Infectious Diseases and Substance Abuse / Edition 1

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More About This Textbook


The influence of many drugs of abuse – licit and illicit – on immune function has been examined extensively in recent years. Many such substances, including marijuana, cocaine, morphine, and nicotine, have been shown to enhance the disease process by impairing immunologic function. Use of these drugs impairs immunologic functions by suppressing antibody function, decreasing cytokine production, enhancing production and release of IL1, and suppressing IL2 and interferon. Among the viruses known to be effected by these drugs are viruses such as herpes simplex virus and murine retrovirus and bacterial agents such as Staphylococcus, Listeria, Treponema, and Legionella.

This volume, part of the Infectious Agents and Pathogenesis series, examines a variety of drugs of abuse and how they affect the immune system.

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Product Details

  • ISBN-13: 9781441934666
  • Publisher: Springer US
  • Publication date: 12/6/2010
  • Series: Infectious Agents and Pathogenesis Series
  • Edition description: Softcover reprint of hardcover 1st ed. 2005
  • Edition number: 1
  • Pages: 212
  • Product dimensions: 0.53 (w) x 6.00 (h) x 9.00 (d)

Table of Contents

Effects of Cocaine and Morphine Withdrawal on the Immune Response.- Biological Links between Cannabinoids and HIV Infection.- Cannabinoids and Herpesviruses.- Cannabinoids and Susceptibility to Neurological Infection by Free-Living Amebae.- Legionella Infection and Cannabinoids.- Nicotine and Immunity.- Nicotine Receptors and Infections.- Immunomodulatory Effects of Cigarette Smoke/Nicotine.- Regulation of Chemokine and Chemokine Receptor Expression and Function by Opioids.- Morphine, Th1/Th2 Differentiation, and Susceptibility to Infection.- Immunofluorescence Detection of Anti-CD3-?-Induced Delta Opioid Receptors by Murine Splenic T Cells.- Modulation of Immune Function by Novel Opioid Receptor Ligands.- Effect of Alcohol on Microbial Infection.- Brucella Infection and Ethanol.- Alcohol, Infection, and the Lung.

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