Italian Consensus for the Classification and Reporting of Thyroid Cytology

by Fulvio Basolo (Editor), Anna Crescenzi (Editor), Guido Fadda (Editor), Andrea Frasoldati (Editor), Francesco Nardi (Editor)

Overview

This updated edition of the Italian Consensus for Classification and Reporting of Thyroid Cytology (ICCRTC) integrates the evolution in the field of thyroid pathology and the new approaches in the management of thyroid diseases. The five categories defined in the 2014 Consensus edition, with the separation of indeterminate nodules into TIR3A and TIR3B subcategories, are retained due to their effective stratification of malignancy risk.

The 2024 Consensus update has been developed by pathologists and endocrinologists with recognised expertise in thyroid disease and has been endorsed by their respective scientific societies: Società Italiana di Anatomia Patologica e Citologia Diagnostica (SIAPeC-IAP), Associazione Italiana Tiroide (AIT), Associazione Medici Endocrinologi (AME), Società Italiana di Endocrinologia (SIE).

This book includes chapters on sampling techniques, ultrasound imaging, molecular testing, oncocytes and translatability between major reporting systems. Enhanced with videos of WSI from cytology slides explaining morphological criteria for category selection, and with interactive self-assessment flashcards, this book will help pathologists to report thyroid cytology diagnoses, and endocrinologists to correctly interpret cytology reports for patient management.

Product Details

ISBN-13:	9783031940736
Publisher:	Springer Nature Switzerland
Publication date:	09/27/2025
Pages:	155
Product dimensions:	7.01(w) x 10.00(h) x (d)

About the Author

BASOLO Fulvio is professor of Anatomic Pathology at the University of Pisa. His research activity focuses mainly on thyroid cytopathology and molecular pathology of thyroid nodules and tumors. He leaded several national and international research projects, and contributed to writing of the Italian guidelines for oncological treatment of thyroid cancer. He has authored more than 350 papers on international journals.

CRESCENZI Anna is a Medical doctor specialized in Anatomic Pathology and is Associate Professor of pathology at Department of Radiological Sciences, Oncology and Anatomical Pathology, Sapienza University of Rome. Member of national and international board for guidelines for thyroid pathology diagnosis and management. Received grants as PI from Italian Ministry of Health. Author of 155 papers on international peer reviewed journals.

FADDA Guido is professor of Pathology at Università degli Studi di Messina, Facoltà di Medicina e Chirurgia. He has authored 206 papers on international journals.

FRASOLDATI Andrea is Head of Endocrinology Unit at Azienda Ospedaliera Santa Maria Nuova di Reggio Emilia. He has authored 62 papers on international journals.

NARDI Francesco former Professor of Pathology, Faculty of Medicine and Surgery, University Sapienza, Rome. He has authored 118 papers on international journals.

PALOMBINI Lucio is professor emeritus Faculty of Medicine and Surgery, University Federico II, Naples. He is Director of “Centro Barberio” Pathology Laboratory. He has authored 127 papers on international journals.

PAPINI Enrico is Scientific Director of the Regina Apostolorum Hospital – Lifenet Health in Albano, Rome, and Consultant Endocrinologist in the Institution. The scientific contributions, covering more than 200 original manuscripts in English language, textbook chapters and Italian and International Thyroid and Endocrinology Guidelines in the following areas: Ultrasound (US) assessment of thyroid gland: From the early 1990s, EP proposed this technique as a major diagnostic tool for thyroid nodules and defined the main US risk features for thyroid malignancy. Minimally invasive treatments for thyroid lesions: EP pioneered thyroid interventional procedures, with ethanol and thermal ablation, for benign thyroid nodules and nonsurgical management of thyroid cancer recurrences and microcarcinomas.

PONTECORVI Alfredo is Professor of Endocrinology, Catholic University of Rome. He is Head of Endocrinology and Internal Medicine Unit at Fondazione Policlinico Universitario Agostino Gemelli IRCCS. He has authored 397 papers on international journals.

Table of Contents

1. Introduction to the 3rd Edition.- 2. Recommendations for good clinical practice.- 3. Sampling procedure and preparatory technique.- 4. TIR1 Nondiagnostic.- 5. TIR2 Benign/Non - Malignant.- 6. TIR3A indeterminate lesion, probably benign.- 7. TIR3B Indeterminate lesion with intermediate risk of malignancy.- 8. TIR 4 - Suspicious for malignancy.- 9. TIR 5 - Malignant.- 10. Additional techniques.- 11. Oncocytic cells - nature and significance.- 12. Thyroid ultrasound examination and reporting.- 13. Translatability of the Cytological Categories from the Italian Consensus into the Bethesda and British Classifications.- 14. Key features and clinical remarks.