Description: This book reviews current data on interferons in the treatment of a variety of infectious, hematologic, and oncologic diseases.
Purpose: A summary of a symposium held in October 1995 is provided by this book, thereby compiling the current state of the art for the indications and use of recombinant interferons.
Audience: Physicians specializing in hematology and oncology will benefit most from this book, although a few chapters are relevant for physicians specializing in the areas of HIV, autoimmune diseases, and chronic hepatitis.
Features: Excellent, comprehensive tables summarize staging, treatment strategies, and the literature on the use of interferons in each disease state. Clear illustrations help to clarify treatment protocols and survival curves. References are up-to-date with regard to the 1995 conference.
Assessment: Each chapter reviews the basic biology of the disease, staging, and state-of-the-art therapy. A comprehensive summary of interferon trials completed and ongoing as of 1995 is provided. The text is fluent and well complemented by the tables. Unfortunately, some of the information is currently out of date; for example, interferons are now recommended for use in the adjuvant setting of high-risk malignant melanoma. Overall, this book is a well-written summary of these diseases and interferon therapy.