Immunotherapeutic Prospects of Infectious Diseases


The present book focuses on the immunotherapeutic modalities relevant for the induction of enhanced resistance against viral, bacterial, fungal and parasitic infections. New ap-
proaches to vaccination and application of cytokines in in-
fectious diseases are succinctly described. Some novel immu-
nomodulators and their biological properties...
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Paperback (Softcover reprint of the original 1st ed. 1990)
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The present book focuses on the immunotherapeutic modalities relevant for the induction of enhanced resistance against viral, bacterial, fungal and parasitic infections. New ap-
proaches to vaccination and application of cytokines in in-
fectious diseases are succinctly described. Some novel immu-
nomodulators and their biological properties as well as cli-
nicalstudies are presented. Effective enhancement of host defence with a vast array of immunomodulatory agents and re-
combinant cytokines, both in normaland in immunocompromised states, is shown to be an attractive approach. It can func-
tion as an adjunct to present modalities for prevention and control of infectious diseases as well as tumors.
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Product Details

  • ISBN-13: 9783642761225
  • Publisher: Springer Berlin Heidelberg
  • Publication date: 7/31/2012
  • Edition description: Softcover reprint of the original 1st ed. 1990
  • Edition number: 1
  • Pages: 401
  • Product dimensions: 6.14 (w) x 9.21 (h) x 0.86 (d)

Table of Contents

Immunomodulators in Infectious Diseases.- Immunopharmacology of a Class of Synthetics with Therapeutic Potential in Infections and Other Types of Diseases.- Lentinan and its Related Polysaccharides as Host Defence Potentiators: Their Application to Infectious Diseases and Cancer.- Purification and Endotoxin-Like Bioactivities of a Novel Amphiphile from Mycobacterium bovis BCG.- Bacterial Surface Components as Immunomodulators.- Effect of Free and Liposome-Encapsulated MTP-PE on Klebsiella pneumoniae Infection in Mice.- Immunomodulatory Capacity of Drugs Evaluated in a Mouse Model of Klebsiella pneumoniae Infection.- Modulation of Host Resistance by Polymeric Substances from Baptisia tinctoria and Echinacea purpurea.- Antivirals in Treatment of Experimental Bacterial and Fungal Infections.- Influence of Nonspecific Immunomodulation with Thymic Preparations on the Result of Infection in Some Experimental Parasitoses.- In Vitro Influence of Bovine and Human Diacetyl-Splenopentin on Human Peripheral Blood Lymphocytes in Comparison to Thymopentin.- Some Novel Pharmacological Properties of Lentinan.- AIDS.- Status and Current Prospects for the Immunotherapy of Human Immunodeficiency Virus (HIV) Infection.- Biological Activities of Polysaccharides and Those Derivatives Against Cancer and AIDS.- Experience with IMREG-1, a Leukocyte Derived Immunomodulator on Candidiasis and Progression of Disease in Patients with AIDS-Related Complex.- Reduced Replication of Human Immunodeficiency Virus in Promonocytic Cells by Bacterial Immunomodulators and Anti-Retroviral Drugs at an Early Stage of HIV-Infection.- Abrogation of Azidothymidine-Induced Bone Marrow Toxicity by Free and Liposomal Muramyl Dipeptide.- Effectiveness of Diethyldithiocarbamate (DTC, Imuthiol) in Reducing the Incidence of Opportunistic Infections in Patients with AIDS and ARC. A Randomized Placebo Controlled Multicenter Study.- Effects of Synthetic HIV Peptides, Cytokines and Monophosphoryl Lipid A on Chemiluminescence Response.- Host Defence and Immunmodulation.- A Mutual Role of the CNS and Immune System in Host Defence.- The Role of Complement in Host Defence and Immune Response.- Infections, Cancer and Natural Killer Cells.- Polysaccharide Lentinan-Treatment Combined with Inflammatory Agent Augments Antitumor Activity of LAK Cells.- Infiltration of Host Cells in Local Tumor Sites Triggered by the Administration of Anti-Tumor Polysaccharide, Lentinan.- B669 — A Novel Riminophenazine with Potent Phagocyte Activating Properties.- Modulation of Macrophages from Different Anatomical Sites by GF787. Role in Murine Infection with Salmonella typhimurium.- Enhancement of Phagocytic Activity by Desmuramyl Peptide AdDP in Guinea Pig with a Cyclophosphamide-Induced Immunosuppression.- Ex Vivo and in Vitro Effects of Adamantylamide Dipeptide (AdDP) on Macrophages and Lymphocytes.- Effects of Adamantylamide Dipeptide (AdDP) on Cell Mediated Immunity in Vivo.- The Influence of Selected Antimicrobial and Antineoplastic Drugs on Chemiluminescence of Peripheral Granulocytes.- Orally Administered Lectin Stimulates Defence Mechanisms in Humans.- A Study on the Serum Concentration of Lentinan Administered via Various Routes in Tumor Bearing Mice and in Human Breast Cancer Patients: In Relation to Antitumor Effect.- The Role of Oxygen Activated Species in Endotoxin Induced Modulation of Antioxidant Enzymes Activity.- Cytokines.- Protective Activity of MDP-Lys(L 18) and Recombinant Cytokines Against Sendai Virus and Herpes Simplex Virus (HSV) Infections in Mice.- Activation of Phagocytes by Recombinant Interferon-?.- Poly A-Poly U: An Updated Review.- Interaction of Rat Macrophages with Leishmania infantum: Role of Tumor Necrosis Factor.- Pretreatment of Mice with GF787, a Fraction of Propionibacterium acnes,Enhances Macrophage Resistance to Leishmania infantum.- Recombinant Interferon in Treatment of Infectious Diseases of Central Nervous System in Newborns.- Polysaccharide-Protein Complexes as BRMs in Septic Shock.- Decrease of the Proportion of HLA-DR+ Monocytes as Prognostic Parameter for the Clinical Outcome of Septic Disease.- Vaccines, Adjuvants and Antibodies.- The Challenge of Chronic and Persisting Infections for Vaccine Development.- Needs for New Vaccines and Improved Immunization Schedules.- ISCOMS: Application in Infectious Diseases.- Role of Adjuvants in Malaria Vaccines.- Cytokines — The New Generation of Adjuvants for Vaccines?.- Effect of Adamantylamide Dipeptide on Antibody Response to Influenza Subunit Vaccines and Protection Against Aerosol Influenza Infection.- Immunomodulatory Effects of Influenza Subunit Vaccine Adjuvantized with Adamantylamide Dipeptide (AdDP) or its Constituent Components.- Some Immunopharmacological Properties of Adamantylamide Dipeptide (AdDP).- Idiotypic Vaccines: Role of Network Antigen.- The Role of Human Monoclonal Antibody Specificity and Avidity in the Protection Against Gram-negative Bacteria.- Anti-Bacterial Reactivity of Human Monoclonal Polyspecific Natural IgM Antibodies — a Basic Defence. Mechanism Against Infectious Agents.- Suppression of Virus Reproduction by Hydrophobized Antibodies Against Viral Proteins.- Respecrin — a New Approach to Constructing Drugs with Targeted Action.- New Approaches to Vaccination against Icterohaemorrhagiae Leptospirosis.
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