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In Search of Memory: The Emergence of a New Science of Mind
“A stunning book.”—Oliver Sacks
Memory binds our mental life together. We are who we are in large part because of what we learn and remember. But how does the brain create memories? Nobel Prize winner Eric R. Kandel intertwines the intellectual history of the powerful new science of the mind—a combination of cognitive psychology, neuroscience, and molecular biology—with his own personal quest to understand memory. A deft mixture of memoir and history, modern biology and behavior, In Search of Memory brings readers from Kandel's childhood in Nazi-occupied Vienna to the forefront of one of the great scientific endeavors of the twentieth century: the search for the biological basis of memory.
1102648622
In Search of Memory: The Emergence of a New Science of Mind
“A stunning book.”—Oliver Sacks
Memory binds our mental life together. We are who we are in large part because of what we learn and remember. But how does the brain create memories? Nobel Prize winner Eric R. Kandel intertwines the intellectual history of the powerful new science of the mind—a combination of cognitive psychology, neuroscience, and molecular biology—with his own personal quest to understand memory. A deft mixture of memoir and history, modern biology and behavior, In Search of Memory brings readers from Kandel's childhood in Nazi-occupied Vienna to the forefront of one of the great scientific endeavors of the twentieth century: the search for the biological basis of memory.
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In Search of Memory: The Emergence of a New Science of Mind
Memory binds our mental life together. We are who we are in large part because of what we learn and remember. But how does the brain create memories? Nobel Prize winner Eric R. Kandel intertwines the intellectual history of the powerful new science of the mind—a combination of cognitive psychology, neuroscience, and molecular biology—with his own personal quest to understand memory. A deft mixture of memoir and history, modern biology and behavior, In Search of Memory brings readers from Kandel's childhood in Nazi-occupied Vienna to the forefront of one of the great scientific endeavors of the twentieth century: the search for the biological basis of memory.
Eric R. Kandel is Kavli Professor and University Professor at Columbia University and senior investigator at the Howard Hughes Medical Institute. He received the Nobel Prize in Physiology or Medicine in 2000. He lives in New York City.
Table of Contents
Preface xi 1 Personal Memory and the Biology of Memory Storage 3 A Childhood in Vienna 12 An American Education 33 2 One Cell at a Time 53 The Nerve Cell Speaks 74 Conversation Between Nerve Cells 90 Simple and Complex Neuronal Systems 103 Different Memories, Different Brain Regions 116 Searching for an Ideal System to Study Memory 135 Neural Analogs of Learning 150 3 Strengthening Synaptic Connections 165 A Center for Neurobiology and Behavior 180 Even a Simple Behavior Can Be Modified by Learning 187 Synapses Change with Experience 198 The Biological Basis of Individuality 208 Molecules and Short-Term Memory 221 Long-Term Memory 240 Memory Genes 247 A Dialogue Between Genes and Synapses 261 4 A Return to Complex Memory 279 Synapses Also Hold Our Fondest Memories 286 The Brain's Picture of the External World 295 Attention Must Be Paid! 307 5 A Little Red Pill 319 Mice, Men, and MentalIllness 335 A New Way to Treat Mental Illness 352 Biology and the Renaissance of Psychoanalytic Thought 363 Consciousness 376 6 Rediscovering Vienna via Stockholm 393 Learning from Memory: Prospects 416 Glossary 431 Notes and Sources 453 Acknowledgments 485 Index 489