Interferons: Biological Activities and Clinical Efficacy

Interferons: Biological Activities and Clinical Efficacy

by Carlo Aul, Wolfgang Schneider
     
 

Interferons were among the first cytokines to be studied clinically in recombinant form in the 1980s, beginning a new era of pharmacotherapy in internal medicine. Interferons were soon employed in the treatment of tumors and it was shown that those hematopoietic neoplasias which had been difficult to treat with chemotherapy responded well to interferon treatment.

Overview

Interferons were among the first cytokines to be studied clinically in recombinant form in the 1980s, beginning a new era of pharmacotherapy in internal medicine. Interferons were soon employed in the treatment of tumors and it was shown that those hematopoietic neoplasias which had been difficult to treat with chemotherapy responded well to interferon treatment. In the present volume, renowned international authors update the importance of interferons in various fields of internal medicine, dermatology, and urology. The book also contains a general introduction into the classification, structure, and mode of action of interferons. Further chapters discuss the range of side effects of these substances and point out possible focuses of further clinical interferon research.

Editorial Reviews

Doody's Review Service
Reviewer: Lynn R. Kong, MD (Northwestern University Feinberg School of Medicine)
Description: This book reviews current data on interferons in the treatment of a variety of infectious, hematologic, and oncologic diseases.
Purpose: A summary of a symposium held in October 1995 is provided by this book, thereby compiling the current state of the art for the indications and use of recombinant interferons.
Audience: Physicians specializing in hematology and oncology will benefit most from this book, although a few chapters are relevant for physicians specializing in the areas of HIV, autoimmune diseases, and chronic hepatitis.
Features: Excellent, comprehensive tables summarize staging, treatment strategies, and the literature on the use of interferons in each disease state. Clear illustrations help to clarify treatment protocols and survival curves. References are up-to-date with regard to the 1995 conference.
Assessment: Each chapter reviews the basic biology of the disease, staging, and state-of-the-art therapy. A comprehensive summary of interferon trials completed and ongoing as of 1995 is provided. The text is fluent and well complemented by the tables. Unfortunately, some of the information is currently out of date; for example, interferons are now recommended for use in the adjuvant setting of high-risk malignant melanoma. Overall, this book is a well-written summary of these diseases and interferon therapy.
3 Stars from Doody
Lynn R. Kong
This book reviews current data on interferons in the treatment of a variety of infectious, hematologic, and oncologic diseases. A summary of a symposium held in October 1995 is provided by this book, thereby compiling the current state of the art for the indications and use of recombinant interferons. Physicians specializing in hematology and oncology will benefit most from this book, although a few chapters are relevant for physicians specializing in the areas of HIV, autoimmune diseases, and chronic hepatitis. Excellent, comprehensive tables summarize staging, treatment strategies, and the literature on the use of interferons in each disease state. Clear illustrations help to clarify treatment protocols and survival curves. References are up-to-date with regard to the 1995 conference. Each chapter reviews the basic biology of the disease, staging, and state-of-the-art therapy. A comprehensive summary of interferon trials completed and ongoing as of 1995 is provided. The text is fluent and well complemented by the tables. Unfortunately, some of the information is currently out of date; for example, interferons are now recommended for use in the adjuvant setting of high-risk malignant melanoma. Overall, this book is a well-written summary of these diseases and interferon therapy.

Product Details

ISBN-13:
9783540610519
Publisher:
Springer Berlin Heidelberg
Publication date:
12/28/1996
Pages:
281
Product dimensions:
6.10(w) x 9.25(h) x 0.03(d)

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