Laminins / Edition 1

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More About This Textbook

Overview

Many of the most exciting new discoveries concerning tissue-specific laminins and the vital role of different laminins are addressed. By covering topics such as gene coding for laminins, genetic diseases affecting laminins, evolutionary aspects, embryonic development, apoptosis, neurite outgrowth and cancer, this book provides a basis for understanding the role of laminins in development and disease.
The Laminins provides detailed knowledge about the molecular features of the laminins and describes the structure-function relationships and interactions that define their biologically active domains.
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Product Details

  • ISBN-13: 9783718658077
  • Publisher: CRC Press
  • Publication date: 9/1/1996
  • Series: Cell Adhesion and Communication Series
  • Edition description: New Edition
  • Edition number: 1
  • Pages: 336
  • Product dimensions: 7.05 (w) x 10.00 (h) x 0.84 (d)

Table of Contents

Preface to the Series
Preface
Contributors
1 Biosynthesis, tissue distribution and isolation of laminins 1
2 Structure of laminins and their chain assembly 27
3 Laminin genes: structure, regulation and mutations in disease 51
4 Laminins in epidermal structures 65
5 Binding of laminins to extracellular matrix components 97
6 Integrin-mediated cellular interactions with laminins 127
7 Non-integrin laminin receptors 159
8 Laminin isoforms in development 185
9 Basement membrane as a differentiation and survival factor 217
10 Drosophila laminin 235
11 Laminins during neurite growth and nerve regeneration 251
12 Interaction of tumor cells with basement membranes and laminin-1 277
13 Dystroglycan: a novel laminin receptor and its involvement in the pathogenesis of muscular dystrophy 291
Index 317
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