Immunopathogenesis of HIV Infection

Overview

During the last 5 years, major advances have been made in our understanding of the pathogenesis of human immunodeficiency virus (HIV) disease and in the development of new potent antiviral agents. With regard to HIV pathogenesis, several recent observations have not only changed our perspectives of HIV disease, but have been critical for the design of therapeutic strategies.

The book contains black-and-white illustrations.

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Paperback (Softcover reprint of the original 1st ed. 1997)
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Overview

During the last 5 years, major advances have been made in our understanding of the pathogenesis of human immunodeficiency virus (HIV) disease and in the development of new potent antiviral agents. With regard to HIV pathogenesis, several recent observations have not only changed our perspectives of HIV disease, but have been critical for the design of therapeutic strategies.

The book contains black-and-white illustrations.

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Editorial Reviews

Vijay V. Yeldandi
This is a collection of articles describing the biology of HIV infection and its effect on the human host that reviews the interactions of HIV with constituents of the human immune system. The purpose is to review the research findings relevant to the immunopathogenesis of HIV infection. Basic scientists, students, and other health care professionals involved with the care of patients suffering from HIV disease will benefit from this book. Black-and-white cartoons and several color figures illustrate the text. The references are excellent. Since this is a collection of papers, an index is not necessary, but there is a brief table of contents. Despite being rather concise, this is a very comprehensive text. A superb collection of articles that review the immunopathogenesis of HIV disease make this a wonderful book. It is an excellent resource for students who are interested in understanding HIV infection, basic scientists, and any healthcare professional involved in clinical care of the patient with acquired immunodeficency syndrome. A chapter on vaccines for HIV would have rounded off this excellent book.
Doody's Review Service
Reviewer: Vijay V. Yeldandi, MD (Loyola University Stritch School of Medicine)
Description: This is a collection of articles describing the biology of HIV infection and its effect on the human host that reviews the interactions of HIV with constituents of the human immune system.
Purpose: The purpose is to review the research findings relevant to the immunopathogenesis of HIV infection.
Audience: Basic scientists, students, and other health care professionals involved with the care of patients suffering from HIV disease will benefit from this book.
Features: Black-and-white cartoons and several color figures illustrate the text. The references are excellent. Since this is a collection of papers, an index is not necessary, but there is a brief table of contents. Despite being rather concise, this is a very comprehensive text.
Assessment: A superb collection of articles that review the immunopathogenesis of HIV disease make this a wonderful book. It is an excellent resource for students who are interested in understanding HIV infection, basic scientists, and any healthcare professional involved in clinical care of the patient with acquired immunodeficency syndrome. A chapter on vaccines for HIV would have rounded off this excellent book.

5 Stars! from Doody
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Product Details

  • ISBN-13: 9783642645938
  • Publisher: Springer Berlin Heidelberg
  • Publication date: 12/31/2013
  • Edition description: Softcover reprint of the original 1st ed. 1997
  • Pages: 153
  • Product dimensions: 6.14 (w) x 9.21 (h) x 0.36 (d)

Table of Contents

Contens.- Introduction: Recent advances in the pathogenesis of human immunodeficiency virus infection.- Virologic and immunologic events in primary HIV infection.- The role of viral dynamics in the pathogenesis of HIV disease and implications for antiviral therapy.- Immune dysregulation and CD4+ T cell loss in HIV-1 infection.- Studies on lymphoid tissue from HIV-infected individuals: implications for the design of therapeutic strategies.- Mechanisms of resistance to HIV infection.- HIV-1-specific cytotoxic T lymphocytes and the control of HIV-1 replication.- Noncytolytic CD8 T cell-mediated suppression of HIV replication.- Role of complement and Fc receptors in the pathogenesis of HIV-1 infection.- Simian immunodeficiency virus as a model of HIV pathogenesis.

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