BN.com Gift Guide

Inflammatory and Autoimmune Disorders of the Nervous System in Children / Edition 1

Hardcover (Print)
Used and New from Other Sellers
Used and New from Other Sellers
from $174.39
Usually ships in 1-2 business days
(Save 20%)
Other sellers (Hardcover)
  • All (3) from $174.39   
  • New (2) from $174.39   
  • Used (1) from $196.30   

Overview

Inflammatory disorders of the nervous system, although individually uncommon, collectively make up 10-20% of acute paediatric neurology presentations and many are potentially treatable. Research into them is lagging behind adult research, but better diagnosis and often simple treatments could lead to substantial clinical benefit and reduction in long-term disability.

This book provides a detailed and comprehensive summary of the childhood diseases that are, or are likely to be, caused by the immune system. The authors not only describe these disorders and their treatments comprehensively, helping pediatricians and pediatric neurologists to improve their understanding and recognition of the conditions, but also highlight recent and exciting developments that will be of considerable importance in the future. 

Read More Show Less

Editorial Reviews

Doody Reviews
Reviewer: Korwyn Williams, MD, PhD (Phoenix Children's Hospital)
Description: Written by international experts, this book surveys the breadth and depth of information in pediatric neuroimmunology.
Purpose: It includes the expected chapters on classification of central nervous system demyelination and autoantibodies involvement, but it also looks at the less intuitive associations of genetic mutations in inflammatory disease of the nervous system and inflammation in neurodegeneration syndromes and muscle disease. This is a timely collection given this rapidly evolving field. Overall, the authors succeed in illuminating these complicated topics.
Audience: The obvious audience is neurologists, both those in training and those practicing for years. Rheumatologists also might find the neurological perspectives illuminating. The book is certainly readable and written in such a way that readers can focus quite easily on immunology, clinical presentation, or management.
Features: Traditional topics such as central nervous demyelination (ADEM, MS, clinically isolated syndromes, optic neuritis) , acute cerebellar ataxia, myasthenia gravis, opsoclonus myoclonus syndrome, and systemic lupus erythematosus are well covered. More esoteric and newer entities such as NMDA encephalitis, Aicardi-Goutieres syndrome, hemophagocytic lymphohistiocytosis, macrophage activation syndrome, neurodevelopmental disorders associated with cerebral folate deficiency, and the immune system in genetic muscular dystrophies are also covered well in informative chapters. The authors are generous with illustrations and neuroimaging. The color plate section following the index is a particularly helpful addition. The well-edited chapters include a mix of basic immunology and clinical diseases. The book lends itself easily to a quick review or more leisurely, in-depth reading.
Assessment: Many of the topics in this book will be familiar to pediatric neurologists. The emphasis on the detailed immunological basis of the diseases is edifying. However, the role of the immune system in the pathophysiology of a disease like Charcot-Marie-Tooth syndrome is a surprise. Much of the information certainly can be found in scientific journals, but this is a worthy and helpful compendium.
Doody's Review Service
Reviewer: Korwyn Williams, MD, PhD (Phoenix Children's Hospital)
Description: Written by international experts, this book surveys the breadth and depth of information in pediatric neuroimmunology.
Purpose: It includes the expected chapters on classification of central nervous system demyelination and autoantibodies involvement, but it also looks at the less intuitive associations of genetic mutations in inflammatory disease of the nervous system and inflammation in neurodegeneration syndromes and muscle disease. This is a timely collection given this rapidly evolving field. Overall, the authors succeed in illuminating these complicated topics.
Audience: The obvious audience is neurologists, both those in training and those practicing for years. Rheumatologists also might find the neurological perspectives illuminating. The book is certainly readable and written in such a way that readers can focus quite easily on immunology, clinical presentation, or management.
Features: Traditional topics such as central nervous demyelination (ADEM, MS, clinically isolated syndromes, optic neuritis), acute cerebellar ataxia, myasthenia gravis, opsoclonus myoclonus syndrome, and systemic lupus erythematosus are well covered. More esoteric and newer entities such as NMDA encephalitis, Aicardi-Goutieres syndrome, hemophagocytic lymphohistiocytosis, macrophage activation syndrome, neurodevelopmental disorders associated with cerebral folate deficiency, and the immune system in genetic muscular dystrophies are also covered well in informative chapters. The authors are generous with illustrations and neuroimaging. The color plate section following the index is a particularly helpful addition. The well-edited chapters include a mix of basic immunology and clinical diseases. The book lends itself easily to a quick review or more leisurely, in-depth reading.
Assessment: Many of the topics in this book will be familiar to pediatric neurologists. The emphasis on the detailed immunological basis of the diseases is edifying. However, the role of the immune system in the pathophysiology of a disease like Charcot-Marie-Tooth syndrome is a surprise. Much of the information certainly can be found in scientific journals, but this is a worthy and helpful compendium.
From the Publisher
"This book is rich in information, tables, and illustrations, and I would strongly recommend it as a useful reference on a topic for which updated reviews are always needed." (The Lancet Neurology, October 2010)

“this is a well written book which I felt will be a valuable reference even for those who just have a superficial interest in autoimmune neurological disorders in children.” (European Journal of Paediatric Neurology, 2010)

“this book will be monumentally useful in resident education and very helpful for the practicing child neurologist. One good sign to this reviewer is that the more I use it, the better I like it.” (Journal of Child Neurology, 2011)

“Inflammatory and Autoimmune Disorders of the Nervous System in Children, by Russell C. Dale and Angela Vincent (Editors), is exactly the book every pediatric neurologist needs when he or she sees a child with neurological symptoms.” (Brain & Development , 2011)

“To my knowledge, the book is the first publication to provide comprehensive coverage of all of the important pediatric neuroimmunological disorders under one cover.” (Developmental Medicine and Child Neurology, 2011)

Read More Show Less

Product Details

  • ISBN-13: 9781898683667
  • Publisher: Wiley
  • Publication date: 12/9/2009
  • Series: Clinics in Developmental Medicine Series , #5
  • Edition description: New Edition
  • Edition number: 1
  • Pages: 448
  • Product dimensions: 7.00 (w) x 9.70 (h) x 1.62 (d)

Table of Contents

NEUROIMMUNOLOGY CONCEPTS

INTRODUCTION AND OVERVIEW Russell C. Dale (Australia) and Angela Vincent (UK)

INFLAMMATION AND AUTOIMMUNITY: A NERVOUS SYSTEM PERSPECTIVE Fabienne Brilot (Australia)

CENTRAL NERVOUS SYSTEM DISORDERS

DEMYELINATING SYNDROMES

OVERVIEW OF NEW INTERNATIONAL DEFINITIONS FOR CNS DEMYELINATION SYNDROMES IN CHILDREN Russell C. Dale (UK) and Silvia Tenembaum (Argentina)

ACUTE DISSEMINATED ENCEPHALOMYELITIS Silvia Tenembaum (Argentina) and Tanuja Chitnis (USA)

CHILDHOOD MULTIPLE SCLEROSIS Yann Mikaeloff, Russell C. Dale (Australia) and Marc Tardieu (France)

MULTIPLE SCLEROSIS: AN ADULTS PERSPECTIVE Gavin Giovannoni (UK)

TRANSVERSE MYELITIS Michael Levy and Douglas Kerr (USA)

OPTIC NEURITIS IN CHILDREN Brenda Banwell and Raymond Buncic (Canada)

REGIONAL NEUROINFLAMMATORY SYNDROMES

SYDENHAM’S CHOREA Francisco Cardoso (Brazil)

PAEDIATRIC AUTOIMMUNE NEUROPSYCHIATRIC DISORDERS ASSOCIATED WITH STREPTOCOCCAL INFECTION (PANDAS) Tanya Murphy and Ana Segarra (USA)

OPSOCLONUS MYCLONUS SYNDROME Michael Pranzatelli (USA)

OTHER IMMUNE-MEDIATED EXTRAPYRAMIDAL MOVEMENT DISORDERS Russell C. Dale (Australia)

POST-INFECTIOUS ATAXIA AND CEREBELLITIS Deepak Gill (Australia)

RASMUSSEN ENCEPHALITIS Christian Bien (Germany) and Jan Bauer (Austria)

SYSTEMIC AUTOIMMUNE DISORDERS AND VASCULITIS

NEUROPSYCHIATRIC MANIFESTATIONSD OF CHILDHOOD SYSTEMIC LUPUS ERYTHEMATOSUS AND ANTIPHOSPHOLIPID SYNDROME Liora Harel (Israel) and Emily von Scheven (USA)

CEREBRAL VASCULITIS Jorina Elbers and Susanne Benseler (Canada)

MACROPHAGE ACTIVATION SYNDROMES Marc Tardieu and Nizar Mahlaoui (France)

ORPHAN NEURO-INFLAMMATORY DISORDERS

AICARDI-GOUTIERES SYNDROME AND RELATED DISORDERS John B.P. Stephenson and Yanick J. Crow (UK)

NEONATAL ONSET MULTISYSTEMJ INFLAMMATORY DISORDER (NOMID)/CHRONIC INFANTILE NEUROLOGICAL CUTANEOUS SYNDROME (CINCA) Simon R. Ling (Singapore) and P. Ian Andrews (Australia)

FOLATE RECEPTOR AUTOIMMUNITY IN CEREBRAL FOLATE DEFICIENCY Vincent T. Ramaekers (Germany) and Edward V. Quadros (USA)

EMERGING CONCEPTS

INFLAMMATORY MECHANISMS IN NEURODEGENERATIVE DISORDERS Ming Lim, Mylvaganam Jeyakumar, and Francis Platt (UK)

GLUTAMATE RECEPTOR AUTOANTIBODIES IN NEUROLOGICAL SYNDROMES Mia Levite and Yonatan Ganor (Israel)

AUTOIMMUNE CHANNELOPATHIES: LESSONS FROM ADULT NEUROLOGY

PERIPHERAL NERVOUS SYSTEM DISORDERS

CHILDHOOD AUTOIMMUNE MYASTHENIA Jeremy Parr, Sandeep Jayawant, Camilla Buckley, and Angela Vincent (UK)

GUILLAIN-BARRE SYNDROME AND CHRONIC INFLAMMATORY DEMYELINATING POLYNEUROPATHY IN CHILDHOOD Monique M. Ryan, John D. Pollard, and Robert A. Ouvrier (Australia)

DERMATOMYOSITIS AND POLYMYOSITIS Elizabeth Stringer and Brian M. Feldman (Canada)

INFLAMMATORY MECHANISMS IN GENETIC NEUROMUSCULAR DISORDERS James G. Tidball and Michelle Wehling-Henriks (USA)

Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star

(0)

4 Star

(0)

3 Star

(0)

2 Star

(0)

1 Star

(0)

Your Rating:

Your Name: Create a Pen Name or

Barnes & Noble.com Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & Noble.com that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & Noble.com does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at BN.com or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation

Reminder:

  • - By submitting a review, you grant to Barnes & Noble.com and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Noble.com Terms of Use.
  • - Barnes & Noble.com reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & Noble.com also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on BN.com. It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

 
Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)