In Pursuit of the Gene: From Darwin to DNA

In Pursuit of the Gene: From Darwin to DNA

by James Schwartz
ISBN-10:
0674034910
ISBN-13:
9780674034914
Pub. Date:
03/30/2010
Publisher:
Harvard University Press
ISBN-10:
0674034910
ISBN-13:
9780674034914
Pub. Date:
03/30/2010
Publisher:
Harvard University Press
In Pursuit of the Gene: From Darwin to DNA

In Pursuit of the Gene: From Darwin to DNA

by James Schwartz
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Overview

The mystery of inheritance has captivated thinkers since antiquity, and the unlocking of this mystery—the development of classical genetics—is one of humanity’s greatest achievements. This great scientific and human drama is the story told fully and for the first time in this book.

Acclaimed science writer James Schwartz presents the history of genetics through the eyes of a dozen or so central players, beginning with Charles Darwin and ending with Nobel laureate Hermann J. Muller. In tracing the emerging idea of the gene, Schwartz deconstructs many often-told stories that were meant to reflect glory on the participants and finds that the “official” version of discovery often hides a far more complex and illuminating narrative. The discovery of the structure of DNA and the more recent advances in genome science represent the culmination of one hundred years of concentrated inquiry into the nature of the gene. Schwartz’s multifaceted training as a mathematician, geneticist, and writer enables him to provide a remarkably lucid account of the development of the central ideas about heredity, and at the same time bring to life the brilliant and often eccentric individuals who shaped these ideas.

In the spirit of the late Stephen Jay Gould, this book offers a thoroughly engaging story about one of the oldest and most controversial fields of scientific inquiry. It offers readers the background they need to understand the latest findings in genetics and those still to come in the search for the genetic basis of complex diseases and traits.


Product Details

ISBN-13: 9780674034914
Publisher: Harvard University Press
Publication date: 03/30/2010
Edition description: New Edition
Pages: 384
Product dimensions: 6.00(w) x 9.10(h) x 1.00(d)

About the Author

James Schwartz is an independent scholar and writer living in Brookline, Massachusetts.

Table of Contents

List of Illustrations

Preface

1. Viva Pangenesis

2. Reversion to the Mean

3. Galton's Disciples

4. Pangenes

5. Mendel

6. Rediscovery

7. Mendel Wars I

8. Cell Biology

9. Sex Chromosomes

10. The Fly Room

11. Oenothera Reconsidered

12. X-rays

13. Mendel Wars II

Epilogue

Notes

Index

What People are Saying About This

In Pursuit of the Gene is far better than anything now in print for the generalist reader.Schwartz knows the literature on the history of genetics well and he is good at explaining what can sometimes be very abstruse scientific arguments clearly. Even the statistical sections are crystal clear. All of this is conveyed to the specialist reader with a light touch—while at the same time managing not to overwhelm the generalist reader.



Adam Hochschild. author of Bury the Chains and Kin Ghost

This is science for the intelligent general reader as it ought to be written and seldom is: where the scientists are flesh and blood human beings who struggle, fail, compete, rejoice, despair, go down wrong paths and finally stumble, in stages, upon a radically new way of seeing the natural world. A fascinating and readable odyssey that ranges from Texas to Holland to Stalin's prisons and reminds us how hard-won scientific knowledge is.

Janet Browne

In this sparkling and timely book James Schwartz reveals the remarkable history of the gene from its nineteenth-century origins as an entirely imaginary concept to the modern belief that life itself rests in these awe-inspiring combinations of molecules. Accurate, lively, and packed full with incident, this book is a triumph of science writing. --(Janet Browne, author of Charles Darwin: Voyaging and Charles Darwin: The Power of Place)

Elof Carlson

In Pursuit of the Gene is magnificent and captivating in its use of largely unpublished correspondence to reveal scientists as human beings with feelings, intrigue and emotions riding high. --(Elof Carlson, Distinguished Teaching Professor Emeritus, Stony Brook University)

Matthew Meselson

Through his careful reading of original sources, many previously ignored or unknown, biologist-mathematician-science writer James Schwartz has produced a superb history of the gene and the chromosomes -- from Darwin, Galton, Mendel and the early cell-biologists up to the discovery of the DNA double helix.


--(Matthew Meselson, Thomas Dudley Cabot Professor of the Natural Sciences, Harvard University)

David Altshuler

In Pursuit of the Gene is a wonderful book, and arrives at just the right time. With genetic discoveries being made on a daily basis, Schwartz's book deserves a wide readership and attention.
--(David Altshuler, Director, Broad Institute's Program in Medical and Population Genetics)

Adam Hochschild

This is science for the intelligent general reader as it ought to be written and seldom is: where the scientists are flesh and blood human beings who struggle, fail, compete, rejoice, despair, go down wrong paths and finally stumble, in stages, upon a radically new way of seeing the natural world. A fascinating and readable odyssey that ranges from Texas to Holland to Stalin's prisons and reminds us how hard-won scientific knowledge is. --(Adam Hochschild. author of Bury the Chains and King Leopold's Ghost)

Ruth Schwartz

In Pursuit of the Gene is far better than anything now in print for the generalist reader.Schwartz knows the literature on the history of genetics well and he is good at explaining what can sometimes be very abstruse scientific arguments clearly. Even the statistical sections are crystal clear. All of this is conveyed to the specialist reader with a light touch—while at the same time managing not to overwhelm the generalist reader.


--(Ruth Schwartz Cowan, Janice and Julian Bers Professor, University of Pennsylvania)

Ruth Schwartz Cowan

In Pursuit of the Gene is far better than anything now in print for the generalist reader.Schwartz knows the literature on the history of genetics well and he is good at explaining what can sometimes be very abstruse scientific arguments clearly. Even the statistical sections are crystal clear. All of this is conveyed to the specialist reader with a light touch—while at the same time managing not to overwhelm the generalist reader.

Ruth Schwartz Cowan, Janice and Julian Bers Professor, University of Pennsylvania

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