A cutting-edge review of the fundamental biological principles underlying the more common inflammatory disorders of the nervous system. The authors provide extensive updates on the latest findings concerning the mechanisms of inflammation and introduce such new concepts and methodologies as "endothelial and leukocyte microparticles" and "gene microarray technology" to help explain important links between the central nervous system (CNS) and general inflammatory processes. Among the diseases examined from an inflammatory perspective are multiple sclerosis, acute disseminated encephalomyelitis, optic neuritis, transverse myelitis, CNS vasculitis, neuropsychiatric systemic lupus erythematosis, Alzheimer's disease, and Parkinson's disease. The role of the immune system in neuroinflammation is also explored in such disorders as neurosarcoidois, HIV-Associated dementia, and HTLV-associated neurological disorders.
Our reader reviews allow you to share your comments on titles you liked,
or didn't, with others. By submitting an online review, you are representing to
Barnes & Noble.com that all information contained in your review is original
and accurate in all respects, and that the submission of such content by you
and the posting of such content by Barnes & Noble.com does not and will not
violate the rights of any third party. Please follow the rules below to help
ensure that your review can be posted.
Reviews by Our Customers Under the Age of 13
We highly value and respect everyone's opinion concerning the titles we offer.
However, we cannot allow persons under the age of 13 to have accounts at BN.com or
to post customer reviews. Please see our Terms of Use for more details.
What to exclude from your review:
Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the
information on the product page, please send us an email.
Reviews should not contain any of the following:
- HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
- Time-sensitive information such as tour dates, signings, lectures, etc.
- Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
- Comments focusing on the author or that may ruin the ending for others
- Phone numbers, addresses, URLs
- Pricing and availability information or alternative ordering information
- Advertisements or commercial solicitation
Reminder:
- By submitting a review, you grant to Barnes & Noble.com and its
sublicensees the royalty-free, perpetual, irrevocable right and license to use the
review in accordance with the Barnes & Noble.com Terms of Use.
- Barnes & Noble.com reserves the right not to post any review -- particularly
those that do not follow the terms and conditions of these Rules. Barnes & Noble.com
also reserves the right to remove any review at any time without notice.
- See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend
Create a Pen Name
Welcome, penname
You have successfully created your Pen Name. Start enjoying the benefits of the BN.com Community today.
If you find inappropriate content, please report it to Barnes & Noble
More About This Textbook
Overview
A cutting-edge review of the fundamental biological principles underlying the more common inflammatory disorders of the nervous system. The authors provide extensive updates on the latest findings concerning the mechanisms of inflammation and introduce such new concepts and methodologies as "endothelial and leukocyte microparticles" and "gene microarray technology" to help explain important links between the central nervous system (CNS) and general inflammatory processes. Among the diseases examined from an inflammatory perspective are multiple sclerosis, acute disseminated encephalomyelitis, optic neuritis, transverse myelitis, CNS vasculitis, neuropsychiatric systemic lupus erythematosis, Alzheimer's disease, and Parkinson's disease. The role of the immune system in neuroinflammation is also explored in such disorders as neurosarcoidois, HIV-Associated dementia, and HTLV-associated neurological disorders.
Product Details
Related Subjects
Table of Contents
Endothelial Cell-Leukocyte Interactions During CNS Inflammation
J. Steven Alexander and Alireza Minagar
Multiple Sclerosis: A Disease of Miscommunication Between the Immune and Central Nervous Systems?
Monica J. Carson, Crystal S. Anglen, and Corinne Ploix
Cytokines and Brain: Health and Disease
Tammy Kielian and Paul D. Drew
Chemokines and Central Nervous System Disorders
William J. Karpus
Circulating Cell-Derived Microparticles in Thrombotic and Inflammatory Disorders
Wenche Jy, Lawrence L. Horstman, Joaquin J. Jimenez, Alireza Minagar, and Yeon S. Ahn
Multiple Sclerosis: Clinical Features, Immunopathogenesis, and Clinical Management
William A. Sheremata
Neuroprotective Effects of Interferon-b in Multiple Sclerosis
Fabrizio Giuliani, Rana Zabad, and V. Wee Yong
Acute Disseminated Encephalomyelitis
Sean J. Pitk and Dean M. Wingerchuk
Ingested Type I Interferon in Experimental Autoimmune Encephalomyelitis
Staley A. Brod
Neuromyelitis Optica
Dean M. Wingerchuk
Transverse Myelitis: Clinical Manifestations, Pathogenesis, and Management
Chitra Krishnan, Adam I. Kaplin, Deepa M. Deshpande, Carlos A. Pardo, and Douglas A. Kerr
Optic Neuritis: Pathogenesis, Immunology, Diagnosis, and Clinical Management
Robert Zivadinov and Rohit Bakshi
Central Nervous System Vasculitis: Pathogenesis, Immunology, and Clinical Management
Shariq Mumtaz, Marjorie R. Fowler, Eduardo Gonzales-Toledo, and Roger E. Kelley
Neurosarcoidosis: Pathogenesis, Immunology, and Clinical Management
Dakshinamurty Gullapalli and Lawrence H. Phillips, II
Neuropsychiatric SLE: Pathogenesis, Immunology, and Clinical Management
Deborah Aleman-Hoey and Robin L. Brey
Gene Expression in HIV-Associated Dementia
Paul Shapshak, Alireza Minagar, Elda M. Duran, Fabiana Ziegler, Wade Davis, Raman Seth, and Toni Kazic
Human T-Lymphotropic Virus-Associated Neurological Disorders: Pathogenesis, Immunology, and Clinical Management
Michael D. Lairmore, Bindhu Michael, Lee Silverman, and Amrithraj Nair
West Nile Virus Infection of the Nervous System: Pathogenesis, Immunology, and Clinical Management
Douglas J. Lanska
Index