Introduction to Molecular Medicine / Edition 2

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1996 Trade paperback 2nd 1996. Corr. 2nd Printing ed. New. No dust jacket as issued. (Ac-A-5) Glued binding. 178 p. Audience: General/trade.

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Overview

This updated and revised third edition of INTRODUCTION TO MOLECULAR MEDICINE explains the fundamental principles vital to an understanding of the human genome, gene regulation and expression, and genetic engineering. Principles are then applied to the diagnosis and treatment of human disease in infectious diseases, inherited genetic diseases, the immune system and blood cells, cancer, and public health. Fully rewritten and with dozens of new illustrations, the Third Edition presents the basics of molecular biology and its impact on medicine in a concise, conversational format. Each chapter begins with an overview and ends with a summary. This edition also contains new discussions on the human genome project and genetic engineering with updated genetic maps.

Ross' Introduction to Molecular Medicine remains a must-have information source for all physicians, residents, and medical students, as the book's stellar reviews demonstrate:

"Well written and...presented in a style that is eminently readable...as an introduction to the applications of molecular biology and clinical medicine, Dr. Ross' book is recommended...of particular interest to pathology and clinical medicine residents." —ARCHIVES OF PATHOLOGY on the Second Edition.

"will appeal to students and clinicians who will appreciate an introduction to this complicated field which unlike others, is easy and good fun to read." — Annals of Oncology.

"...explains how an understanding of the human genome will affect the ability to diagnose and treat disease...numerous clinical examples are provided throughout to demonstrate the concepts & the pace of the revolution in molecular medicine.

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Editorial Reviews

From The Critics
Reviewer: Ian Glass, MD, FRCP, FRACP, FACMG (University of Washington School of Medicine)
Description: This is the third edition of a succinct 150-page book outlining the role of molecular biology in medicine. It is a timely publication, with the previous edition published eight years ago.
Purpose: The author aims to simply and directly describe the scientific advances of the molecular revolution, and summarize their various applications in medicine. Unlike other short, focused books, this book presents the "big picture," a lofty aim. Ambitiously, the author attempts to convey the awesome potential of the scientific techniques behind such advances in medical diagnosis, genetic counseling, and therapeutic approaches, all the while "keeping it simple," another worthy goal.
Audience: The book is divided into two parts; the first discusses the basics of molecular biology and genetics in less than 60 pages. In the second part, a molecular approach to disease is presented in general terms but uses specific and sometimes historic examples in infectious, genetic, immune, and neoplastic diseases. Finally, an ambitious chapter on molecular therapeutic approaches ensues. The appeal of this book lies in its accessibility. There are tables, line drawings/cartoons, and occasional photographic figures, which are relatively clear and simple in their presentation. Although used sparingly, they are sufficient to meet the aims of the book. Helpful and relevant readings are suggested at the end of each chapter.
Features: This book is intended primarily for physicians, especially those with only a passing acquaintance with the genetic revolution and who may not know where to begin to develop insights.
Assessment: This is a very impressive little book that very largely succeeds in its desire to summarize and to communicate rapid and sometimes bewildering scientific advances in medicine. Within the constraints of the size and length the author has self-imposed, the book manages in a low-key way to convey the excitement of the awesome potential of molecular genetics in diagnosis and therapeutic approaches. Moreover, the author’s intentions of "keeping it simple" gives it a freshness that few other books achieve. For those who seek that special combination of a small, simple, easy to read, "big picture" book, yet with comprehendible and specific illustrative examples, this is the book.
Booknews
Presents the discoveries, basic scientific concepts, and sense of excitement that surround the revolution in molecular medicine. The scientific basis of molecular medicine is presented simply and directly, but at a level of technical detail sufficient for the reader to appreciate the power of recombinant DNA technology. The volume is clinically oriented throughout. Annotation c. Book News, Inc., Portland, OR (booknews.com)

3 Stars from Doody
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Product Details

  • ISBN-13: 9780387944685
  • Publisher: Springer-Verlag New York, LLC
  • Publication date: 1/28/1996
  • Edition description: REV
  • Edition number: 2
  • Pages: 178
  • Product dimensions: 6.15 (w) x 9.26 (h) x 0.41 (d)

Table of Contents

Preface to the Third Edition
Preface to the Second Edition
Preface to the First Edition
Acknowledgments
I Basics of Molecular Biology
1 Human Genome 3
2 Gene Expression and Regulation 22
3 Genetic Engineering 35
II Molecular Approach to Disease
4 Infectious Diseases 59
5 Inherited Genetic Diseases 75
6 Immune System and Blood Cells 93
7 Cancer 108
8 Molecular Therapeutics 131
Conclusions 144
Glossary 147
Index 151
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