Industrial Proteomics: Applications for Biotechnology and Pharmaceuticals / Edition 1

Industrial Proteomics: Applications for Biotechnology and Pharmaceuticals / Edition 1

by Daniel Figeys
     
 

ISBN-10: 0471457140

ISBN-13: 9780471457145

Pub. Date: 02/28/2005

Publisher: Wiley

This book covers both basic elements and the state-of-the-art in applications of proteomics. The first section gives an introduction to the field, from differential approaches to functional proteomics, including yeast two-hybrid, mass spectrometry, mapping of post-translational modifications, and NMR spectroscopy. The second section offers a complete picture of

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Overview

This book covers both basic elements and the state-of-the-art in applications of proteomics. The first section gives an introduction to the field, from differential approaches to functional proteomics, including yeast two-hybrid, mass spectrometry, mapping of post-translational modifications, and NMR spectroscopy. The second section offers a complete picture of industry studies in proteomics for human health and biotechnology applications. The final section addresses the future, looking at the most promising areas such as protein arrays and the integration of genomic and proteomic tools.

Product Details

ISBN-13:
9780471457145
Publisher:
Wiley
Publication date:
02/28/2005
Series:
Methods of Biochemical Analysis Series, #45
Pages:
324
Product dimensions:
6.12(w) x 9.47(h) x 0.59(d)

Table of Contents

Preface.

Contributors.

1. Proteomics: The Basic Overview (Daniel Figeys).

2. Mapping Protein-Protein Interactions (Daniel Figeys).

3. Protein Post-Translational Modifications: Phosphorylation Site Analysis Using Mass Spectrometry (Roland S. Annan and Francesca Zappacosta).

4. The Use of High Throughput Crystallography and In Silico Methods for Structure Based Drug Design (Leslie W. Tarr, Andy J. Jennings and Duncan E. McRee).

5. High Throughput Analysis of Protein Structure by H/D Exchange (H/D-Ex) Mass Spectrometry (Yoshitomo Hamuro, Patricia C. Weber and Patrick R. Griffin).

6. Proteomics Technologies for Identification and Validation of Protein Targets (John E. Hale, Weija Ou, Pavel Shiyanov, Michael D. Knierman and James R. Ludwig).

7. Proteomics Discovery of Biomarkers (Robert Massé and Bernard F. Gibbs).

8. Industrial-Scale Proteomics Analysis of Human Plasma (Keith Rose).

9. Chemical Genomics: Targets on Display (Steve Doberstein, Philip W. Hammond and René S. Hubert).

10. Bioinformatics for Proteomics (Christian Ahrens, Hans Jespersen and Soeren Schandorff).

11. Protein Arrays (David S. Wilson and Steffen Nock).

Index.

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