Insulin Resistance / Edition 1

Insulin Resistance / Edition 1

by David E. Moller
     
 

The past two decades have seen explosive gains in our understanding of the physiology and basic mechanisms of insulin action and the critical importance of insulin resistance in the pathogenesis of clinical disorders such as non-insulin dependent diabetes mellitus, essential hypertension and atherosclerotic cardiovascular disease.
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Overview

The past two decades have seen explosive gains in our understanding of the physiology and basic mechanisms of insulin action and the critical importance of insulin resistance in the pathogenesis of clinical disorders such as non-insulin dependent diabetes mellitus, essential hypertension and atherosclerotic cardiovascular disease.
Insulin Resistance offers the first comprehensive review of the field, with integrated chapters providing up to date coverage of the essential components of basic and clinical research that have contributed to current understanding of the topic. There are chapters on basic mechanisms of insulin action, in depth discussions of insulin resistance syndromes from epidemiological, clinical and biochemical viewpoints and a discussion of therapeutic approaches to insulin resistance.
Insulin Resistance will be an invaluable resource for clinicians and scientists with an interest in the mechanisms of insulin action, the clinical sequelae of hyperinsulinemia and future therapies of insulin resistance.

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Product Details

ISBN-13:
9780471939771
Publisher:
Wiley
Publication date:
01/28/1993
Edition description:
New Edition
Pages:
440
Product dimensions:
6.22(w) x 9.50(h) x 1.21(d)

Table of Contents

Mechanisms of Insulin Action (M. White & C. Kahn).

Syndromes of Severe Insulin Resistance: Clinical and Pathophysiological Features (D. Moller & S. O'Rahilly).

Mutations of the Insulin Receptor Gene (S. Taylor & D. Moller).

Autoimmune Mechanisms of Insulin Resistance and Hypoglycemia (P. Gorden, et al.).

Insulin Resistance and Its Role in the Pathogenesis of Impaired Glucose Tolerance and Non-Insulin-Dependent Diabetes Mellitus: Perspectives Gained from in Vivo Studies (A. Alzaid & R. Rizza).

Potential Cellular and Genetic Mechanisms for Insulin Resistance in the Common Disorders of Diabetes and Obesity (B. Seely & J. Olefsky).

Cellular Defects in Glucose Transport: Lessons from Animal Models and Implications for Human Insulin Resistance (P. Shepherd & B. Kahn).

Insulin Resistance and Ovarian Dysfunction (A. Dunaif).

Insulin Resistance in Hypertension (U. Smith).

Insulin Resistance, Hyperinsulinemia, Dyslipidemia and Atherosclerosis (R. Stout).

Therapeutic Approaches to Insulin Resistance (A. Moses & M. Abrahamson).

Index.

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