Ion Channels: Molecules in Action / Edition 1

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Overview

Ion channels are crucial components of living cells. Situated in the cell membrane, they allow ions to pass from one side of the membrane to the other. This book provides an overview of ion channel study, including up-to-date coverage of the permeability and selectivity of channels, their gating and modulation, their response to drugs and toxins, and the human diseases that result from channel malfunction. Students of molecular biology, biochemistry, physiology, and neurobiology will benefit from this modern, concise text.

The book contains black-and-white illustrations.

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Editorial Reviews

From The Critics
Reviewer: Simon T. Alford, PhD (Northwestern University Feinberg School of Medicine)
Description: This is a comprehensive treatise on the properties of ion channels in the external and internal membrane of cells. The book covers the basic properties of ion channels, including gating, kinetics of activation and inactivation, ion selectivity, and the molecular biology of ion channels.
Purpose: It is intended to provide an introduction to the study and the properties of ion channels. I consider the objectives to be very worthwhile; ion channels are basic to the very notion of life. The book meets these aims well, although the book goes somewhat beyond the level of an introductory text.
Audience: Although the text is aimed at high-level undergraduate and graduate students in the biomedical sciences, I would consider it particularly useful to graduate students and for other researchers needing to gain insights in this area if it is outside their immediate research interests.
Features: The book is well illustrated, and the references are pertinent if a little dated simply because this is a field that moves very quickly.
Assessment: I found this book to be an exceptionally useful source. It appears accurate, although it will suffer from rapid dating in this field of study. The text will be particularly useful for graduate students starting work in areas of research involving ion channels and for more senior academics looking for information outside of their field. I would recommend this for library purchase and would buy it myself.
Simon T. Alford
This is a comprehensive treatise on the properties of ion channels in the external and internal membrane of cells. The book covers the basic properties of ion channels, including gating, kinetics of activation and inactivation, ion selectivity, and the molecular biology of ion channels. It is intended to provide an introduction to the study and the properties of ion channels. I consider the objectives to be very worthwhile; ion channels are basic to the very notion of life. The book meets these aims well, although the book goes somewhat beyond the level of an introductory text. Although the text is aimed at high-level undergraduate and graduate students in the biomedical sciences, I would consider it particularly useful to graduate students and for other researchers needing to gain insights in this area if it is outside their immediate research interests. The book is well illustrated, and the references are pertinent if a little dated simply because this is a field that moves very quickly. I found this book to be an exceptionally useful source. It appears accurate, although it will suffer from rapid dating in this field of study. The text will be particularly useful for graduate students starting work in areas of research involving ion channels and for more senior academics looking for information outside of their field. I would recommend this for library purchase and would buy it myself.

3 Stars from Doody
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Product Details

  • ISBN-13: 9780521498821
  • Publisher: Cambridge University Press
  • Publication date: 8/28/2003
  • Edition description: New Edition
  • Edition number: 1
  • Pages: 320
  • Product dimensions: 7.44 (w) x 9.69 (h) x 0.67 (d)

Table of Contents

Preface; 1. Introduction; 2. Ions on the move; 3. Investigating channel activity; 4. Molecular structures; 5. Permeability and selectivity; 6. Gating and modulation; 7. Drugs and toxins; 8. Dysfunctional channels in human disease; 9. Not the last word; References; Index.

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