Karch's Pathology of Drug Abuse, Third Edition / Edition 3

Karch's Pathology of Drug Abuse, Third Edition / Edition 3

by Steven B. Karch, Olaf Drummer, Steven B. Karch, MD, FFFLM
     
 

ISBN-10: 0849303435

ISBN-13: 9780849303432

Pub. Date: 12/26/2001

Publisher: Taylor & Francis

AUTHORITATIVE INFORMATION FROM THE SOURCE YOU TRUST

The third edition of Karch's Pathology of Drug Abuse continues to provide a comprehensive yet accessible guide to the pathology, toxicology, and pharmacology of commonly abused drugs. As in previous editions, the focus remains on the investigation of drug-related deaths and on practical approaches to the

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Overview

AUTHORITATIVE INFORMATION FROM THE SOURCE YOU TRUST

The third edition of Karch's Pathology of Drug Abuse continues to provide a comprehensive yet accessible guide to the pathology, toxicology, and pharmacology of commonly abused drugs. As in previous editions, the focus remains on the investigation of drug-related deaths and on practical approaches to the detection of drug abuse. It covers in detail the clinical consequences of drug usage and provides the latest information on clinical aspects of drug abuse. This well-written, extensively referenced resource supplies a mixture of clinical information and pathology findings.

SEE WHAT'S NEW IN THE THIRD EDITION:

  • New information on methamphetamine abuse
  • New chapter on GHB, ketamine, and select herbal hallucinogens
  • New micrographs showing pathology of drug related deaths
  • Over 1000 new references
  • The mechanism of sudden death in cocaine users and overdose in heroin abusers
  • Toxicology and pathology of ephedrine
  • Neurochemistry of excited delirium
  • Psychotic behavior in stimulant abusers

    About the author: Steven B. Karch has appeared as an expert witness in international cases, including advice to counsel in the Harold Shipman murder trial. He is an assistant medical examiner in San Francisco, where he consults on cases of drug-related deaths. He received his bachelors degree from Brown University, did graduate work in cell biology and biophysics at Stanford, and received his M.D. from Tulane University Medical School.

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    Product Details

    ISBN-13:
    9780849303432
    Publisher:
    Taylor & Francis
    Publication date:
    12/26/2001
    Edition description:
    REV
    Pages:
    568
    Product dimensions:
    7.00(w) x 10.10(h) x 1.50(d)

    Table of Contents

    COCAINE
    Incidence
    Epidemiology
    History
    Cultivation and Manufacture
    Drug Constants
    Routes of Ingestion
    Metabolism of Cocaine and Its Metabolites
    Problems of Test Interpretation
    Cocaine Tissue Disposition
    Cocaine's Effects on Catecholamine and the Heart
    External Markers of Cocaine Abuse
    Toxicity by Organ System
    When is Cocaine the Cause of Death?

    OTHER NATURALLY OCCURRING STIMULANTS
    Absinthe
    Caffeine
    Ephedrine
    Khat

    SYNTHETIC STIMULANTS
    Amphetamine and Methamphetamine
    Methylphenidate (Ritalin™)
    Phenylpropanolamine
    Fenfluramine

    HALLUCINOGENS
    Phenylethylamine Derivatives
    Substituted Amphetamines (Phenylisopropylamines)
    Phenylalkylamines

    NARCOTICS
    Incidence
    Epidemiology
    Classification of Narcotic Agents
    History of Opiate Abuse
    Cultivation and Manufacture
    Opiate Classification
    Interpretation of Blood and Tissue Concentrations
    Medical Consequences of Opiate Abuse
    Pulmonary Disorders

    DISASSOCIATIVE ANESTHETICS
    Phencyclidine
    Ketamine
    Gamma-hydroxybutyrate (GHB)

    ANABOLIC STEROIDS
    Incidence
    Epidemiology
    History
    Steroid Abuse
    Pharmacology
    Steroid-related Disorders
    Detecting Steroid Abuse

    SOLVENTS
    Incidence
    Epidemiology
    General considerations
    Absorption and tissue disposition
    Clinical syndromes
    Appendix 1: Conversion Formulas
    Appendix 2: Blood Alcohol Concentrations
    Appendix 3: Volume of Distribution Calculations
    Appendix 4: Normal Heart Weights

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