In Vivo Immunology: Regulatory Processes during Lymphopoiesis and Immunopoiesis

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Proceedings of the July 1993 conference dedicated to in vivo immunology and cellular, functional, and molecular aspects of the lymphoid system. Papers feature new data and hypotheses related to non-lymphoid effector and regulatory cells, cell traffic, and the emerging field of neuroendocrine-immune interactions. Other topics include AIDS, MALT, lympho- and immunopoiesis of B and T cells, and dysregulatory aspects of the immune system. Annotation c. Book News, Inc., Portland, OR (
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Product Details

  • ISBN-13: 9781461360629
  • Publisher: Springer US
  • Publication date: 4/30/2013
  • Series: Advances in Experimental Medicine and Biology Series, #355
  • Edition description: Softcover reprint of the original 1st ed. 1994
  • Edition number: 1
  • Pages: 311
  • Product dimensions: 7.00 (w) x 10.00 (h) x 0.71 (d)

Table of Contents

Analysis by In Situ Hybridization of Cytokine mRNAS Expression in Thymic Nurse Cells 1
Genetic Expression of the C-CBL Proto-Oncogene in Human Thymocytes 9
Production and Selection of B Lymphocytes in Bone Marrow: Lymphostromal Interactions and Apoptosis in Normal, Mutant and Transgenic Mice 15
Thymic Neuroendocrine Self Peptides and T Cell Selection 21
Human Fetal Liver Cells Differentiate into Thymocytes in Chimeric Mouse Fetal Thymus Organ Culture 27
Towards Identification of Memory B Cells in Human Tonsils 33
Prolonged IL-4 Treatment Decreases the TNP-Specific Memory Formation for IgG[subscript 1] 39
Selection of Anti-Arsonate Idiotype (CRIA) in A/J Mice by the Immune Network 45
The Life History and Functional Roles of Accessory Cells 51
The Role of Macrophages in Regeneration of Splenic Tissue after Autologous Transplantation in Rat 57
In Vivo Antigen Presentation Capacity of Dendritic Cells from Oral Mucosa and Skin Draining Lymph Nodes 63
Liposome Mediated Modulation of Macrophage Functions 69
In Vivo gp39-CD40 Interactions Occur in the Non-Follicular Compartments of the Spleen and Are Essential for Thymus Dependent Antibody Responses and Germinal Center Formation 75
The Role of Dendritic Cells in the Uptake and Presentation of Oral Antigens 81
Blockage of Thymic Medullary Epithelial Cell Activation: In Vivo Consequences 87
Half-Lives of Antigen/MHC Class II Complexes Differ between Distinct Organ Microenvironments 93
Regulation of Neural and Peripheral Cytokine Production by Benzodiazepines and Endogenous Anxiogenic Peptides 101
Could ACTH be of Prime Importance in Rapidly Altering the Thymocyte Composition in the Thymus? 107
Adrenergic and Cholinergic Regulation of Apoptosis and Differentiation of Thymic Lymphocytes 113
Autoimmune lpr and gld Mice: Models of Abnormal Adhesion Molecule Regulation and Defective Lymphocyte Traffic 119
Vascular Addressin Expression in Peyer's Patches: An in Vivo Study of Site-Associated Regulation 125
Domain 5 of the Intercellular Adhesion Molecule-1 (ICAM-1) Is Involved in Adhesion of B-Cells and Follicular Dendritic Cells 131
Modifications of the Expression of Homing and Adhesion Molecules in Infiltrated Islets of Langerhans in Nod Mice 137
Characterization of Giant Perivascular Spaces in the Thymus of the Nonobese Diabetic Mouse 143
Adhesion Molecule PECAM-1/CD31 Is Expressed on Defined Subsets of Murine LAK Cells 147
Intrathymic Gap Junction-Mediated Communication 155
Complement and Antibody Enhance Binding and Uptake of HIV-1 by Bone Marrow Cells 159
Follicular Dendritic Cells (FDC) Are Not Productively Infected with HIV-1 in Vivo 165
Lymph Node Pathology in Experimental FIV Infection 169
Lymphocyte Lifespan in Murine Retrovirus-Induced Immunodeficiency 177
Analysis of HIV Infections in Human Macrophage-Like Cell Lines 183
The Pivotal Role of the Immunoglobulin Receptor of Tumor Cells from B Cell Lymphomas of Mucosa Associated Lymphoid Tissue (MALT) 189
TNF[alpha]-Is Involved in the Mechanism of Murine Thymic Lymphoma Prevention by Bone Marrow Grafting 195
Analysis of Germinal Centres in the Immune Response to Oxazolone 201
Cytokine Responsiveness of Germinal Center B Cells 207
The Differences in Survival and Phenotype between Centroblasts and Centrocytes 213
In Vivo Localisation Patterns and Cell-Cell Interactions of Cytokine Producing T-Cells and Specific Antibody Forming B-Cells 219
DHEAS Enhances Germinal Center Responses in Old Mice 225
Cellular Origin of Follicular Dendritic Cells 231
Germinal Centers Develop at Predilicted Sites in the Chicken Spleen 237
Expression and Function of DRC-1 Antigen 243
The Appendix Functions as a Mammalian Bursal Equivalent in the Developing Rabbit 249
Development of Components of the Mucosal Immune System in SCID Recipient Mice 255
Many Newly Formed T Lymphocytes Leave the Small Intestinal Mucosa via Lymphatics 261
Analysis of IgA-Producing Hybridomas Derived from Peritoneal B1 Cells 265
Modulation of the Neonatal IgA Response to Enteric Antigens by Maternal Antibody 271
Antibody-Forming Cells (AFCs) in the Lung Lymphoid Tissue after Primary and Secondary Immunization through Different Routes: A Semiquantitative Analysis in Adult Rats Using T-Dependent (TNP-KLH) and T-Independent Antigens (TNP-LPS) 277
Non-Lymphoid Cells in Acute and Chronic Experimental Inflammatory Bowel Disease 283
Five Human Mature B Cell Subsets 289
Absence of EGF Receptors and of EGF Uptake in Peyer's Patch Dome Epithelium 295
Place of Malt in the Immune Defence System 303
Index 309
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