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Doody's Review ServiceReviewer: Gene A. Homandberg, PhD (Rush Medical College of Rush University)
Description: This book is intended to be an introduction to organic chemical descriptions of the major types of enzyme mechanisms. It begins with chapters on enzymes as proteins, enzyme catalysis, and study methods and continues with discussion of the six major types of enzyme mechanisms. The last chapter discusses nonenzymatic catalysis, as mediated by catalytic RNA and catalytic antibodies.
Purpose: This book is an attempt to present the major types of mechanisms together and to emphasize the chemical concepts. This is a worthwhile purpose for organic chemistry students, although there are many enzyme and general biochemistry books that do present mechanisms in sufficient detail and also discuss and more completely illustrate the role of protein structure. Because of this emphasis, this book would be useful to emphasize the features and relevance of biologic catalysts in an organic chemistry course.
Audience: The audience is intended to be primarily biochemists, and especially students; however, the book would also be suitable for organic chemists or instructors wishing to expand their knowledge or explain the relevance of protein catalysts.
Features: This book has an attractive, easy to read format and features numerous illustrations, problem sets and suggested additional reading throughout.
Assessment: This book would be a worthwhile addition to the library of biochemistry students or instructors, because it does comprehensively present the major types of mechanisms in an easy-to-read and understand style. Although there are many other excellent enzyme books with a different emphasis, this book would still be quite useful.