Immunotoxicology and Risk Assessment / Edition 1

Immunotoxicology and Risk Assessment / Edition 1

by Dennis K. Flaherty
     
 

ISBN-10: 030645971X

ISBN-13: 9780306459719

Pub. Date: 05/31/1999

Publisher: Springer US

This authored book presents basic immunological tenets and mechanisms at the cellular and molecular level while employing the toxicology foc us on hazard identification, appropriate assays, dose response, and ri sk assesment by mathematical models and safety factors. It will be a u seful reference to toxicologists because it will incorporate new guide lines that

Overview

This authored book presents basic immunological tenets and mechanisms at the cellular and molecular level while employing the toxicology foc us on hazard identification, appropriate assays, dose response, and ri sk assesment by mathematical models and safety factors. It will be a u seful reference to toxicologists because it will incorporate new guide lines that the EPA is bringing out later this year for all chemicals r egulated under the Federal Insecticide, Fungicide, and Rodenticide Act and the Toxic Substances Control Act. Regulatory sections in each cha pter focus on data from both the US Food and Drug Administration, as w ell as data applicable to western European Nations.

Product Details

ISBN-13:
9780306459719
Publisher:
Springer US
Publication date:
05/31/1999
Edition description:
1999
Pages:
382
Product dimensions:
6.10(w) x 9.25(h) x 0.04(d)

Table of Contents

to Immunotoxicology.- Innate Immunity.- Cells of the Immune System.- Immunogenicity and Antigenicity.- Antigen-Presenting Cells.- Antigen Presentation.- Surface Interactions and Intracellular Signaling.- B-Cell Activation.- Antibodies.- Immunological Memory.- Complement.- Phagocytosis and Intracellular Killing.- Immediate Hypersensitivity Reactions.- Autoimmunity.- Delayed Hypersensitivity Reactions.- Killer Cells.- Killer Cells and Viral Infections.- Transplantation.- The Kines.- Assessment of Biological Significance.- Risk Characterization.- References.

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