Introduction to Neuropsychopharmacology

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Introduction to Neuropsychopharmacology expands on the molecular and cellular foundations of the classic Biochemical Basis of Neuropharmacology, Eighth Edition (Cooper, Bloom, and Roth) by now including the behavioral methods used to study psychoactive drugs in experimental animals and in humans. Authored by four founders of modern neuroscience, this concise and comprehensive text covers the current series of medications used to treat diseases of the brain and nervous system--both psychiatric and neurologic--as well as legal and illegal recreational drugs and the neuroscientific information that explains how these medications act on the brain from the molecular to the clinical level. The text ranges from drugs that affect the mood and behavior to hypnotics, narcotics, anticonvulsants, and analgesics.
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Editorial Reviews

From The Critics
Reviewer: Michael Joel Schrift, D.O., M.A.(University of Illinois at Chicago College of Medicine)
Description: This is a marvelous new book (which is actually a version of the classic, The Biochemical Basis of Neuropharmacology, 8th edition, Cooper, Bloom and Roth (Oxford University Press, 2003)) covering "the principles by which the effects of drugs on behaviors, as well as on cells and circuits, are determined." Written and edited by giants in neuroscience, this book is a terrific addition to the medical literature.
Purpose: After the decision not to revise the eighth edition of Cooper, Bloom and Roth, the editors had a change of heart, but decided to relinquish "a lot of the academic minutiae" and produce this introductory textbook that focuses on "the study of drugs that affect the cells and circuits of the brain, and the brain's behavioral, emotional, and cognitive operations."
Audience: The targeted audience includes medical students as well as graduate students, house officers, and fellows.
Features: Topics covered include the cellular and molecular foundations, principles and methods, receptors, amino acid neurotransmitters, acetylcholine, catecholamines, serotonin, histamine, neuropeptides, purinergic pharmacology, and other interneuronal signals. In addition, the principles of CNS drug development for neurological and psychiatric disorders are covered. Clinically useful chapters cover such topics as antidepressants, antipsychotics, cognitive disorders, movement disorders, pain, epilepsy, recreational psychoactive drugs, psychostimulants, opiates, psychedelics, cannabis, alcohol, and nicotine.
Assessment: "This informative and readable new introductory textbook of neuropsychopharmacology should be required reading for any medical student, graduate student, or physician interested understanding neuroscience. It is an outstanding learning tool. "
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Product Details

  • ISBN-13: 9780195380538
  • Publisher: Oxford University Press, USA
  • Publication date: 12/12/2008
  • Edition description: New Edition
  • Pages: 576
  • Sales rank: 428,056
  • Product dimensions: 6.10 (w) x 9.20 (h) x 1.00 (d)

Table of Contents

1 Introduction to Neuropsychopharmacology 3

2 Cellular and Molecular Foundations of Neuropsychopharmacology 6

3 Principles and Methods of Behavioral Pharmacology 29

4 Receptors 58

5 Amino Acid Neurotransmitters 85

6 Acetylcholine 128

7 Catecholamines 150

8 Serotonin 214

9 Histamine 238

10 Neuropeptides 254

11 Purinergic Pharmacology 269

12 Other Interneruronal Signals 277

13 Treatments for Neurological or Psychiatric Disorders: Principles of Central Nervous System Drug Development 293

14 Antidepressants and Anxiolytics 306

15 Antipsychotics 336

16 Cognitive Disorders 355

17 Movement Disorders 389

18 Pain 405

19 Epilepsy 416

20 Recreational Psychoactive Drugs 424

21 Psychostimulants 447

22 Heroin and Other Opiates 473

23 Psychedelics 482

24 Cannabis 490

25 Alcohol 503

26 Nicotine 519

Index 533

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