Jenner on Trial: An Ethical Examination of Vaccine Research in the Age of Smallpox and the Age of AIDS

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Overview

This book examines how an Ethics Review Committee using today's ethical standards as articulated in The Nuremburg Code, and the WHO/CIOMS International Ethical Guidelines for Biomedical Research Involving Human Subjects, might assess the scientific and ethical design of Edward Jenner's first experimental vaccine experiment. It explores the potential risks and benefits to young James, the adequacy of the preliminary evidence that Jenner used to justify performing his experiment, and how he might have complied with requirements for informed consent. In addition to its historical interest for 18th century England and for the origins of today's biomedical research ethics standards, the book is significant as a case study in the ethics of basic vaccine research. It thus raises relevant questions about today's vaccine research, particularly relating to HIV.
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Product Details

  • ISBN-13: 9780761807193
  • Publisher: University Press of America
  • Publication date: 4/30/1997
  • Pages: 116
  • Product dimensions: 5.30 (w) x 8.40 (h) x 0.40 (d)

Meet the Author

Thomas A. Kerns is Professor of Philosophy in the Social Science Division at North Seattle Community College in Seattle, Washington.
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Table of Contents

Preface
Acknowledgments
Introduction
l Smallpox and AIDS 5
2 A bit of history 9
3 Edward Jenner comes alive 23
4 ERC application materials 27
5 The ethical review 47
6 Dr Jenner and the Nazi doctors 63
7 Comparison of Dr Jenner's experiments with today's HIV vaccine experiments 69
8 One final word 81
Appendices 83
App. I The Nuremberg Code 85
App. II WHO/CIOMS International Ethical Guidelines 89
Selected Bibliography 95
Endnotes 99
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