Ionic Channels and Effect of Taurine on the Heart / Edition 1

Ionic Channels and Effect of Taurine on the Heart / Edition 1

by Denis Noble
     
 

ISBN-10: 0792321995

ISBN-13: 9780792321996

Pub. Date: 09/11/2008

Publisher: Springer US

This book is based on papers presented at a Symposium held in Seoul, Korea in 1992. The idea for the symposium developed naturally from work by the editors and their colleagues on the possible role of certain amino acids, like taurine, that are strongly concentrated by the cells of the heart, and the relationship between such acids and membrane ionic currents.

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Overview

This book is based on papers presented at a Symposium held in Seoul, Korea in 1992. The idea for the symposium developed naturally from work by the editors and their colleagues on the possible role of certain amino acids, like taurine, that are strongly concentrated by the cells of the heart, and the relationship between such acids and membrane ionic currents.
The first obvious question was whether it is possible to identify the transport mechanisms involved for taurine and whether they are electrogenic. The second question is what function could be served by such processes: does taurine play an essential role in cardiac tissue and is this important in protecting the heart from disease? A number of the world's leading cardiac electrophysiologists and taurine specialists attended the symposium to discuss these questions.
The papers in this volume range all the way from fundamental research on ionic current mechanisms in the heart to the use of taurine in clinical practice. The book will certainly stimulate further research in this field.

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Product Details

ISBN-13:
9780792321996
Publisher:
Springer US
Publication date:
09/11/2008
Series:
Developments in Cardiovascular Medicine Series, #141
Edition description:
1993
Pages:
171
Product dimensions:
6.10(w) x 9.25(h) x 0.02(d)

Table of Contents

Contributors
Preface
1Introduction to the Study and Role of Background Current Mechanisms in the Heart1
2Catecholamine-Induced Chloride Current in Cardiac Myocytes19
3Modulation of the Atrial Muscarinic-Gated K Current by Phosphorylation57
4Intracellular Taurine, Intracellular Sodium and Defense Against Cellular Damage73
5Taurine Effects on Ion Channels of Cardiac Muscle93
6Effect of Taurine on the Activation of Background Current in Cardiac Myocytes of the Rabbit119
7Protective Effect of Taurine on the Failing Heart and Its Clinical Application139
8Concluding Remarks163
Index169

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