In Vitro Toxicity Testing Protocols

In Vitro Toxicity Testing Protocols

by Sheila O'Hare, Christopher K. Atterwill
     
 

In Vitro Toxicity Testing Prools is a collection of proven, state-of-the-art methods that toxicologists can use in carrying out laboratory studies. The book's expert contributors offer a variety of efficient in vitro toxicology techniques that can be applied regularly in your lab, or can serve as the fundamental basis for the establishment of novel techniques in

Overview

In Vitro Toxicity Testing Prools is a collection of proven, state-of-the-art methods that toxicologists can use in carrying out laboratory studies. The book's expert contributors offer a variety of efficient in vitro toxicology techniques that can be applied regularly in your lab, or can serve as the fundamental basis for the establishment of novel techniques in working laboratories. All the procedures are highly reliable.

Also included are ex vivo techniques, whose development embraces the twin aims of reduction and refinement of the use of laboratory animals; the editors believe this is an important step toward the ethical treatment of laboratory animals.

In keeping with the successful format of preceding volumes of the Methods in Molecular Biology series, concise, easy-to-follow, step-by-step prools are provided for each technique, together with extensive notes that cover troubleshooting and offer special tips to ensure the successful completion of your experiments.

Editorial Reviews

4 Stars! from Doody
Roberto A. Matamoros
This book provides an excellent presentation of the recent advances made in in vitro toxicology. Contributing authors place these advances in a meaningful perspective and present the material in easy-to-follow protocols. These protocols are designed to provide a collection of proven methods on in vitro toxicity testing. They present the scientific aspects of this complex and important area of toxicology and will be a valuable source of information for all those working in this field. This book will serve the needs of scientists in the field of regulatory and research toxicology, including toxicologists, pathologists, and pharmacologists in industry, medicine, contract laboratories, and academia. This book presents the material with brevity, minimal use of jargon, and accuracy. The quality and pertinence of illustrations are appropriate. It presents practical references including recent publications. At the end of each chapter there is a useful section of notes with comments that cover troubleshooting and offer tips on how to get the best results from this techniques. This is a very good reference book for scientists in the field of in vitro toxicology. The authors succeeded in their efforts to fill the need for current knowledge on this subject. The introductory chapter on alternative tests for evaluating toxicity is especially useful in the areas of compound development, validation issues, and opportunities for the future in this important field of toxicology.
Booknews
A collection of techniques that toxicologists can apply in the lab or use as the basis for establishing new methods. Includes some ex vivo techniques to help reduce and refine the use of lab animals. Sections focus on: target organ toxicity, general and topical toxicity, irritancy testing, immunotoxicity, carcinogenesis, and submammalian and subvertebrate models for teratogenicity testing. Comb-binding. Annotation c. Book News, Inc., Portland, OR (booknews.com)
Doody's Review Service
Reviewer: Roberto A. Matamoros, DVM, PhD (University of Illinois at Chicago College of Medicine)
Description: This book provides an excellent presentation of the recent advances made in in vitro toxicology. Contributing authors place these advances in a meaningful perspective and present the material in easy-to-follow protocols.
Purpose: These protocols are designed to provide a collection of proven methods on in vitro toxicity testing. They present the scientific aspects of this complex and important area of toxicology and will be a valuable source of information for all those working in this field.
Audience: This book will serve the needs of scientists in the field of regulatory and research toxicology, including toxicologists, pathologists, and pharmacologists in industry, medicine, contract laboratories, and academia.
Features: This book presents the material with brevity, minimal use of jargon, and accuracy. The quality and pertinence of illustrations are appropriate. It presents practical references including recent publications. At the end of each chapter there is a useful section of notes with comments that cover troubleshooting and offer tips on how to get the best results from this techniques.
Assessment: This is a very good reference book for scientists in the field of in vitro toxicology. The authors succeeded in their efforts to fill the need for current knowledge on this subject. The introductory chapter on alternative tests for evaluating toxicity is especially useful in the areas of compound development, validation issues, and opportunities for the future in this important field of toxicology.

Product Details

ISBN-13:
9781489940827
Publisher:
Springer-Verlag New York, LLC
Publication date:
04/30/2014
Series:
Methods in Molecular Biology Series, #43
Edition description:
1995
Pages:
332
Product dimensions:
5.98(w) x 9.02(h) x 0.03(d)

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