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Khan's Lectures: Handbook of the Physics of Radiation Therapy

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Overview

This handbook provides a digest of the material contained in Dr. Khan's The Physics of Radiation Therapy, Fourth Edition.

The material is based on the pearls of wisdom that Dr. Khan presents in his renowned lectures. This book is written for the radiotherapy team: radiation oncologists, medical physicists, dosimetrists, and therapists. Since the information is presented in a concise manner, it is ideal for board exams and recertification.

Inside you'll find…

Highly formatted lectures discussion of key points

Multiple choice questions following each chapter

An answer key at the end of the book

Access to a website with an interactive question bank

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Product Details

  • ISBN-13: 9781605476810
  • Publisher: Lippincott Williams & Wilkins
  • Publication date: 6/27/2011
  • Pages: 400
  • Product dimensions: 7.00 (w) x 10.00 (h) x 0.60 (d)

Table of Contents

Preface vii

CHAPTER 1:

Structure of MatterLecture 1A

Lecture 1B

The Atom . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3Forces of Nature and Fundamental Particles . . . . . . . 7Review Questions

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11CHAPTER 2:

Nuclear TransformationsLecture 2A

Lecture 2B

Radioactivity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15Nuclear Reactions . . . . . . . . . . . . . . . . . . . . . . . . . . 23Review Questions

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27CHAPTER 3:

Production of X-RaysLecture 3A

Lecture 3B

X-Ray Tubes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 31Physics of X-Ray Production . . . . . . . . . . . . . . . . . . 37Review Questions

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41CHAPTER 4:

Clinical Radiation GeneratorsLecture 4A

Lecture 4B

X-Ray and Electron Beams . . . . . . . . . . . . . . . . . . . . 45Heavy Particle Accelerators . . . . . . . . . . . . . . . . . . . 55Review Questions

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 60CHAPTER 5:

Interactions of Ionizing RadiationLecture 5A

Lecture 5B

Photon Interactions . . . . . . . . . . . . . . . . . . . . . . . . . 65Particle Interactions . . . . . . . . . . . . . . . . . . . . . . . . . 72Review Questions

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 76CHAPTER 6:

Measurement of Ionizing RadiationLecture 6A

Lecture 6B

Measurement of Exposure . . . . . . . . . . . . . . . . . . . . 81Chambers and Electrometers . . . . . . . . . . . . . . . . . . 87Review Questions

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 92CHAPTER 7:

Quality of X-Ray BeamsLecture 7

Beam Quality . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Specification and Measurement of X-Ray97Review Questions

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 102CHAPTER 8:

Measurement of Absorbed DoseLecture 8A

Lecture 8B

Dosimetry Concepts . . . . . . . . . . . . . . . . . . . . . . . 107Dosimeters . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 113Review Questions

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 119CHAPTER 9:

Dose Distribution and Scatter AnalysisLecture 9

Depth Dose and Tissue-Air Ratios . . . . . . . . . . . . . . 125Review Questions

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 133CHAPTER 10:

A System of Dosimetric CalculationsLecture 10

Formalism for Monitor Units Calculation . . . . . . . 139Review Questions

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 148CHAPTER 11:

Distributions

Treatment Planning I: IsodoseLecture 11

Isodose Distribution and Plan Evaluation . . . . . . . 153Review Questions

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 170CHAPTER 12:

Corrections, and Setup

Treatment Planning II: Patient Data,Lecture 12A

Treatment Verification . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Lecture 12B:

Inhomogeneities . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Patient Data Acquisition, Simulation, and175Corrections for Irregular Surface and Tissue183Review Questions

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 190Contents

xiCHAPTER 13:

Skin Dose, and Field Separation

Treatment Planning III: Field Shaping,Lecture 13

Field Separation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Field Shaping, Surface Dose, and195Review Questions

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 204CHAPTER 14:

Electron Beam TherapyLecture 14A

Lecture 14B

Electron Beam Interactions and Dosimetry . . . . . 209Electron Beam Treatment Planning . . . . . . . . . . . 220Review Questions

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 234CHAPTER 15:

BrachytherapyLecture 15

Implantation and Dose Specification . . . . . . . . . . . . . . . . . . .

Low-Dose-Rate Brachytherapy: Rules of239Review Questions

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 249CHAPTER 16:

Radiation ProtectionLecture 16

Radiation Protection and Shielding Design . . . . . . 253Review Questions

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 261CHAPTER 17:

Quality AssuranceLecture 17

Quality Assurance and Maintenance . . . . . . . . . . . . 267Review Questions

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 273CHAPTER 18:

Total Body IrradiationLecture 18

and Dosimetry . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Total Body Irradiation: Techniques277Review Questions

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 282CHAPTER 19:

Radiation Therapy

Three-Dimensional ConformalLecture 19

Treatment Planning . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

3D Conformal Radiotherapy: Dosimetry and287Review Questions

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 295xii

ContentsCHAPTER 20:

Intensity-Modulated Radiation TherapyLecture 20

and Delivery . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

IMRT: Commissioning, Treatment Planning,299Review Questions

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 308CHAPTER 21:

Stereotactic Radiation TherapyLecture 21

Stereotactic Radiotherapy and Radiosurgery . . . . . . 313Review Questions

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 320CHAPTER 22:

High-Dose-Rate BrachytherapyLecture 22

Treatment Planning . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

High-Dose-Rate Brachytherapy: Dosimetry and325Review Questions

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 330CHAPTER 23:

Prostate ImplantsLecture 23

Treatment Planning . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Prostate Implants: Technique, Dosimetry, and335Review Questions

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 343CHAPTER 24:

Intravascular BrachytherapyLecture 24

and Dosimetry . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Intravascular Brachytherapy: Techniques347Review Questions

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 352CHAPTER 25:

Image-Guided Radiation TherapyLecture 25

Tracking, and Imaging Dose . . . . . . . . . . . . . . . . . . . . . . . . .

IGRT: On-Board Imagers, Online Tumor355Review Questions

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 364CHAPTER 26:

Proton Beam TherapyLecture 26

Treatment Planning . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Proton Beam Therapy: Dosimetry and367Review Questions

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 377Answers

Index 383

379

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