Insulin Resistance, Metabolic Diseases and Diabetic Complications: Proceedings of the 7th European Symposium on Metabolism, Padova, September 30-October 3, 1998 / Edition 1

Insulin Resistance, Metabolic Diseases and Diabetic Complications: Proceedings of the 7th European Symposium on Metabolism, Padova, September 30-October 3, 1998 / Edition 1

by Gaetano Crepaldi, S. Del Prato, A. Tiengo

ISBN-10: 0444500227

ISBN-13: 9780444500229

Pub. Date: 07/28/1999

Publisher: Elsevier Science

Product Details

Elsevier Science
Publication date:
ICS Series

Table of Contents

Insulin resistance and systemic atherosclerosis3
The Diabetes Intervention Study: impact of quality of risk factor control on coronary heart disease and mortality9
Glucose, insulin and atherosclerosis: Lessons from the Bruneck Study19
The plurimetabolic syndrome in the European population: the experience of the European Group on Insulin Resistance (EGIR)25
Results of 10-years genetic studies in French families with type 2 diabetes33
ACE genotype and diabetic nephropathy37
Apolipoprotein E gene polymorphism, vascular complications and nephropathy in NIDDM41
The atherogenic dyslipidemia of visceral obesity: need for preventive endocrinology47
Molecular and cellular markers of insulin resistance and diabetic complications
Nitric oxide and arginine55
Protein kinase C activation and the formation of diabetic vascular complications61
Molecular basis of insulin receptor activation, signal transduction and signalling specificity75
Regulation of metabolic gene expression by glucose83
Insulin resistance, endothelium and diabetic complications
Endothelium and diabetes. Evidences for a relationship between metabolic control and inappropriate nitric oxide production91
Effect of different lipoprotein fractions on nitric oxide and superoxide production in endothelial cells99
Renal complications
Diabetic nephropathy in IDDM and NIDDM: functional studies109
Diabetic nephropathy in Type 1 and Type 2 diabetes: structural studies117
Cellular markers for diabetic nephropathy129
Atherosclerotic complications
Dyslipidemia in diabetes: clinical importance of lipoprotein heterogeneity137
Heterogeneity of triglyceride-rich lipoproteins in the postprandial state143
The role of glycation in diabetic complications147
Oxidative stress and diabetic complications153
Triglycerides increase the biosynthesis of plasminogen activator inhibitor type I: focus on their mechanism of action159
Altered fatty acid partitioning by PPAR activators improves glucose homeostatis; a case for PPAR[alpha] and [gamma] coagonists167
Prevention of complications
The role of antihypertensive treatment in CHD prevention175
Antihypertensive therapy and cardiovascular complications181
Pharmacologic inhibition of the renin-angiotensin system and diabetic nephropathy187
Calcium channel blockers and incipient diabetic nephropathy193
Prevention of diabetic complications. Diet and cardiovascular disease: the epidemiological evidence201
Effects of dietary fat and carbohydrate on insulin resistance207
Secondary prevention of coronary heart disease in diabetes: a subgroup analysis of the Scandinavian Simvastatin Survival Study (4S)213
HMG-CoA reductase inhibitors in atherosclerosis219
Diabetes and atherosclerosis: a lipoprotein perspective225
Metformin and the treatment of the insulin resistance syndrome - The BIGPRO Studies237
Mechanism of action of thiazozidinediones in type 2 diabetes243
Leptin: a perspective for the weight control problem253
Carnitine system and insulin resistance259
Index of authors275

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