although primarily directed at the practicing surgical pathologist, the text is also a valuable resource for researchers who need to apply immunoenzyme techniques.
Features: The number of useful tables and illustrations is enormous, including a comprehensive listing of the leukocyte antigens as clustered by the last international workshop, illustrations of their expression in leukocyte maturation, and their use in the diagnosis of lymphomas. Comprehensive reviews of intermediate filaments and many other tumor markers are included. Common differential diagnoses are discussed in terms of immunoreactivities.
Assessment: When the first edition appeared in 1986, it was the most comprehensive text on the topic of immunohistochemistry. The second edition has been updated with current references, coverage of new antigens, and reviews of new techniques, yet it retains the clear prose and philosophical style of the original. This second edition remains the most comprehensive reference work on the topic of immunohistochemistry and its application to diagnostic pathology.

5 Stars! from Doody
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Product Details

  • ISBN-13: 9780721601823
  • Publisher: Elsevier Health Sciences
  • Publication date: 11/7/2005
  • Series: Major Problems in Pathology Series
  • Edition description: REV
  • Edition number: 3
  • Pages: 624
  • Product dimensions: 7.60 (w) x 10.10 (h) x 1.40 (d)

Table of Contents

1. Principles Of Immunohistochemistry

2. Practical Issues: Fixation, Processing, and Antigen Retrieval

3. Molecular and Special Techniques

4. Lymphoma Including Hodgkin Lymphoma

5. Molecular Morphology in Adrenal and Thyroid Disease

6. Applications Of Immunohistochemistry in Breast Pathology

7. Immunohistochemistry of the Female Reproductive Tract

8. Molecular Morphology and Immunomicroscopy

9. Pediatrics

10. Molecular Morphology of Soft Tissue and Bone

11. Molecular Morphology of The Lung and Mesothelioma

12. Gastrointestinal Tract

13. Immunohistochemistry of Skin Tumors Including Melanocytic Lesions

14. Diagnostic Immunohistochemistry of the Nervous System

15 Anaplastic Tumors: Approach to the ‘Unknown Primary’

16. Cytopathology/FNA

17. Occult Metastasis

Appendices

A. IHC Website

B. Protocols [Immunohistochemistry, Molecular]

C. Standardization/Quality Control

D. Tissue Microarrays

References

Index

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